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| Author | : André H. Erhardt |
| Publisher | : Frontiers Media SA |
| Total Pages | : 209 |
| Release | : 2023-02-15 |
| Genre | : Science |
| ISBN | : 2832514588 |
| Author | : Gabriella Bretti |
| Publisher | : Springer Nature |
| Total Pages | : 261 |
| Release | : 2023-09-17 |
| Genre | : Mathematics |
| ISBN | : 3031357159 |
Mathematical modelling and computer simulations are playing a crucial role in the solution of the complex problems arising in the field of biomedical sciences and provide a support to clinical and experimental practices in an interdisciplinary framework. Indeed, the development of mathematical models and efficient numerical simulation tools is of key importance when dealing with such applications. Moreover, since the parameters in biomedical models have peculiar scientific interpretations and their values are often unknown, accurate estimation techniques need to be developed for parameter identification against the measured data of observed phenomena. In the light of the new challenges brought by the biomedical applications, computational mathematics paves the way for the validation of the mathematical models and the investigation of control problems. The volume hosts high-quality selected contributions containing original research results as well as comprehensive papers and survey articles including prospective discussion focusing on some topical biomedical problems. It is addressed, but not limited to: research institutes, academia, and pharmaceutical industries.
| Author | : Jan Awrejcewicz |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 336 |
| Release | : 2008-12-26 |
| Genre | : Technology & Engineering |
| ISBN | : 1402087780 |
This volume contains the invited papers presented at the 9th International Conference "Dynamical Systems — Theory and Applications" held in Lódz, Poland, December 17-20, 2007, dealing with nonlinear dynamical systems. The conference brought together a large group of outstanding scientists and engineers, who deal with various problems of dynamics encountered both in engineering and in daily life. Topics covered include, among others, bifurcations and chaos in mechanical systems; control in dynamical systems; asymptotic methods in nonlinear dynamics; stability of dynamical systems; lumped and continuous systems vibrations; original numerical methods of vibration analysis; and man-machine interactions. Thus, the reader is given an overview of the most recent developments of dynamical systems and can follow the newest trends in this field of science. This book will be of interest to to pure and applied scientists working in the field of nonlinear dynamics.
| Author | : W.E. Schiesser |
| Publisher | : CRC Press |
| Total Pages | : 235 |
| Release | : 2019-11-25 |
| Genre | : Medical |
| ISBN | : 1000763730 |
Time delayed (lagged) variables are an inherent feature of biological/physiological systems. For example, infection from a disease may at first be asymptomatic, and only after a delay is the infection apparent so that treatment can begin. Thus, to adequately describe physiological systems, time delays are frequently required and must be included in the equations of mathematical models. The intent of this book is to present a methodology for the formulation and computer implementation of mathematical models based on time delay ordinary differential equations (DODEs) and partial differential equations (DPDEs). The DODE/DPDE methodology is presented through a series of example applications, particularly in biomedical science and engineering (BMSE). The computer-based implementation of the example models is explained with routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, for example, no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The DPDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The example applications can first be executed to confirm the reported solutions, then extended by variation of the parameters and the equation terms, and even the formulation and use of alternative DODE/DPDE models.
| Author | : Stefanie Winkelmann |
| Publisher | : Springer Nature |
| Total Pages | : 284 |
| Release | : 2021-01-04 |
| Genre | : Mathematics |
| ISBN | : 3030623874 |
The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems.
| Author | : Victor A. Sadovnichiy |
| Publisher | : Springer |
| Total Pages | : 477 |
| Release | : 2016-08-16 |
| Genre | : Technology & Engineering |
| ISBN | : 3319406736 |
Focused on recent advances, this book covers theoretical foundations as well as various applications. It presents modern mathematical modeling approaches to the qualitative and numerical analysis of solutions for complex engineering problems in physics, mechanics, biochemistry, geophysics, biology and climatology. Contributions by an international team of respected authors bridge the gap between abstract mathematical approaches, such as applied methods of modern analysis, algebra, fundamental and computational mechanics, nonautonomous and stochastic dynamical systems on the one hand, and practical applications in nonlinear mechanics, optimization, decision making theory and control theory on the other. As such, the book will be of interest to mathematicians and engineers working at the interface of these fields.
| Author | : Y. Cherruault |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 273 |
| Release | : 2012-12-06 |
| Genre | : Mathematics |
| ISBN | : 9400954921 |
Approach your problems from the right It isn't that they can't see the solution. It end and begin with the answers. Then is that they can't see the problem. one day, perhaps you will find the final question. G.K. Chesterton. The Scandal of Father Brown 'The point of a Pin'. 'The Hermit Clad in Crane Feathers' in R. van Gulik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, cod ing theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical pro gramming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electrical engineering can use Stein spaces.
| Author | : Trachette Jackson |
| Publisher | : Springer |
| Total Pages | : 240 |
| Release | : 2015-07-06 |
| Genre | : Mathematics |
| ISBN | : 1493927825 |
This volume highlights problems from a range of biological and medical applications that can be interpreted as questions about system behavior or control. Topics include drug resistance in cancer and malaria, biological fluid dynamics, auto-regulation in the kidney, anti-coagulation therapy, evolutionary diversification and photo-transduction. Mathematical techniques used to describe and investigate these biological and medical problems include ordinary, partial and stochastic differentiation equations, hybrid discrete-continuous approaches, as well as 2 and 3D numerical simulation.
| Author | : Brian P. Ingalls |
| Publisher | : MIT Press |
| Total Pages | : 423 |
| Release | : 2022-06-07 |
| Genre | : Science |
| ISBN | : 0262545829 |
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
| Author | : Peter Benner |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 465 |
| Release | : 2020-12-07 |
| Genre | : Mathematics |
| ISBN | : 3110497751 |
An increasing complexity of models used to predict real-world systems leads to the need for algorithms to replace complex models with far simpler ones, while preserving the accuracy of the predictions. This three-volume handbook covers methods as well as applications. This third volume focuses on applications in engineering, biomedical engineering, computational physics and computer science.
