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Emerging Technologies for Diagnosing Alzheimer's Disease

Emerging Technologies for Diagnosing Alzheimer's Disease
Author: Marianne Boenink
Publisher: Springer
Total Pages: 286
Release: 2016-09-13
Genre: Social Science
ISBN: 1137540974

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This book explores international biomedical research and development on the early diagnosis of Alzheimer's disease. It offers timely, multidisciplinary reflections on the social and ethical issues raised by promises of early diagnostics and asks under which conditions emerging diagnostic technologies can be considered a responsible innovation. The initial chapters in this edited volume provide an overview and a critical discussion of recent developments in biomedical research on Alzheimer's disease. Subsequent contributions explore the values at stake in current practices of dealing with Alzheimer's disease and dementia, both within and outside the biomedical domain. Novel diagnostic technologies for Alzheimer's disease emerge in a complex and shifting field, full of controversies. Innovating with care requires a precise mapping of how concepts, values and responsibilities are filled in through the confrontation of practices. In doing so, the volume offers a practice-based approach of responsible innovation that is also applicable to other fields of innovation.


Alzheimer's Disease

Alzheimer's Disease
Author: Harald Hampel
Publisher: Karger Medical and Scientific Publishers
Total Pages: 200
Release: 2012
Genre: Medical
ISBN: 3805598025

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How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the amyloid' or tau' hypotheses. This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.


Neurology in Clinical Practice

Neurology in Clinical Practice
Author: Walter George Bradley
Publisher:
Total Pages: 1672
Release: 2004
Genre: Medical
ISBN: 9780750674690

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New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.


Early Diagnosis of Alzheimer's Disease

Early Diagnosis of Alzheimer's Disease
Author: Leonard F. M. Scinto
Publisher: Springer Science & Business Media
Total Pages: 384
Release: 2000-02-09
Genre: Medical
ISBN:

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The three major approaches to diagnosis of AD -- radiological, biological, and neurophysiological -- are discussed in detail with chapters highlighting the most promising technologies within these approaches. The leading authors, all of whom are intimately involved with these emerging technologies, have developed this as an essential reference for neuropathologists, clinicians and researchers of Alzheimer's disease.


Alzheimer's Disease

Alzheimer's Disease
Author: Thimmaiah Govindaraju
Publisher: Royal Society of Chemistry
Total Pages: 695
Release: 2022-01-04
Genre: Medical
ISBN: 1839162740

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Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.


Reducing the Impact of Dementia in America

Reducing the Impact of Dementia in America
Author: National Academies of Sciences Engineering and Medicine
Publisher:
Total Pages:
Release: 2022-04-26
Genre:
ISBN: 9780309495035

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As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.


Bio-Inspired Algorithms and Devices for Treatment of Cognitive Diseases Using Future Technologies

Bio-Inspired Algorithms and Devices for Treatment of Cognitive Diseases Using Future Technologies
Author: Gupta, Shweta
Publisher: IGI Global
Total Pages: 309
Release: 2022-02-11
Genre: Technology & Engineering
ISBN: 179989536X

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As there are no proper medical tests available to predict certain diseases such as Alzheimer’s and Parkinson’s at an early stage, there is a need to further study and consider the potential uses of bio- and nature-inspired algorithms and future technologies such as machine learning in correlation to disease detection and treatment. Bio-Inspired Algorithms and Devices for Treatment of Cognitive Diseases Using Future Technologies considers new tools for early detection of cognitive brain diseases using devices and algorithms whose basic concept is taken from nature and discusses design, analysis, and application of various bionics or bio-inspired algorithms. Covering topics such as depression and cognitive science, this publication is an ideal resource for researchers, academicians, industry professionals, psychologists, psychiatrists, nurses, engineers, instructors, and students.


Alzheimer's Disease Drug Development

Alzheimer's Disease Drug Development
Author: Jeffrey Cummings
Publisher: Cambridge University Press
Total Pages: 575
Release: 2022-03-31
Genre: Business & Economics
ISBN: 1108838669

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Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.


Future Directions for the Demography of Aging

Future Directions for the Demography of Aging
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 409
Release: 2018-07-21
Genre: Social Science
ISBN: 0309474108

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Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.


Neurodegeneration and Alzheimer's Disease

Neurodegeneration and Alzheimer's Disease
Author: Ralph N. Martins
Publisher: John Wiley & Sons
Total Pages: 548
Release: 2019-07-10
Genre: Technology & Engineering
ISBN: 1119356784

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Understanding the impact of diet, exercise, genetics, and hormones on the risk and development of Alzheimer’s and other neurogenerative diseases Diet is widely known to impact on neurological function. Nevertheless, academic texts discussing this relationship are relatively few in number. This book therefore fills an important gap in the current literature. Opening with an overview of neurodegenerative diseases, particularly Alzheimer’s disease, the text then focuses on explaining the means by which glycemic control and lipid metabolism – and associated nutritional and lifestyle variables – may factor into such disorders’ prevention and treatment. An international group of experts in the fields of food science and neurodegeneration have contributed chapters that examine Alzheimer’s disease within a broad range of contexts. Offering dietary, genetic, and hormonal perspectives, the authors explore topics ranging from sugar consumption to digestive fermentation, and Alzheimer’s disease animal models to the cognition-enhancing effects of physical exercise. Also included are overviews of the latest research into current and developing methods of treatment and diagnosis, as well as differential diagnostics. This groundbreaking book: Explores how glucose metabolism, insulin resistance, lipid metabolism, and high intake of refined carbohydrates are linked to Alzheimer's disease Discusses how genetic makeup can impact risk of Alzheimer’s and Parkinson’s disease Examines cognitive changes in neurodegeneration, lists current tests for determining cognitive impairment, and provides information concerning differential diagnosis Discusses potential advantages of increasing antioxidant and micronutrient intake Reviews hormonal influences on neurodegeneration Examines the links between protein intake and Alzheimer’s disease. Neurodegeneration and Alzheimer's Disease is an essential resource for researchers, medical practitioners, dietitians, and students with an interest in neurological diseases and their diagnosis and risk factors, as well as diet-related conditions such as diabetes and obesity. Lifestyle and diet influence neurodegeneration risk, and a better understanding of this evidence amongst health professionals will hopefully lead to greater public awareness of how to reduce the likelihood of these widespread conditions.