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| Author | : Andrew Witt |
| Publisher | : MIT Press |
| Total Pages | : 433 |
| Release | : 2022-01-11 |
| Genre | : Architecture |
| ISBN | : 0262543001 |
Download Formulations Book in PDF, ePub and Kindle
An investigation of mathematics as it was drawn, encoded, imagined, and interpreted by architects on the eve of digitization in the mid-twentieth century. In Formulations, Andrew Witt examines the visual, methodological, and cultural intersections between architecture and mathematics. The linkages Witt explores involve not the mystic transcendence of numbers invoked throughout architectural history, but rather architecture’s encounters with a range of calculational systems—techniques that architects inventively retooled for design. Witt offers a catalog of mid-twentieth-century practices of mathematical drawing and calculation in design that preceded and anticipated digitization as well as an account of the formal compendia that became a cultural currency shared between modern mathematicians and modern architects. Witt presents a series of extensively illustrated “biographies of method”—episodes that chart the myriad ways in which mathematics, particularly the mathematical notion of modeling and drawing, was spliced into the creative practice of design. These include early drawing machines that mechanized curvature; the incorporation of geometric maquettes—“theorems made flesh”—into the toolbox of design; the virtualization of buildings and landscapes through surveyed triangulation and photogrammetry; formal and functional topology; stereoscopic drawing; the economic implications of cubic matrices; and a strange synthesis of the technological, mineral, and biological: crystallographic design. Trained in both architecture and mathematics, Witt uses mathematics as a lens through which to understand the relationship between architecture and a much broader set of sciences and visual techniques. Through an intercultural exchange with other disciplines, he argues, architecture adapted not only the shapes and surfaces of mathematics but also its values and epistemic ideals.
| Author | : Barbara Lichner Ingram |
| Publisher | : John Wiley & Sons |
| Total Pages | : 729 |
| Release | : 2011-03-10 |
| Genre | : Psychology |
| ISBN | : 1118046293 |
Download Clinical Case Formulations Book in PDF, ePub and Kindle
A step-by-step model for individualized case conceptualization This innovative new guide addresses the essential question facing every therapist with a new client: How do I create a treatment plan that is the best match for my client? This unique resource provides a systematic method to integrate ideas, skills, and techniques from different theoretical approaches, empirical research, and clinical experience to create a case formulation that is tailor-made for the client. Clinical Case Formulations is divided into three parts: * Getting Started--provides an overview that sets forth a framework for case formulation and data gathering. * 28 Core Clinical Hypotheses--offers a meta-framework embracing all theories, orientations, and mental health intervention models and presents clinical hypotheses within seven categories: Biological Hypotheses; Crisis, Stressful Situations, and Transitions; Behavioral and Learning Models; Cognitive Models; Existential and Spiritual Models; Psychodynamic Models; and Social, Cultural, and Environmental Factors. These hypotheses are combined and integrated to develop a coherent conceptualization of the client's problems. * Steps to a Complete Case Formulation--provides a structured framework known as the Problem-Oriented Method (POM). Using the POM and integrating multiple hypotheses, the therapist learns how to think intelligently, critically, and creatively in order to develop a tailor-made treatment plan. A list of thirty-three standards for evaluating the application of this method is provided. With this practical guide you will learn to conceptualize your clients' needs in ways that lead to effective treatment plans while finding the tools for troubleshooting when interventions fail to produce expected benefits.
| Author | : John F. Carpenter |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 218 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461505577 |
Download Rational Design of Stable Protein Formulations Book in PDF, ePub and Kindle
Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.
| Author | : Geoffrey D Tovey |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 432 |
| Release | : 2018-06-25 |
| Genre | : Science |
| ISBN | : 1849739412 |
Download Pharmaceutical Formulation Book in PDF, ePub and Kindle
Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.
| Author | : Ronald Snee |
| Publisher | : SAS Institute |
| Total Pages | : 294 |
| Release | : 2016-09-27 |
| Genre | : Computers |
| ISBN | : 1629605301 |
Download Strategies for Formulations Development Book in PDF, ePub and Kindle
Strategies for Formulations Development: A Step-by-Step Guide Using JMP is based on the authors' significant practical experience partnering with scientists to develop strategies to accelerate the formulation (mixtures) development process. The authors not only explain the most important methods used to design and analyze formulation experiments, but they also present overall strategies to enhance both the efficiency and effectiveness of the development process. With this book you will be able to: Approach the development process from a strategic viewpoint with the overall end result in mind. Design screening experiments to identify components that are most important to the performance of the formulation. Design optimization experiments to identify the maximum response in the design space. Analyze both screening and optimization experiments using graphical and numerical methods. Optimize multiple criteria, such as the quality, cost, and performance of product formulations. Design and analyze formulation studies that involve both formulation components and process variables using methods that reduce the required experimentation by up to 50%. Linking dynamic graphics with powerful statistics, JMP helps construct a visually compelling narrative to interactively share findings that are coherent and actionable by colleagues and decision makers. Using this book, you can take advantage of computer generated experiment designs when classical designs do not suffice, given the physical and economic constraints of the experiential environment. Strategies for Formulations Development: A Step-by-Step Guide Using JMP(R) is unique because it provides formulation scientists with the essential information they need in order to successfully conduct formulation studies in the chemical, biotech, and pharmaceutical industries.
| Author | : Shrikant P. Athavale |
| Publisher | : Notion Press |
| Total Pages | : 234 |
| Release | : 2018-11-27 |
| Genre | : Technology & Engineering |
| ISBN | : 1644290073 |
Download Hand Book of Rubber Formulations Book in PDF, ePub and Kindle
The core content of this book is derived from the author’s experience as a Senior Technocrat, associated with the rubber industry in the aspects of Production, R&D and new plant erection and commissioning. This book is dedicated to a variety of Rubber Starting Point Formulations that could be very useful for the rubber industry. The rubber industry is an important resource-based industry in India. Over many decades, the rubber industry has witnessed steady and strong growth. Rubber can be processed in many ways to manufacture a wide range of products. This book provides the starting point formulations that cover the manufacturing processes of rubber products such as calendaring, extrusion and molding. Thus, the book is very useful for new entrepreneurs, existing units, technical institutions and technocrats. These formulations are based on General Compounding Principles and properties such as Tensile Strength, Tear Resistance, The Crescent Tear Test, The Hardness of Rubber, Abrasion Resistance, Flex Cracking Resistance, Resilience, Heat Build-up, and Temperature Resistance. The formulations are aimed at products like Retreading Materials, Conveyor Belting, Transmission Belting and Hose, Footwear, Rubber Roller, Medical Applications, O rings and Seals, Rubber Blends and Manufacture of Latex Products.
| Author | : Lawrence A. Trissel |
| Publisher | : American Pharmacists Association (APhA) |
| Total Pages | : 456 |
| Release | : 2000 |
| Genre | : Drug stability |
| ISBN | : |
Download Trissel's Stability of Compounded Formulations Book in PDF, ePub and Kindle
"Helps readers determine whether formulated compounds will be stable for the anticipated duration of use; properly store and repackage compounded formulations; formulate in accordance with documented standards; and, counsel patients on the use and storate of comounded medications." -- Back cover.
| Author | : Feroz Jameel |
| Publisher | : John Wiley & Sons |
| Total Pages | : 986 |
| Release | : 2010-07-13 |
| Genre | : Science |
| ISBN | : 0470595876 |
Download Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals Book in PDF, ePub and Kindle
A real-world guide to the production and manufacturing of biopharmaceuticals While much has been written about the science of biopharmaceuticals, there is a need for practical, up-to-date information on key issues at all stages of developing and manufacturing commercially viable biopharmaceutical drug products. This book helps fill the gap in the field, examining all areas of biopharmaceuticals manufacturing, from development and formulation to production and packaging. Written by a group of experts from industry and academia, the book focuses on real-world methods for maintaining product integrity throughout the commercialization process, clearly explaining the fundamentals and essential pathways for all development stages. Coverage includes: Research and early development phase appropriate approaches for ensuring product stability Development of commercially viable formulations for liquid and lyophilized dosage forms Optimal storage, packaging, and shipping methods Case studies relating to therapeutic monoclonal antibodies, recombinant proteins, and plasma fractions Useful analysis of successful and failed products Formulation and Process Development Strategies for Manufacturing Biopharma-ceuticals is an essential resource for scientists and engineers in the pharmaceutical and biotech industries, for government and regulatory agencies, and for anyone with an interest in the latest developments in the field.
| Author | : Hanne Hjorth Tonnesen |
| Publisher | : CRC Press |
| Total Pages | : 450 |
| Release | : 2004-06-29 |
| Genre | : Medical |
| ISBN | : 1420023594 |
Download Photostability of Drugs and Drug Formulations, Second Edition Book in PDF, ePub and Kindle
Providing the guidance needed for formulation, handling, and quality control of photolabile drugs, Photostability of Drugs and Drug Formulations, Second Edition explores the significance of new information on drug photoreactivity in a pharmaceutical context. Completely revised and updated, with chapter authors drawn from an international panel of experts, the book supplies the background necessary for planning standardized photochemical stability studies as a part of drug development and formulation work. It contains comprehensive coverage of the physical and chemical aspects of drug photoreactivity, formulation, stability testing, and drug design/discovery in one resource. The contents have been reorganized to focus on the standardization of photostability testing of drug substances and products, in vitro photoreactivity screening of drugs, and various aspects of the formulation of photoreactive substances. The information on in vitro screening of drug photoreactivity is of great relevance for scientists who are developing and validating a set of testing protocols to address photosafety. Discussing kinetic and chemical aspects of drug photodecomposition as well as the practical problems frequently encountered in photochemical stability testing, this book helps you design a test protocol and interpret the results. Features Assists non-experts in this field design a test protocol and interpret the results Covers in vitro and in vivo aspects of interactions between drugs and light Explores the kinetic and chemical aspects of drug photodecomposition Discusses the problems frequently encountered in photochemical stability testing Provides guidance on how to address photosafety assessments and labeling requirements of potentially photoreactive drugs Highlights the practical implications of drug photodecomposition from a pharmaceutical viewpoint Offers specific guidance in photostability testing and screening of drug photoreactivity
| Author | : Shrikant P. Athavale |
| Publisher | : Notion Press |
| Total Pages | : 232 |
| Release | : 2018-10-15 |
| Genre | : Technology & Engineering |
| ISBN | : 1644292491 |
Download Hand Book of Adhesive Formulations Book in PDF, ePub and Kindle
This book is dedicated to the Adhesive Industry, especially for the Tape, Sealant, and Lamination Industry. In this book, the author has offered the Starting Point Formulations in order to manufacture various kinds of adhesives, sealants, and coating for a variety of manufacturing plants. Being an SPA Technical Advisor’s Proprietor, the author of this book has based its core content from his experience as a senior technocrat associated with the Rubber and Adhesive Tape Industry for the past 44 years in areas like Production, R&D, and setting up of new plants as well as commissioning.
