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Formal Methods for the Analysis of Biomedical Ontologies

Formal Methods for the Analysis of Biomedical Ontologies
Author: Guo-Qiang Zhang
Publisher: Springer Nature
Total Pages: 258
Release: 2022-11-08
Genre: Computers
ISBN: 3031121317

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The book synthesizes research on the analysis of biomedical ontologies using formal concept analysis, including through auditing, curation, and enhancement. As the evolution of biomedical ontologies almost inevitably involves manual work, formal methods are a particularly useful tool for ontological engineering and practice, particularly in uncovering unexpected "bugs" and content materials. The book first introduces simple but formalized strategies for discovering undesired and incoherent patterns in ontologies before exploring the application of formal concept analysis for semantic completeness. The book then turns to formal concept analysis, a classical approach used in the mathematical treatment of orders and lattices, as an ontological engineering principle, focusing on the structural property of ontologies with respect to its conformation to lattice or not (non-lattice). The book helpfully covers the development of more efficient algorithms for non-lattice detection and extraction required by exhaustive lattice/non-lattice analysis. The book goes on to highlight the power and utility of uncovering non-lattice structure for debugging ontologies and describes methods that leverage the linguistic information in concept names (labels) for ontological analysis. It also addresses visualization and performance evaluation issues before closing with an overview and forward-looking perspectives on the field. This book is intended for graduate students and researchers interested in biomedical ontologies and their applications. It can be a useful supplement for courses on knowledge representation and engineering and also provide readers with a reference for related scientific publications and literature to assist in identifying potential research topics. All mathematical concepts and notations used in this book can be found in standard discrete mathematics textbooks, and the appendix at the end of the book provides a list of key ontological resources, as well as annotated non-lattice and lattice examples that were discovered using the authors' methods, demonstrating how "bugs are fixed" by converting non-lattices to lattices with minimal edit changes.


Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications

Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications
Author: Tiziana Margaria
Publisher: Springer
Total Pages: 661
Release: 2014-09-26
Genre: Computers
ISBN: 3662452316

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The two-volume set LNCS 8802 and LNCS 8803 constitutes the refereed proceedings of the 6th International Symposium on Leveraging Applications of Formal Methods, Verification and Validation, ISoLA 2014, held in Imperial, Corfu, Greece, in October 2014. The total of 67 full papers was carefully reviewed and selected for inclusion in the proceedings. Featuring a track introduction to each section, the papers are organized in topical sections named: evolving critical systems; rigorous engineering of autonomic ensembles; automata learning; formal methods and analysis in software product line engineering; model-based code generators and compilers; engineering virtualized systems; statistical model checking; risk-based testing; medical cyber-physical systems; scientific workflows; evaluation and reproducibility of program analysis; processes and data integration in the networked healthcare; semantic heterogeneity in the formal development of complex systems. In addition, part I contains a tutorial on automata learning in practice; as well as the preliminary manifesto to the LNCS Transactions on the Foundations for Mastering Change with several position papers. Part II contains information on the industrial track and the doctoral symposium and poster session.


Formal Methods for Managing and Processing Ontology Alignments

Formal Methods for Managing and Processing Ontology Alignments
Author: Marcin Pietranik
Publisher: CRC Press
Total Pages: 210
Release: 2024-10-07
Genre: Computers
ISBN: 1040133274

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Ontologies are formal knowledge representation methods that can provide means for a shared understanding of a given domain. To enable meaningful communication and interoperability between two or more information systems that utilize independently created ontologies, a bridge between them is necessary, often referred to as an ontology alignment. Formal Methods for Managing and Processing Ontology Alignments provides complete ontology alignment lifecycle, including modelling, methods, and maintenance processes. Summarizing the author's research from the past ten years, this book consolidates findings previously published in prestigious international journals and presented at leading conferences. Each chapter is designed to be self-contained, allowing readers to approach the material modularly. The text introduces basic mathematical concepts, and later chapters build upon these foundations, but each focuses on specific aspects of ontology alignment, making the content accessible and easy to follow. Key Features Includes formal definitions of ontologies and ontology alignment along with a set of methods for providing semantics of attributes and relations. Provides application of fuzzy logic in the task of ontology alignment. Contains methods of managing the evolution of ontologies and their alignments. Proposes novel methods of assessing the quality ontology alignment. Situated in the fields of knowledge representation and semantic technologies, this book is an invaluable resource for both academic researchers and practitioners, as well as students looking to deepen their understanding.


Implicit and Explicit Semantics Integration in Proof-Based Developments of Discrete Systems

Implicit and Explicit Semantics Integration in Proof-Based Developments of Discrete Systems
Author: Yamine Ait-Ameur
Publisher: Springer Nature
Total Pages: 345
Release: 2020-07-27
Genre: Computers
ISBN: 9811550549

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This book addresses mechanisms for reducing model heterogeneity induced by the absence of explicit semantics expression in the formal techniques used to specify design models. More precisely, it highlights the advances in handling both implicit and explicit semantics in formal system developments, and discusses different contributions expressing different views and perceptions on the implicit and explicit semantics. The book is based on the discussions at the Shonan meeting on this topic held in 2016, and includes contributions from the participants summarising their perspectives on the problem and offering solutions. Divided into 5 parts: domain modelling, knowledge-based modelling, proof-based modelling, assurance cases, and refinement-based modelling, and offers inspiration for researchers and practitioners in the fields of formal methods, system and software engineering, domain knowledge modelling, requirement analysis, and explicit and implicit semantics of modelling languages.


Leveraging Applications of Formal Methods, Verification and Validation. Technologies for Mastering Change

Leveraging Applications of Formal Methods, Verification and Validation. Technologies for Mastering Change
Author: Tiziana Margaria
Publisher: Springer
Total Pages: 564
Release: 2014-09-26
Genre: Computers
ISBN: 3662452340

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The two-volume set LNCS 8802 and LNCS 8803 constitutes the refereed proceedings of the 6th International Symposium on Leveraging Applications of Formal Methods, Verification and Validation, ISoLA 2014, held in Imperial, Corfu, Greece, in October 2014. The total of 67 full papers was carefully reviewed and selected for inclusion in the proceedings. Featuring a track introduction to each section, the papers are organized in topical sections named: evolving critical systems; rigorous engineering of autonomic ensembles; automata learning; formal methods and analysis in software product line engineering; model-based code generators and compilers; engineering virtualized systems; statistical model checking; risk-based testing; medical cyber-physical systems; scientific workflows; evaluation and reproducibility of program analysis; processes and data integration in the networked healthcare; semantic heterogeneity in the formal development of complex systems. In addition, part I contains a tutorial on automata learning in practice; as well as the preliminary manifesto to the LNCS Transactions on the Foundations for Mastering Change with several position papers. Part II contains information on the industrial track and the doctoral symposium and poster session.


Formal Ontology in Information Systems

Formal Ontology in Information Systems
Author: Carola Eschenbach
Publisher: IOS Press
Total Pages: 340
Release: 2008
Genre: Computers
ISBN: 1586039237

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"Since its start ten years ago, the International Conference in Formal Ontology on Information Systems (FOIS) has explored the multiple perspectives on the notion of ontology that have arisen from such diverse research communities as philosophy, logic, computer science, cognitive science, linguistics, and various scientific domains. As ontologies have been applied in new and exciting domains such as the World Wide Web, bioinformatics, and geographical information systems, it has become evident that there is a need for ontologies that have been developed with solid theoretical foundations based on philosophical, linguistic and logical analysis. Similarly, there is also a need for theoretical research that is driven by the issues that have been raised by recent work in the more applied domains. FOIS is intended to be a forum in which to explore this interplay between the theoretical insights of formal ontology and their application to information systems and emerging semantic technologies. Themes emerging from this volume give a snapshot of current issues within the fields of formal ontology and ontological engineering, as well providing a glimpse of future research directions."--BOOK JACKET.


Formal Concept Analysis

Formal Concept Analysis
Author: Sébastien Ferré
Publisher: Springer Science & Business Media
Total Pages: 350
Release: 2009-05-12
Genre: Computers
ISBN: 3642018149

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This book constitutes the refereed proceedings of the 7th International Conference on Formal Concept Analysis, ICFCA 2009, held in Darmstadt, Germany, in May 2009. The 15 revised full papers presented were carefully reviewed and selected from 29 submissions for inclusion in the book. The papers comprise state of the art research and present new results in Formal Concept Analysis and related fields. These results range from theoretical novelties to advances in FCA-related algorithmic issues, as well as application domains of FCA such as data visualization, information retrieval, machine learning, data analysis and knowledge management.


Formal Ontologies Meet Industry

Formal Ontologies Meet Industry
Author: R. Ferrario
Publisher: IOS Press
Total Pages: 144
Release: 2009-08-21
Genre: Business & Economics
ISBN: 1607504588

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This book is a collection of papers addressing the multi-shaped character of knowledge, new studies and applications in the field of ontology and semantic technology. The semantic dimension of information plays an increasingly central role in a networked, knowledge-centred economy and the need to encode information into computer systems has led to a bias towards Knowledge Engineering (KE) solutions as opposed to Knowledge Management (KM). Although the intersection between KE and KM has led to a general improvement of information systems, the overlap between these two fields has tended to eclipse interest in genuine knowledge processes. For this reason, the fourth FOMI workshop was held to coincide with the 10th European Conference of Knowledge Management (ECKM), with the explicit aim of bringing together KR and KM (sub)-communities, providing a platform for discussion of these topics. Subjects covered include: the evolution of ontologies in accordance with the evolution of the domain they are designed for; the study of the notions of functional composition and decomposition; modular ontologies for architecture; ontology infrastructure for electromagnetics; ontology of beliefs; enterprise modelling; the application of ontology-based methodologies and techniques to knowledge management issues; ontologies for standards and domain ontologies for biomedicine. The double focus on methodological and applicative issues represents the main feature of these FOMI 2009 articles. This comprehensive perspective will advance progress towards new frontiers in information systems and knowledge management, where research and development in formal ontology will play a leading role.


Building Ontologies with Basic Formal Ontology

Building Ontologies with Basic Formal Ontology
Author: Robert Arp
Publisher: MIT Press
Total Pages: 245
Release: 2015-07-31
Genre: Science
ISBN: 0262527812

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An introduction to the field of applied ontology with examples derived particularly from biomedicine, covering theoretical components, design practices, and practical applications. In the era of “big data,” science is increasingly information driven, and the potential for computers to store, manage, and integrate massive amounts of data has given rise to such new disciplinary fields as biomedical informatics. Applied ontology offers a strategy for the organization of scientific information in computer-tractable form, drawing on concepts not only from computer and information science but also from linguistics, logic, and philosophy. This book provides an introduction to the field of applied ontology that is of particular relevance to biomedicine, covering theoretical components of ontologies, best practices for ontology design, and examples of biomedical ontologies in use. After defining an ontology as a representation of the types of entities in a given domain, the book distinguishes between different kinds of ontologies and taxonomies, and shows how applied ontology draws on more traditional ideas from metaphysics. It presents the core features of the Basic Formal Ontology (BFO), now used by over one hundred ontology projects around the world, and offers examples of domain ontologies that utilize BFO. The book also describes Web Ontology Language (OWL), a common framework for Semantic Web technologies. Throughout, the book provides concrete recommendations for the design and construction of domain ontologies.


Formal Ontology in Information Systems

Formal Ontology in Information Systems
Author: Antony Galton
Publisher: IOS Press
Total Pages: 444
Release: 2010
Genre: Computers
ISBN: 1607505347

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Ontology began life in ancient times as a fundamental part of philosophical enquiry concerned with the analysis and categorisation of what exists. In recent years, the subject has taken a practical turn with the advent of complex computerised information systems which are reliant on robust and coherent representations of their subject matter. The systematisation and elaboration of such representations and their associated reasoning techniques constitute the modern discipline of formal ontology, which is now being applied to such diverse domains as artificial intelligence, computational linguistics, bioinformatics, GIS, knowledge engineering, information retrieval and the Semantic Web. Researchers in all these areas are becoming increasingly aware of the need for serious engagement with ontology, understood as a general theory of the types of entities and relations making up their respective domains of enquiry, to provide a solid foundation for their work. The conference series Formal Ontology in Information Systems (FOIS) provides a meeting point for researchers from these and other disciplines with an interest in formal ontology, where both theoretical issues and concrete applications can be explored in a spirit of genuine interdisciplinarity. This volume contains the proceedings of the sixth FOIS conference, held in Toronto, Canada, during 11-14 May 2010, including invited talks by Francis Jeffry Pelletier, John Bateman, and Alan Rector and the 28 peer-reviewed submissions selected for presentation at the conference, ranging from foundational issues to more application-oriented topics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences