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Protein Folding

Protein Folding
Author: Tony R. Obalinsky
Publisher: Nova Publishers
Total Pages: 294
Release: 2006
Genre: Science
ISBN: 9781594548352

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Proteins are one of the most basic components of all living cells and therefore serve a vital purpose in the cells of animals, plants and bacteria. They are comprised of chains of amino acids, which are held together by ribosome. These chains have many different patterns, which are known as `folds.' These folds are complicated, and therefore susceptible to irregularities that are known to be the source of many diseases. Cystic fibrosis, mad cow disease, Alzheimer's disease, emphysema and others are all initiated by improper protein folds. It is clear that, improving our understanding of protein folding is a key to fighting these diseases. This book presents recently performed research from around the world on this important subject.


Protein Folding

Protein Folding
Author: Cláudio M. Gomes
Publisher: Springer
Total Pages: 63
Release: 2019-02-25
Genre: Science
ISBN: 331900882X

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This snapshot volume is designed to provide a smooth entry into the field of protein folding. Presented in a concise manner, each section introduces key concepts while providing a brief overview of the relevant literature. Outlook subsections will pinpoint specific aspects related to emerging methodologies, concepts and trends.


On Folding

On Folding
Author: Michael Friedman
Publisher: transcript Verlag
Total Pages: 243
Release: 2016-05-31
Genre: Philosophy
ISBN: 3839434041

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It is only recently, with the increasing interest in origami and folding in natural sciences and the humanities, that the fold as a new conception in a whole range of disciplines has begun to be conceived in a broader way. Folding as a material and structural process offers a new methodology to think about the close relationship of matter, form and code. It henceforth crosses out old dichotomies, such as the organic and the inorganic or nature and technology, and blurs the boundaries between experimental, conceptual and historical approaches. This anthology aims to unfold this new interdisciplinary field and its disciplinary impact, ranging from materials science, biology, architecture, and mathematics to literature and philosophy.


Folding and Self-assembly of Biological Macromolecules

Folding and Self-assembly of Biological Macromolecules
Author: Noah Hardy
Publisher: World Scientific
Total Pages: 424
Release: 2004
Genre: Mathematics
ISBN: 9789812703057

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Organized by Alessandra Carbone ( IHeS, Bures-sur-Yvette, France ) Organized by Misha Gromov ( IHeS, Bures-sur-Yvette, France ) Organized by Fran ois K(r)p s ( CNRS-Genopole-, evry, France ) Organized by Eric Westhof ( Universit(r) Louis-Pasteur, Strasbourg, France ). This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers OCo and audience interaction OCo are edited and illustrated versions of the transcribed oral presentations. The proceedings have been selected for coverage in: . OCo Biochemistry & Biophysics Citation Index(tm). OCo Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings). OCo CC Proceedings OCo Biomedical, Biological & Agricultural Sciences. Contents: Evolution-Based Genome Analysis: An Alternative to Analyze Folding and Function in Proteins (S Benner); Conformation of Charged Polymers: Polyelectrolytes and Polyampholytes (J-F Joanny); Statistically Derived Rules for RNA Folding (M Zuker); Experimental Approaches to RNA Folding (S Woodson); Some Questions Concerning RNA Folding (F Michel); RNA Folding in Ribosome Assembly (J R Williamson); From RNA Sequences to Folding Pathways and Structures: A Perspective (H Isamber t); An Evolutionary Perspective on the Determinants of Protein Function and Assembly (O Lichtarg e); Some Residues are more Equal than Others: Application to Protein Classification and Structure Prediction (A Kister & I Gelfan d); Structure-Function Relationships in Polymerases (M Delarue); The Protein-Folding Nucleus: From Simple Models to Real Proteins (L Mirn y); Chaperonin-Mediated Protein Folding (D Thirumalai); Virus Assembly and Maturation (J E Johnson); The Animal in the Machine: Is There a Geometric Program in the Genetic Program? (A Danchin). Readership: Researchers, academics and graduate students in structural biology, cellular and molecular biology, biophysics, biochemistry and biomathematics/bioinformatics."


Protein Folding

Protein Folding
Author: C. M. Dobson
Publisher: Cambridge University Press
Total Pages: 128
Release: 1995
Genre: Medical
ISBN: 9780521576369

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Discusses the molecular mechanisms controlling protein folding in vivo and in vitro.


Styles Of Folding

Styles Of Folding
Author: Arvind Johnson
Publisher: Elsevier
Total Pages: 425
Release: 2012-12-02
Genre: Science
ISBN: 0444601430

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Styles of Folding: Mechanics and Mechanisms of Folding of Natural Elastic Materials, Developments in Geotectonics 11, provides an introduction to theoretical underpinnings of folds in rocks. The book begins with a review of studies which have been most significant to the development of current understanding of folds. It then turns to the development of a theory of folding of multilayered elastic materials. It presents the derivation of linearized equations that describe the incremental deformation of materials with memory; these equations are then used to solve for wavelengths of sinusoidal folds in single layers and multilayers. A theory of kink folding in elastic multilayers is introduced based on the mechanism of plastic yielding between layers. The chapters also include analyses of folds in the Carmel Formation at Arches National Monument in Utah; asymmetric folds in interbedded cherts and shales of the Franciscan Complex; and some folds in Tertiary rocks in the Coast Ranges of California. Finally, the most important mechanisms of folding recognized thus far are summarized for multilayered materials with a wide range of properties.


Thrust Fault-Related Folding

Thrust Fault-Related Folding
Author: Ken McClay
Publisher: AAPG
Total Pages: 404
Release: 2011-10-01
Genre: Science
ISBN: 0891813764

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From Globular Proteins to Amyloids

From Globular Proteins to Amyloids
Author: Irena Roterman-Konieczna
Publisher: Elsevier
Total Pages: 280
Release: 2019-10-15
Genre: Medical
ISBN: 0081029829

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From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations. Introduces basic rules for protein folding, along with the conditions that result in misfolding Presents research that lies in treating the aqueous environment as a continuum rather than a set of individual water molecules (i.e. the classic representation) Provides practical applications for helping the prevention of amyloidosis and improving drug design


Fold and Thrust Belts

Fold and Thrust Belts
Author: J.A. Hammerstein
Publisher: Geological Society of London
Total Pages: 455
Release: 2020-10-14
Genre: Science
ISBN: 1786204479

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The outer parts of collision mountain belts are commonly represented by fold and thrust belts. Major advances in understanding these tectonic settings have arisen from regional studies that integrate diverse geological information in quests to find and produce hydrocarbons. Drilling has provided tests of subsurface forecasts, challenging interpretation strategies and structural models. This volume contains 19 papers that illustrate a diversity of methods and approaches together with case studies from Europe, the Middle East and the Asia-Pacific region. Collectively they show that appreciating diversity is key for developing better interpretations of complex geological structures in the subsurface – endeavours that span applications beyond the development of hydrocarbons.


Folding and Fracturing of Rocks

Folding and Fracturing of Rocks
Author: C.E. Bond
Publisher: Geological Society of London
Total Pages: 353
Release: 2020-01-02
Genre: Science
ISBN: 1786204290

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This Special Publication is a celebration of research into the Folding and Fracturing of Rocks to mark the 50th anniversary of the publication of the seminal textbook by J. G. Ramsay. Folding and Fracturing of Rocks summarised the key structural geology concepts of the time. Through his numerical and geometric focus John pioneered and provided solutions to understanding the processes leading to the folding and fracturing of rocks. His strong belief that numerical and geometric solutions, to understanding crustal processes, should be tested against field examples added weight and clarity to his work. The basic ideas and solutions presented in the text are as relevant now as they were 50 years ago, and this collection of papers celebrates John’s contribution to structural geology. The papers explore the lasting impact of John and his work, they present case studies and a modern understanding of the process documented in the Folding and Fracturing of Rocks.