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Estrogen — Mystery Drug for the Brain?

Estrogen — Mystery Drug for the Brain?
Author: Christian Behl
Publisher: Springer Science & Business Media
Total Pages: 256
Release: 2011-06-28
Genre: Medical
ISBN: 3709161894

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It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.


Plasticity in the Adult Brain: From Genes to Neurotherapy

Plasticity in the Adult Brain: From Genes to Neurotherapy
Author: M.A. Hofman
Publisher: Elsevier
Total Pages: 496
Release: 2002-10-23
Genre: Science
ISBN: 008049773X

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In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.


Estrogen Effects in Psychiatric Disorders

Estrogen Effects in Psychiatric Disorders
Author: Niels Bergemann
Publisher: Springer Science & Business Media
Total Pages: 316
Release: 2005-01-24
Genre: Medical
ISBN: 9783211404850

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A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease. Recent research has focused on gender differences and there is increasing evidence that estrogens exert protective effects in schizophrenia. Hormonal fluctuations or lack of estrogen may increase the risk of depression among vulnerable women. Treatment of depression with estrogen may stabilize and restore disrupted homeostasis – as during post-partum, premenstrual, or perimenopausal conditions – and act as a psychomodulator to offset vulnerability to dysphoric mood when estrogen levels are significantly decreased, as in the case of postmenopausal women. Studies on the effect of estrogens on Alzheimer’s Disease are still rather controversial, they do, however, facilitate the hypothesis that estrogens may have a modifying effect on the onset and course of AD, at least in subgroups of patients.


Risk and Protective Factors in Schizophrenia

Risk and Protective Factors in Schizophrenia
Author: Heinz Häfner
Publisher: Springer Science & Business Media
Total Pages: 352
Release: 2012-12-06
Genre: Psychology
ISBN: 3642575161

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H. HAFNER Schizophrenia Research Unit, Central Institute of Mental Health, Mannheim, Germany The present volume contains the lectures and invited discussions of the sympo sium on "Risk and protective factors in schizophrenia - towards a conceptual model of the disease process", which was held at the International Science Forum of the University of Heidelberg from October 25 to 27, 200l. They are supple mented by a "Summary and outlook", in which Peter Jones gives a brief overview of the results and perspectives featured in the presentations and discussions. The contributions and discussions reflect the open-minded and creative atmosphere at the meeting. The systematically structured program of the symposium continued the tradition of the Search for the Causes of Schizophrenia symposia, which were th started in 1986 on the occasion of the 600 anniversary of the University of Hei delberg and which are co-organized with Prof. Wagner Farid Gattaz/Sao Paulo. The aim of these symposia and their proceedings volumes [6,8-10] has been to reflect the state of the art in schizophrenia research at their time, and they have successfully done so. In contrast, the present symposium pursued a more lim ited objective and was of a different type. It brought together, around a large table at the International Science Forum in Heidelberg, 22 invited speakers and dis cussants and an equal number of young scientists working in the research fields in question, who were thus given an opportunity to listen and to participate.


New Family Interventions and Associated Research in Psychiatric Disorders

New Family Interventions and Associated Research in Psychiatric Disorders
Author: Annette Schaub
Publisher: Springer Science & Business Media
Total Pages: 300
Release: 2012-12-06
Genre: Medical
ISBN: 3709161487

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This book is dedicated to the memory of Michael J. Goldstein, one of the pioneers in psychosocial intervention in psychiatry. The structure of this book follows Goldstein footsteps in this domain and is subdivided into family factors as well as intervention strategies for severe mental illness. Recent research on high expressed emotion (HEE) in schizophrenia (e.g., early psychosis) and borderline disorder, patients' perspectives of HEE as well as other variables predictive for relapse in recent-onset schizophrenia are covered in this book. Family treatment strategies in schizophrenia, depression, bipolar disorder, substance use disorders and illness management programs as well as pharmacological treatment strategies are illustrate and current studies presented.


Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology

Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology
Author: Mohammad Resa Nowrousian
Publisher: Springer Science & Business Media
Total Pages: 524
Release: 2012-12-06
Genre: Medical
ISBN: 3709176581

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Anemia is a frequent complication of cancer and its treatment. A number of clinical studies shows that the impact of anemia is much greater than previously thought. Beyond clinical symptoms, anemia significantly impairs physical and metabolic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. In this book, written by a group of outstanding international experts, the current knowledge on anemia in cancer and its treatment with rhEPO is presented. Future developments are also discussed. Based on a broad spectrum of topics, the book describes the scientific and clinical aspects of anemia in various fields of oncology and gives diagnostic and therapeutic recommendations on when and how to use rhEPO.


Molecular and Cellular Biology of Neuroprotection in the CNS

Molecular and Cellular Biology of Neuroprotection in the CNS
Author: Christian Alzheimer
Publisher: Springer Science & Business Media
Total Pages: 507
Release: 2012-12-06
Genre: Medical
ISBN: 1461501237

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Given the very limited capacity of regeneration in the brain, protecting neurons that are on the brink of death is a major challenge for basic and clinical neuroscience, with implications for a broad spectrum of acute and chronic neurological and psychiatric diseases. This book brings together leading experts from neurobiology, neurophysiology, neuropharmacology, neuroimmunology and clinical neuroscience to highlight the most recent milestones in this rapidly evolving field. The book will serve as a reference for both basic neuroscientists and clinicians interested in an authoritative update on the molecular and cellular biology of neuroprotection and its promises for new therapeutic strategies.


The Hormone Secret

The Hormone Secret
Author: Tami Meraglia
Publisher: Simon and Schuster
Total Pages: 288
Release: 2015-04-14
Genre: Health & Fitness
ISBN: 1476766509

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"Tami offers [a] ... thirty-day plan to restore healthy levels of testosterone and balance the relative levels of other hormones, based on lifestyle modifications such as supplements and nutritional adjustments. She also offers her Mediterranean Diet-based meal plan and low-impact exercise ideas that [may help] boost your energy"--Amazon.com.


The Female Brain

The Female Brain
Author: Louann Brizendine, MD
Publisher: Harmony
Total Pages: 306
Release: 2007-08-07
Genre: Science
ISBN: 0767928415

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Since Dr. Brizendine wrote The Female Brain ten years ago, the response has been overwhelming. This New York Times bestseller has been translated into more than thirty languages, has sold nearly a million copies between editions, and has most recently inspired a romantic comedy starring Whitney Cummings and Sofia Vergara. And its profound scientific understanding of the nature and experience of the female brain continues to guide women as they pass through life stages, to help men better understand the girls and women in their lives, and to illuminate the delicate emotional machinery of a love relationship. Why are women more verbal than men? Why do women remember details of fights that men can’t remember at all? Why do women tend to form deeper bonds with their female friends than men do with their male counterparts? These and other questions have stumped both sexes throughout the ages. Now, pioneering neuropsychiatrist Louann Brizendine, M.D., brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and who they love. While doing research as a medical student at Yale and then as a resident and faculty member at Harvard, Louann Brizendine discovered that almost all of the clinical data in existence on neurology, psychology, and neurobiology focused exclusively on males. In response to the overwhelming need for information on the female mind, Brizendine established the first clinic in the country to study and treat women’s brain function. In The Female Brain, Dr. Brizendine distills all her findings and the latest information from the scientific community in a highly accessible book that educates women about their unique brain/body/behavior. The result: women will come away from this book knowing that they have a lean, mean, communicating machine. Men will develop a serious case of brain envy.