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Advances in Cancer Research

Advances in Cancer Research
Author:
Publisher: Elsevier
Total Pages: 285
Release: 2000-04-19
Genre: Medical
ISBN: 9780080490229

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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented. New Paradigms for the Treatment of Cancer: The Role of Anti-aiogenesis Agents The Hepatocyte Growth Factor/Met Pathway in Development, Tumorigenesis, and B-Cell Differentiation Clinical Targets for Anti-metastasis Therapy Animal Models of Melanoma: Recent Advances and Future Prospects The Indispensable Role of Microenvironment in the Natural History of Low-Grade B-Cell Neoplasms Epstein-Barr Virus Latency: LMP2, a Regulator or Means for Epstein-Barr Birus Biochemistry and Pathological Importance of Mucin-Associated Antigens in Gastrointenstinal Neoplasia Studies on Polyomavirus Persistence and Polyomavirus-Induced Tumor Development in Relation to the Immune System


Brain Metastases

Brain Metastases
Author: Jeffrey Raizer
Publisher: Springer Science & Business Media
Total Pages: 240
Release: 2007-10-03
Genre: Medical
ISBN: 0387692215

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Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.


Journal of Cell Science

Journal of Cell Science
Author:
Publisher:
Total Pages: 690
Release: 1999
Genre: Cytology
ISBN:

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Withrow and MacEwen's Small Animal Clinical Oncology

Withrow and MacEwen's Small Animal Clinical Oncology
Author: Stephen J. Withrow
Publisher: Elsevier Health Sciences
Total Pages: 863
Release: 2007-01-01
Genre: Medical
ISBN: 0721605583

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Focusing on cancer in dogs and cats, this extensively updated 4th edition provides comprehensive coverage of the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. Ideal for students, practitioners, and those involved in academic research, this book's full-color images and user-friendly format provide quick and easy access to today's most important information on cancer in the small animal patient. Full-color format throughout and full-color illustrations make information more accessible and provide accurate representations of clinical appearance.Chapters are clustered into four major sections: The Biology and Pathogenesis of Cancer, Diagnostic Procedures for the Cancer Patient, Therapeutic Modalities for the Cancer Patient, and Specific Malignancies in the Small Animal Patient.The consistent format includes incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies in the small animal cancer patient.Features cutting edge information on the complications of cancer, pain management, and the latest treatment modalities. The latest information on the etiology of cancer, including genetic, chemical, physical, and hormonal factors, as well as cancer-causing viruses.Coverage of molecular-targeted therapy of cancer, plus new and emerging therapeutic techniques.New information on molecular diagnostic procedures for the cancer patient.The latest diagnostic imaging techniques in clinical oncology.Discussions of compassion and supportive care, from chronic pain management and nutrition to end-of-life issues and grief support.


Angiogenesis Assays

Angiogenesis Assays
Author: Carolyn A. Staton
Publisher: John Wiley & Sons
Total Pages: 410
Release: 2007-01-11
Genre: Medical
ISBN: 047002934X

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Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.


Experimental Metastasis: Modeling and Analysis

Experimental Metastasis: Modeling and Analysis
Author: Anastasia Malek
Publisher: Springer Science & Business Media
Total Pages: 212
Release: 2013-12-02
Genre: Medical
ISBN: 940077835X

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Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic cancer dissemination and metastases development. The book is structured in according with various metastatic pathways reflecting molecular specificity of metastatic process as well as anatomical specificity of aria of dissemination. Each chapter is introduced by short discussion of clinical aspects of certain metastatic pathway. Especial attention is paid for methods of visualization, quantification and analysis of the modeled metastases. Additional chapter is devoted to methods of mathematic modeling of tumor spread. The data presented in the book may be helpful for cancer researchers and oncologists.


Withrow and MacEwen's Small Animal Clinical Oncology - E-Book

Withrow and MacEwen's Small Animal Clinical Oncology - E-Book
Author: David M. Vail
Publisher: Elsevier Health Sciences
Total Pages: 865
Release: 2019-07-23
Genre: Medical
ISBN: 0323594972

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NEW! Expert co-authors and contributors bring a valuable perspective with research experience. NEW! Thoroughly UPDATED content includes important updates on recently approved and in-development veterinary cancer drugs, and critical advances in radiation delivery.


Therapeutic targeting of circulating tumor cells

Therapeutic targeting of circulating tumor cells
Author: Michael R. King
Publisher: Frontiers E-books
Total Pages: 134
Release:
Genre:
ISBN: 2889190897

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There has been increased interest in circulating tumor cells (CTC), as a diagnostic readout of disease progression, and a tool for personalized medicine. The next generation of therapy for metastatic cancer may well involve neutralizing CTC as a means to prevent metastasis. In this topic we focus on recent research exploring this concept.