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Electromagnetic Inverse Applications for Functional Brain Imaging

Electromagnetic Inverse Applications for Functional Brain Imaging
Author:
Publisher:
Total Pages: 4
Release: 1997
Genre:
ISBN:

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This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). This project addresses an important mathematical and computational problem in functional brain imaging, namely the electromagnetic {open_quotes}inverse problem.{close_quotes} Electromagnetic brain imaging techniques, magnetoencephalography (MEG) and electroencephalography (EEG), are based on measurements of electrical potentials and magnetic fields at hundreds of locations outside the human head. The inverse problem is the estimation of the locations, magnitudes, and time-sources of electrical currents in the brain from surface measurements. This project extends recent progress on the inverse problem by combining the use of anatomical constraints derived from magnetic resonance imaging (MRI) with Bayesian and other novel algorithmic approaches. The results suggest that we can achieve significant improvements in the accuracy and robustness of inverse solutions by these two approaches.


Magnetic Source Imaging of the Human Brain

Magnetic Source Imaging of the Human Brain
Author: Zhong-Lin Lu
Publisher: Taylor & Francis
Total Pages: 415
Release: 2003-10-17
Genre: Psychology
ISBN: 1135625689

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This book is designed to acquaint serious students, scientists, and clinicians with magnetic source imaging (MSI)--a brain imaging technique of proven importance that promises even more important advances. The technique permits spatial resolution of neural events on a scale measured in millimeters and temporal resolution measured in milliseconds. Although widely mentioned in literature dealing with cognitive neuroscience and functional brain imaging, there is no single book describing both the foundations and actual methods of magnetoencephalopgraphy and its underlying science, neuromagnetism. This volume fills a long-standing need, as it is accessible to scientists and students having no special background in the field, and makes it possible for them to understand this literature and undertake their own research. A self-contained unit, this book covers MSI from beginning to end, including its relationship to allied technologies, such as electroencephalography and modern functional imaging modalities. In addition, the book: *introduces the field to the non-specialist, providing a framework for the rest of the book; *provides a thorough review of the physiological basis of MSI; *describes the mathematical bases of MSI--the forward and inverse problems; *outlines new signal processing methods that extract information from single-trial MEG; *depicts the early, as well as the most recent versions of MSI technology; *compares MSI with other imaging methodologies; *describes new paradigms and analysis techniques in applying MSI to study human perception and cognition, which are also applicable to EEG; and *reviews some of the most important results in MSI from the most prominent researchers and laboratories around the world.


Adaptive Spatial Filters for Electromagnetic Brain Imaging

Adaptive Spatial Filters for Electromagnetic Brain Imaging
Author: Kensuke Sekihara
Publisher: Springer Science & Business Media
Total Pages: 247
Release: 2008-05-30
Genre: Technology & Engineering
ISBN: 3540793704

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Neural activity in the human brain generates coherent synaptic and intracellular currents in cortical columns that create electromagnetic signals which can be measured outside the head using magnetoencephalography (MEG) and electroencephalography (EEG). Electromagnetic brain imaging refers to techniques that reconstruct neural activity from MEG and EEG signals. Electromagnetic brain imaging is unique among functional imaging techniques for its ability to provide spatio-temporal brain activation profiles that reflect not only where the activity occurs in the brain but also when this activity occurs in relation to external and internal cognitive events, as well as to activity in other brain regions. Adaptive spatial filters are powerful algorithms for electromagnetic brain imaging that enable high-fidelity reconstruction of neuronal activity. This book describes the technical advances of adaptive spatial filters for electromagnetic brain imaging by integrating and synthesizing available information and describes various factors that affect its performance. The intended audience include graduate students and researchers interested in the methodological aspects of electromagnetic brain imaging.


Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy

Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy
Author: Lorenzo Crocco
Publisher: Springer
Total Pages: 250
Release: 2018-03-10
Genre: Technology & Engineering
ISBN: 3319750070

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This timely book presents innovative technologies for use in the diagnosis, monitoring, and treatment of brain disease. These technologies offer exciting possibilities in the medical field owing to their low-cost, portability and safety. The authors address cerebrovascular diseases such as stroke, ischemia, haemorrhage, and vasospasm, these diseases having an ever-increasing societal relevance due to the global ageing population. The authors describe the potential of novel techniques such as microwave imaging and present innovative modalities for treatment of brain tumours using electromagnetic fields and nano-composites, as well as for monitoring brain temperature during surgery. Finally, Emerging Electromagnetic Technologies for Brain Diseases Diagnostics, Monitoring and Therapy addresses the perspectives which arise from multi-modal multi-spectral EM modalities, which make a synergic use of the different portions of the electromagnetic spectrum. This text will be of interest to readers from various different areas, given the fundamental interdisciplinarity of the subject matter. This includes researchers or practitioners in the field of electrical engineering, applied physicists, and applied mathematicians working on imaging applications for biomedical and electromagnetic technologies. Neurologists and radiologists may also find this book of interest, as may graduate students in these areas.


Inverse Problems and Imaging

Inverse Problems and Imaging
Author: Luis L. Bonilla
Publisher: Springer
Total Pages: 207
Release: 2009-06-19
Genre: Mathematics
ISBN: 3540785477

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Nowadays we are facing numerous and important imaging problems: nondestructive testing of materials, monitoring of industrial processes, enhancement of oil production by efficient reservoir characterization, emerging developments in noninvasive imaging techniques for medical purposes - computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray and ultrasound tomography, etc. In the CIME Summer School on Imaging (Martina Franca, Italy 2002), leading experts in mathematical techniques and applications presented broad and useful introductions for non-experts and practitioners alike to many aspects of this exciting field. The volume contains part of the above lectures completed and updated by additional contributions on other related topics.


Simultaneous EEG and FMRI

Simultaneous EEG and FMRI
Author: Markus Ullsperger
Publisher: Oxford University Press
Total Pages: 332
Release: 2010-05-28
Genre: Medical
ISBN: 0195372735

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One of the major challenges in science is to study and understand the human brain. Numerous methods examining different aspects of brain functions have been developed and employed. To study systemic interactions brain networks in vivo, non-invasive methods such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have been used with great success. However, each of these methods can map only certain, quite selective aspects of brain function while missing others; and the inferences on neuronal processes and information flow are often rather indirect. To overcome these shortcomings of single methods, researchers have attempted to combine methods in order to make optimal use of their advantages while compensating their disadvantages. Hence, it is not surprising that soon after the introduction of fMRI as a neuroimaging method the possibilities of combinations with EEG have been explored.This book is intended to aid researchers who plan to set up a simultaneous EEG-fMRI laboratory and those who are interested in integrating electrophysiological and hemodynamic data. As will be obvious from the different chapters, this is a dynamically developing field in which several approaches are being tested, validated and compared. Currently, there is no one best solution for all problems available, but many promising techniques are emerging. This book shall give a comprehensive overview of these techniques. In addition, it points to open questions and directions for future research.


MEG

MEG
Author: Peter Hansen
Publisher: Oxford University Press
Total Pages: 449
Release: 2010-06-21
Genre: Medical
ISBN: 0195307232

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Magnetoencephalography (MEG) is an exciting brain imaging technology that allows real-time tracking of neural activity, making it an invaluable tool for advancing our understanding of brain function. In this comprehensive introduction to MEG, Peter Hansen, Morten Kringelbach, and Riitta Salmelin have brought together the leading researchers to provide the basic tools for planning and executing MEG experiments, as well as analyzing and interpreting the resulting data. Chapters on the basics describe the fundamentals of MEG and its instrumentation, and provide guidelines for designing experiments and performing successful measurements. Chapters on data analysis present it in detail, from general concepts and assumptions to analysis of evoked responses and oscillatory background activity. Chapters on solutions propose potential solutions to the inverse problem using techniques such as minimum norm estimates, spatial filters and beamformers. Chapters on combinations elucidate how MEG can be used to complement other neuroimaging techniques. Chapters on applications provide practical examples of how to use MEG to study sensory processing and cognitive tasks, and how MEG can be used in a clinical setting. These chapters form a complete basic reference source for those interested in exploring or already using MEG that will hopefully inspire them to try to develop new, exciting approaches to designing and analyzing their own studies. This book will be a valuable resource for researchers from diverse fields, including neuroimaging, cognitive neuroscience, medical imaging, computer modelling, as well as for clinical practitioners.


Functional Brain Imaging

Functional Brain Imaging
Author: Gert Pfurtscheller
Publisher: Hogrefe & Huber Publishing
Total Pages: 284
Release: 1988
Genre: Medical
ISBN:

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This is a unique and richly illustrated book that concisely explains topographic mapping of electrical and magnetic brain activity, and relates this technique to metabolic and regional blood flow studies. Also addressed are important results of experimental and clinical investigations, as well as problems of electrical magnetic data and topographic display.