Evolution Of Hox Gene Expression And Function And The Effect On Limb Specification In Arthropods PDF Download
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Author | : Cheryl Chih-Jui Hsia |
Publisher | : |
Total Pages | : 105 |
Release | : 2007 |
Genre | : |
ISBN | : |
Download Evolution of Hox Gene Expression and Function and the Effect on Limb Specification in Arthropods Book in PDF, ePub and Kindle
Many common sets of genes are used to generate diverse animal body plans. One set of these genes are the Hox genes, transcription factors that specify segmental identity along the anterior-posterior axis of animals in early development. Many studies have been carried out to uncover how the evolution of Hox genes and Hox gene function may have precipitated the evolution of diverse body plans. I carried out functional assays in Drosophila melanogaster embryos to explore whether changes in protein sequence may have facilitated the divergence of six-legged insects from multi-legged crustaceans. I developed fluorescent immunohistochemistry and double in situ hybridization methods in the crustacean, Artemia franciscana, to further clarify the HOX expression patterns in the trunk. From these studies, I found an example of a Hox gene capable of homeotic function, but inhibited from expression and presumably, inhibited from conferring segmental identity. This loss of segment identity function may contribute to the overall morphological body plan of Artemia to ensure the development of limbs throughout the trunk.
Author | : Spyros Papageorgiou |
Publisher | : Springer Science & Business Media |
Total Pages | : 158 |
Release | : 2007-08-28 |
Genre | : Medical |
ISBN | : 0387689907 |
Download HOX Gene Expression Book in PDF, ePub and Kindle
Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.
Author | : Jennifer K. Grenier |
Publisher | : |
Total Pages | : 180 |
Release | : 2000 |
Genre | : |
ISBN | : |
Download The Origin and Evolution of Arthropod Hox Genes Book in PDF, ePub and Kindle
Author | : Gerhard Scholtz |
Publisher | : CRC Press |
Total Pages | : 324 |
Release | : 2003-06-01 |
Genre | : Science |
ISBN | : 9789058096371 |
Download Evolutionary Developmental Biology of Crustacea Book in PDF, ePub and Kindle
Crustaceans, due to the great diversity of their body organization, segmentation patterns, tagmatization, limb types, larval forms, cleavage, and gastrulation modes, are highly desirable for the study of questions at the interface of evolution and development. Modern interest in evolutionary developmental biology (evo-devo) rests on the molecular genetic approach and a variety of molecular techniques have proven fruitful when performed on crustaceans. Evolutionary Developmental Biology of Crustacea presents a comprehensive treatment of all aspects of the field, beginning with a discussion of the implications of the typological Bauplan and phylum concepts versus historical concepts such as ground pattern and monophylum for the formulation of conceptual questions in evo-devo. Following this, the authors present the results of Hox gene expression in various crustacean taxa, aspects of segment formation at the cellular and genetic levels, the formation of segmental structures such as neurons, ganglia, and limbs, and the role of morphological ontogenetic characters in resolving phylogenetic relationships. By covering so many general aspects of crustacean development, morphology, and evolution, Evolutionary Developmental Biology of Crustacea serves as an indispensable reference for developmental and evolutionary biologists investigating the role of genetics in evolution and development.
Author | : Michael Akam |
Publisher | : |
Total Pages | : 256 |
Release | : 1994 |
Genre | : Science |
ISBN | : |
Download The Evolution of Developmental Mechanisms Book in PDF, ePub and Kindle
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 347 |
Release | : 2000-11-21 |
Genre | : Nature |
ISBN | : 0309171806 |
Download Scientific Frontiers in Developmental Toxicology and Risk Assessment Book in PDF, ePub and Kindle
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author | : National Academy of Sciences |
Publisher | : |
Total Pages | : 388 |
Release | : 2007 |
Genre | : Science |
ISBN | : |
Download In the Light of Evolution Book in PDF, ePub and Kindle
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Author | : Eric H. Davidson |
Publisher | : Elsevier |
Total Pages | : 274 |
Release | : 2001-01-24 |
Genre | : Science |
ISBN | : 0080525598 |
Download Genomic Regulatory Systems Book in PDF, ePub and Kindle
The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist. * Contents Include* Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression* Regulation of Direct Cell-Type Specification in Early Development* The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts* Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans
Author | : Hans Jacob Hansen |
Publisher | : |
Total Pages | : 528 |
Release | : 1916 |
Genre | : Crustacea |
ISBN | : |
Download Crustacea Malacostraca Book in PDF, ePub and Kindle
Author | : Samia A. Temtamy |
Publisher | : Alan R. Liss |
Total Pages | : 596 |
Release | : 1978 |
Genre | : Medical |
ISBN | : |
Download The Genetics of Hand Malformations Book in PDF, ePub and Kindle