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| Author | : Ajit Varki |
| Publisher | : CSHL Press |
| Total Pages | : 694 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9780879696818 |
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
| Author | : Ajit Varki |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2022 |
| Genre | : |
| ISBN | : 9781621824220 |
| Author | : Maureen E. Taylor |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 305 |
| Release | : 2011-04-21 |
| Genre | : Medical |
| ISBN | : 0199569118 |
Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.
| Author | : Thomas Lütteke |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2016-10-05 |
| Genre | : Science |
| ISBN | : 9781493941957 |
This book provides current glycoinformatics methods and protocols used to support the determination of carbohydrate structures in biological samples as well as carbohydrate structure databases, the interaction of carbohydrates with proteins, and theoretical and experimental methods to study their three-dimensional structure and dynamics. Glycoinformatics explores this recently emerged field, which has come into being in order to address the needs of encoding, storing, and analyzing carbohydrate ‘sequences’ and their taxonomy using computers. Written in the highly successful Methods in Molecular Biology series format, chapters contain the kind of detailed description and key implementation advice to ensure successful results. Authoritative and timely, Glycoinformatics demonstrates the progress that has been achieved in glycoinformatics, which indicates that it is no longer a niche subject covered by only a few scientists but is truly coming of age.
| Author | : Thisbe K. Lindhorst |
| Publisher | : John Wiley & Sons |
| Total Pages | : 333 |
| Release | : 2007-04-09 |
| Genre | : Science |
| ISBN | : 3527315284 |
Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.
| Author | : Elizabeth M. Shaw |
| Publisher | : CRC Press |
| Total Pages | : 558 |
| Release | : 2017-12-21 |
| Genre | : Architecture |
| ISBN | : 1482265702 |
Hydrology in Practice is an excellent and very successful introductory text for engineering hydrology students who go on to be practitioners in consultancies, the Environment Agency, and elsewhere. This fourth edition of Hydrology in Practice, while retaining all that is excellent about its predecessor, by Elizabeth M. Shaw, replaces the material on the Flood Studies Report with an equivalent section on the methods of the Flood Estimation Handbook and its revisions. Other completely revised sections on instrumentation and modelling reflect the many changes that have occurred over recent years. The updated text has taken advantage of the extensive practical experience of the staff of JBA Consulting who use the methods described on a day-to-day basis. Topical case studies further enhance the text and the way in which students at undergraduate and MSc level can relate to it. The fourth edition will also have a wider appeal outside the UK by including new material on hydrological processes, which also relate to courses in geography and environmental science departments. In this respect the book draws on the expertise of Keith J. Beven and Nick A. Chappell, who have extensive experience of field hydrological studies in a variety of different environments, and have taught undergraduate hydrology courses for many years. Second- and final-year undergraduate (and MSc) students of hydrology in engineering, environmental science, and geography departments across the globe, as well as professionals in environmental protection agencies and consultancies, will find this book invaluable. It is likely to be the course text for every undergraduate/MSc hydrology course in the UK and in many cases overseas too.
| Author | : Richard I. Morimoto |
| Publisher | : Perspectives Cshl |
| Total Pages | : 562 |
| Release | : 2019 |
| Genre | : Medical |
| ISBN | : 9781621822967 |
The entire life cycle of a protein-from synthesis and folding to transport and degradation-is carefully controlled by the proteostasis network. This network, consisting of many interconnected pathways and processes, manages protein homeostasis by dynamically responding to the needs of the cell. Stress and aging can challenge the proteostasis network, resulting in the aggregation of misfolded proteins-a feature of numerous neurodegenerative conditions. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on how the proteostasis network functions in healthy cells and the diseases that result when protein quality control goes awry. The contributors examine the relevant biochemical attributes of proteins (e.g., solubility), the functions of normal protein aggregates (e.g., biofilm formation in bacteria), and the various heat shock proteins, chaperones, translocation machineries, proteasomes, signaling factors, and transcriptional programs involved in proteostasis. The roles of specific subcellular structures-the endoplasmic reticulum, mitochondria, ribosomes, lysosomes, and cytoplasm-in protein quality control are covered, as is the regulation of proteostasis at the organismal level (e.g., via neuronal activity). Discussions of the responses by cells when errors in protein quality control occur, the medical disorders that can result (e.g., Alzheimer disease), and pharmacologic approaches to ameliorate protein conformational disorders are also included. This book is therefore an essential reference for biochemists, cell biologists, and all biomedical scientists wishing to understand the pathological consequences of and potential therapies for proteostasis deficiencies in common human diseases.
| Author | : Bastien D. Gomperts |
| Publisher | : Gulf Professional Publishing |
| Total Pages | : 444 |
| Release | : 2003-10-15 |
| Genre | : Medical |
| ISBN | : 9780122896323 |
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
| Author | : Olavo de O. Bittencourt Neto |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2020 |
| Genre | : Outer space |
| ISBN | : 9789462361218 |
This book is available digitally as an Open Access resource at www.boomdenhaag.nl. Click HERE to access the content. The development of space resources activities is happening now. In the absence of a clear framework to govern these activities there is a need to formulate such a framework in line with existing treaty obligations, in order to enable, support and coordinate the use of space resources in a manner that is acceptable for all stakeholders. This book provides a unique and comprehensive coverage of the work of The Hague International Space Resources Governance Group, established in 2016 with the purpose of assessing the need and laying the groundwork for such a framework. The Commentary contains the text, explanation, legal basis and alternatives discussed for each of the 20 Building Blocks that were adopted by the Working Group in 2019 and that could potentially form part of a future governance framework for space resource activities. The book is a useful reference tool for States, international organisations, industry, space agencies, scientists, academics and students in space law and policy interested in this new era of use and exploration of outer space.
| Author | : Rick Bond |
| Publisher | : |
| Total Pages | : 100 |
| Release | : 1988 |
| Genre | : Gardening |
| ISBN | : 9780897211512 |
