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| Author | : Igor M. Rouzine |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 322 |
| Release | : 2023-09-18 |
| Genre | : Mathematics |
| ISBN | : 3110697386 |
| Author | : Eugene V. Koonin |
| Publisher | : FT Press |
| Total Pages | : 530 |
| Release | : 2011-06-23 |
| Genre | : Science |
| ISBN | : 013262317X |
The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.
| Author | : Esteban Domingo |
| Publisher | : Academic Press |
| Total Pages | : 426 |
| Release | : 2019-11-06 |
| Genre | : Science |
| ISBN | : 0128163321 |
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
| Author | : C. Neal Stewart, Jr. |
| Publisher | : John Wiley & Sons |
| Total Pages | : 554 |
| Release | : 2012-12-13 |
| Genre | : Science |
| ISBN | : 1118589483 |
Designed to inform and inspire the next generation of plant biotechnologists Plant Biotechnology and Genetics explores contemporary techniques and applications of plant biotechnology, illustrating the tremendous potential this technology has to change our world by improving the food supply. As an introductory text, its focus is on basic science and processes. It guides students from plant biology and genetics to breeding to principles and applications of plant biotechnology. Next, the text examines the critical issues of patents and intellectual property and then tackles the many controversies and consumer concerns over transgenic plants. The final chapter of the book provides an expert forecast of the future of plant biotechnology. Each chapter has been written by one or more leading practitioners in the field and then carefully edited to ensure thoroughness and consistency. The chapters are organized so that each one progressively builds upon the previous chapters. Questions set forth in each chapter help students deepen their understanding and facilitate classroom discussions. Inspirational autobiographical essays, written by pioneers and eminent scientists in the field today, are interspersed throughout the text. Authors explain how they became involved in the field and offer a personal perspective on their contributions and the future of the field. The text's accompanying CD-ROM offers full-color figures that can be used in classroom presentations with other teaching aids available online. This text is recommended for junior- and senior-level courses in plant biotechnology or plant genetics and for courses devoted to special topics at both the undergraduate and graduate levels. It is also an ideal reference for practitioners.
| Author | : George Dassios |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 192 |
| Release | : 2020-06-08 |
| Genre | : Mathematics |
| ISBN | : 3110545780 |
Electroencephalography and magnetoencephalography are the two most efficient techniques to study the functional brain. This book completely aswers the fundamental mathematical question of uniqueness of the representations obtained using these techniques, and also covers many other concrete results for special geometric models of the brain, presenting the research of the authors and their groups in the last two decades.
| Author | : Siddhartha Mukherjee |
| Publisher | : Simon and Schuster |
| Total Pages | : 624 |
| Release | : 2011-08-09 |
| Genre | : Health & Fitness |
| ISBN | : 1439170916 |
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
| Author | : Günther Witzany |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 432 |
| Release | : 2012-11-13 |
| Genre | : Science |
| ISBN | : 940074899X |
A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.
| Author | : Piotr Biler |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 231 |
| Release | : 2019-12-02 |
| Genre | : Mathematics |
| ISBN | : 3110599538 |
The Keller-Segel model for chemotaxis is a prototype of nonlocal systems describing concentration phenomena in physics and biology. While the two-dimensional theory is by now quite complete, the questions of global-in-time solvability and blowup characterization are largely open in higher dimensions. In this book, global-in-time solutions are constructed under (nearly) optimal assumptions on initial data and rigorous blowup criteria are derived.
| Author | : Rob Wallace |
| Publisher | : NYU Press |
| Total Pages | : 456 |
| Release | : 2016-06-30 |
| Genre | : Business & Economics |
| ISBN | : 1583675906 |
The first collection to explore infectious disease, agriculture, economics, and the nature of science together Thanks to breakthroughs in production and food science, agribusiness has been able to devise new ways to grow more food and get it more places more quickly. There is no shortage of news items on hundreds of thousands of hybrid poultry—each animal genetically identical to the next—packed together in megabarns, grown out in a matter of months, then slaughtered, processed and shipped to the other side of the globe. Less well known are the deadly pathogens mutating in, and emerging out of, these specialized agro-environments. In fact, many of the most dangerous new diseases in humans can be traced back to such food systems, among them Campylobacter, Nipah virus, Q fever, hepatitis E, and a variety of novel influenza variants. Agribusiness has known for decades that packing thousands of birds or livestock together results in a monoculture that selects for such disease. But market economics doesn't punish the companies for growing Big Flu—it punishes animals, the environment, consumers, and contract farmers. Alongside growing profits, diseases are permitted to emerge, evolve, and spread with little check. “That is,” writes evolutionary biologist Rob Wallace, “it pays to produce a pathogen that could kill a billion people.” In Big Farms Make Big Flu, a collection of dispatches by turns harrowing and thought-provoking, Wallace tracks the ways influenza and other pathogens emerge from an agriculture controlled by multinational corporations. Wallace details, with a precise and radical wit, the latest in the science of agricultural epidemiology, while at the same time juxtaposing ghastly phenomena such as attempts at producing featherless chickens, microbial time travel, and neoliberal Ebola. Wallace also offers sensible alternatives to lethal agribusiness. Some, such as farming cooperatives, integrated pathogen management, and mixed crop-livestock systems, are already in practice off the agribusiness grid. While many books cover facets of food or outbreaks, Wallace's collection appears the first to explore infectious disease, agriculture, economics and the nature of science together. Big Farms Make Big Flu integrates the political economies of disease and science to derive a new understanding of the evolution of infections. Highly capitalized agriculture may be farming pathogens as much as chickens or corn.
| Author | : John Mackenzie |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 423 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642594034 |
Japanese encephalitis and West Nile viruses are members of the Japanese encephalitis serological group of the genus Flavivirus and therefore closely related genetically and antigenically. They share a number of properties, including the use of birds as their major wildlife maintenance host and Culicine mosquitoes for transmission, and they are both associated with severe human disease, as well as fatal infections in horses. The emergence of these two viruses, and their well-established propensity to colonise new areas, make it timely to re-examine their ecology, biology, molecular structure, replication and epidemiology, and these therefore provide the focus of this volume.
