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| Author | : Abraham J. Domb |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 700 |
| Release | : 2014-02-17 |
| Genre | : Medical |
| ISBN | : 1461494346 |
Download Focal Controlled Drug Delivery Book in PDF, ePub and Kindle
The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
| Author | : Emmanuel C. Opara |
| Publisher | : CRC Press |
| Total Pages | : 526 |
| Release | : 2020-02-28 |
| Genre | : Medical |
| ISBN | : 0429582757 |
Download Controlled Drug Delivery Systems Book in PDF, ePub and Kindle
This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.
| Author | : Juergen Siepmann |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 593 |
| Release | : 2011-12-15 |
| Genre | : Medical |
| ISBN | : 1461408814 |
Download Fundamentals and Applications of Controlled Release Drug Delivery Book in PDF, ePub and Kindle
This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.
| Author | : Filippo Rossi |
| Publisher | : Springer |
| Total Pages | : 107 |
| Release | : 2016-01-19 |
| Genre | : Technology & Engineering |
| ISBN | : 3319022881 |
Download Controlled Drug Delivery Systems Book in PDF, ePub and Kindle
This book offers a state-of-the-art overview of controlled drug delivery systems, covering the most important innovative applications. The principles of controlled drug release and the mechanisms involved in controlled release are clearly explained. The various existing polymeric drug delivery systems are reviewed, and new frontiers in material design are examined in detail, covering a wide range of polymer modification techniques. The concluding chapter is a case study focusing on use of a drug-eluting stent. The book is designed to provide the reader with a complete understanding of the mechanisms and design of controlled drug delivery systems, and to this end includes numerous step-by-step tutorials. It illustrates how chemical engineers can advance medical care by designing polymeric delivery systems that achieve either temporal or spatial control of drug delivery and thus ensure more effective therapy that eliminates the potential for both under- and overdosing.
| Author | : Kinam Park |
| Publisher | : |
| Total Pages | : 656 |
| Release | : 1997 |
| Genre | : Medical |
| ISBN | : |
Download Controlled Drug Delivery Book in PDF, ePub and Kindle
This volume discusses the challenges of creating controlled release dosage forms that will deliver new therapeutic agents based on high-molecular-weight molecules. It examines strategies for delivering drugs through resistant biological barriers and surveys a variety of topics, including drug targeting, self-regulated drug delivery, protein drug delivery, biosensors, cell and tissue engineering, new biomaterials, modeling methods, pharmacokinetics, and U.S. federal regulations.
| Author | : Xiaoling Li |
| Publisher | : McGraw Hill Professional |
| Total Pages | : 453 |
| Release | : 2005-11-24 |
| Genre | : Technology & Engineering |
| ISBN | : 0071588833 |
Download Design of Controlled Release Drug Delivery Systems Book in PDF, ePub and Kindle
The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.
| Author | : Verma, Shekhar |
| Publisher | : IGI Global |
| Total Pages | : 395 |
| Release | : 2022-03-25 |
| Genre | : Medical |
| ISBN | : 1799889092 |
Download Advancements in Controlled Drug Delivery Systems Book in PDF, ePub and Kindle
The many drawbacks of conventional dosage forms and delivery systems are overcome by designing and developing controlled release drug delivery systems, and pharmaceutical and other scientists have carried out extensive and intensive investigations in the field to explore their applications. A controlled-release drug formulation can improve product efficacy and extend patent protection. As controlled drug delivery systems continue to play a vital role in delivering various types of therapeutic agents in a controlled manner, researchers are only just scratching the surface of their full potential. Advancements in Controlled Drug Delivery Systems supplies information on translating the physicochemical properties of drugs into drug delivery systems, explores how drugs are administered via various routes, and discusses recent advancements in the fabrication and development of controlled drug delivery systems. It also underlines the methodology of controlled drug delivery system preparation and the significance, disadvantages, detailed classifications, and relevant examples. Covering topics such as machine learning and oral-controlled drug delivery, this book is ideal for pharmacists, healthcare professionals, researchers, academicians, research centers, health units, students, and pharmaceutical and scientific laboratories.
| Author | : Vasant V. Ranade |
| Publisher | : CRC Press |
| Total Pages | : 464 |
| Release | : 2003-08-26 |
| Genre | : Medical |
| ISBN | : 1420040146 |
Download Drug Delivery Systems Book in PDF, ePub and Kindle
Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both
| Author | : Agis F. Kydonieus |
| Publisher | : CRC Press |
| Total Pages | : 568 |
| Release | : 2017-10-02 |
| Genre | : Medical |
| ISBN | : 1351406884 |
Download Treatise on Controlled Drug Delivery Book in PDF, ePub and Kindle
An introductory but detailed treatise which includes some 1,000 references and solved examples and end-of-chapter problems, making it useful to both students and practitioners. The pharmokinetics, pharmacodynamics, and biological and biopharmaceutical parameters pertinent to each route of administra
| Author | : Kinam Park |
| Publisher | : |
| Total Pages | : 558 |
| Release | : 2000 |
| Genre | : Medical |
| ISBN | : |
Download Controlled Drug Delivery Book in PDF, ePub and Kindle
Controlled Drug Delivery examines the current state of drug deliverytechnologies and discusses the future directions of drug delivery development.Topics include advances for increasing the uptake of orally delivered drugs,modulating blood levels for better drug safety/efficacy profiles, targetingdrugs and genes for cellular and intracellular delivery, improving the deliveryof poorly soluble drugs and recent advances in polymer-based drug deliverytechnologies.
