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Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 3

Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 3
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 45
Release: 2023-10-23
Genre: Medical
ISBN: 9240021264

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Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response; - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. This module is about using WGS in routine surveillance of foodborne diseases. It is meant for countries experienced in laboratory-based surveillance of foodborne pathogens. WGS can be implemented where subtyping foodborne pathogens or replacing traditional typing methods is being considered. Routine surveillance includes outbreak detection, monitoring trends over time, and using WGS for AMR and virulence factor monitoring.


Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 2

Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 2
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 70
Release: 2023-10-19
Genre: Medical
ISBN: 9240021248

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Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response; - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. This module discusses how WGS can be used to support foodborne disease outbreak investigations. It is meant for countries in the initial stages of laboratory-based surveillance for selected foodborne pathogens. The module describes how WGS can be used in the investigation of outbreaks detected by existing surveillance systems.


Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 1

Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 1
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 78
Release: 2023-10-19
Genre: Medical
ISBN: 9240021221

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Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response, - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. The present module introduces WGS and its relevance to foodborne diseases; it defines the minimum capacities needed before a country can implement WGS for outbreak investigations and routine surveillance; and includes a section to assist countries in selecting an option for implementing WGS within their existing surveillance and response system.


Applied Genomics of Foodborne Pathogens

Applied Genomics of Foodborne Pathogens
Author: Xiangyu Deng
Publisher: Springer
Total Pages: 213
Release: 2017-01-23
Genre: Technology & Engineering
ISBN: 3319437518

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This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.


CDC Yellow Book 2020

CDC Yellow Book 2020
Author: CENTERS FOR DISEASE CONTROL AND PREVENTION. (CDC)
Publisher: Oxford University Press, USA
Total Pages: 721
Release: 2019-06-11
Genre: Medical
ISBN: 0190065974

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The definitive reference for travel medicine, updated for 2020! "A beloved travel must-have for the intrepid wanderer." -Publishers Weekly "A truly excellent and comprehensive resource." -Journal of Hospital Infection The CDC Yellow Book offers everything travelers and healthcare providers need to know for safe and healthy travel abroad. This 2020 edition includes: · Country-specific risk guidelines for yellow fever and malaria, including expert recommendations and 26 detailed, country-level maps · Detailed maps showing distribution of travel-related illnesses, including dengue, Japanese encephalitis, meningococcal meningitis, and schistosomiasis · Guidelines for self-treating common travel conditions, including altitude illness, jet lag, motion sickness, and travelers' diarrhea · Expert guidance on food and drink precautions to avoid illness, plus water-disinfection techniques for travel to remote destinations · Specialized guidelines for non-leisure travelers, study abroad, work-related travel, and travel to mass gatherings · Advice on medical tourism, complementary and integrative health approaches, and counterfeit drugs · Updated guidance for pre-travel consultations · Advice for obtaining healthcare abroad, including guidance on different types of travel insurance · Health insights around 15 popular tourist destinations and itineraries · Recommendations for traveling with infants and children · Advising travelers with specific needs, including those with chronic medical conditions or weakened immune systems, health care workers, humanitarian aid workers, long-term travelers and expatriates, and last-minute travelers · Considerations for newly arrived adoptees, immigrants, and refugees Long the most trusted book of its kind, the CDC Yellow Book is an essential resource in an ever-changing field -- and an ever-changing world.


Foodborne Disease Outbreaks

Foodborne Disease Outbreaks
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 157
Release: 2008
Genre: Business & Economics
ISBN: 9241547227

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"These guidelines have been written for public health practitioners, food and health inspectors, district and national medical officers, laboratory personnel and others who may undertake or participate in the investigation and control of foodborne disease outbreaks."--P. 4 of cover.


A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 200
Release: 2011-08-26
Genre: Medical
ISBN: 0309212197

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Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.


Emerging foodborne pathogens

Emerging foodborne pathogens
Author: Yasmine Motarjemi
Publisher: CRC Press
Total Pages: 664
Release: 2006-06-09
Genre: Technology & Engineering
ISBN: 9780849334290

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Developments such as the increasing globalization of the food industry, constant innovations in technologies and products, and changes in the susceptibility of populations to disease have all highlighted the problem of emerging pathogens, either newly discovered through more sensitive analytical methods, linked for the first time to disease in humans, or newly associated with a particular food. Designed for microbiologists and quality assurance professionals and for government and academic food safety scientists, this timely reference discusses ways of identifying emerging pathogens and includes chapters on individual pathogens, their epidemiology, methods of detection, and means of control.