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Mechanisms of Environmental Mutagenesis-Carcinogenesis

Mechanisms of Environmental Mutagenesis-Carcinogenesis
Author: A. Kappas
Publisher: Springer Science & Business Media
Total Pages: 276
Release: 2012-12-06
Genre: Medical
ISBN: 1461538084

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The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.


Environmental Mutagenesis

Environmental Mutagenesis
Author: Environmental Mutagen Society. Meeting
Publisher:
Total Pages: 78
Release: 2003
Genre:
ISBN:

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Environmental Mutagenesis

Environmental Mutagenesis
Author: Consultant Surgeon Robin Phillips, Esq
Publisher: Academic Press
Total Pages: 0
Release: 1995-10
Genre:
ISBN: 9780122204326

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Germ-line and somatic mutations are recognized as significant causes of human disease, and so the detection, identification and study of mutagens in the environment is of increasing mutagenesis.Environmental Mutagenesis describes our current knowledge of the molecular mechanisms of mutagenesis and assesses the role of mutagens in cancer and inherited disease. Full details are also provided on all the major in vivo and in vitro methods of mutagenecity testing, including recently developed methods such as fluorescence in situ hybridization (FISH), the use of genetically engineered cells, and transgene technology.This book presents a unique overview of the current status of mutagenecity research and genetics toxicology in the form of reviews by leading researchers in the field. It is essential reading for all with an interest in genetic toxicology and molecular carcinogenesis, including molecular geneticists, genetic counselors and clinicians.


Program

Program
Author:
Publisher:
Total Pages: 83
Release: 1999
Genre:
ISBN:

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Molecular Biology of Mutagens and Carcinogens

Molecular Biology of Mutagens and Carcinogens
Author: Beatrice Singer
Publisher: Springer Science & Business Media
Total Pages: 352
Release: 2012-12-06
Genre: Medical
ISBN: 1461337720

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This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis. It seemed the appro priate time to sit back and summarize the results of several decades of research in laboratories in different countries. We are very grateful to the Rockefeller Foundation for inviting us to formulate and begin writing the book at the Center for International Studies in Bellagio, Italy, where we were Resident Scholars. We are fortunate to have had the assistance of so many colleagues around the world who cheerfully sent original data, figures, and preprints and lis tened patiently to us as we worked out the various conflicting ideas in this fast-moving. field. The names of these scientists are found within the tables, figures, and references. There is one person whose contributions we especially wish to acknowl edge. Professor Heinz Fraenkel-Conrat was present at the inception of this book and throughout the writing encouraged and criticized in apprOximately equal proportion. Finally, his editing and amalgamation of our two styles gave us great comfort. B.S. D.G.