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Dynamic Energy and Mass Budgets in Biological Systems

Dynamic Energy and Mass Budgets in Biological Systems
Author: S. A. L. M. Kooijman
Publisher: Cambridge University Press
Total Pages: 448
Release: 2000-03-23
Genre: Nature
ISBN: 9780521786089

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The Dynamic Energy Budget theory unifies the commonalties between organisms, as prescribed by the implications of energetics, and links different levels of biological organisation (cells, organisms and populations). The theory presents simple mechanistic rules that describe the uptake and use of energy and nutrients and the consequences for physiological organization throughout an organism's life cycle. All living organisms are covered in a single quantitative framework, the predictions of which are tested against a variety of experimental results at a range of levels of organisation. The theory explains many general observations, such as the body size scaling relationships of certain physiological traits, and provides a theoretical underpinning to the method of indirect calorimetry. In each case, the theory is developed in elementary mathematical terms, but a more detailed discussion of the methodological aspects of mathematical modelling is also included.


Dynamic Energy Budgets in Biological Systems

Dynamic Energy Budgets in Biological Systems
Author: S. A. L. M. Kooijman
Publisher: Cambridge University Press
Total Pages: 364
Release: 1993-11-04
Genre: Nature
ISBN: 9780521452236

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Dynamic Energy Budget Theory for Metabolic Organisation

Dynamic Energy Budget Theory for Metabolic Organisation
Author: S. A. L. M. Kooijman
Publisher: Cambridge University Press
Total Pages: 533
Release: 2010
Genre: Mathematics
ISBN: 052113191X

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The Dynamic Energy Budget theory unifies the commonalities between organisms and links different levels of biological organisation.


A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment

A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment
Author: Natàlia Garcia-Reyero
Publisher: Springer
Total Pages: 422
Release: 2018-02-24
Genre: Science
ISBN: 3319660845

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Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based vision for human and ecological health assessment relying on in vitro systems and predictive models, The Adverse Outcome Pathway framework provides a simplified and structured way to organize toxicological information. Within the book, a systems biology approach supplies the tools to infer, link, and quantify the molecular initiating events and the key events and key event relationships leading to adverse outcomes. The advancement of these tools is crucial for the successful implementation of AOPs for regulatory purposes.


Individual-based Modeling and Ecology

Individual-based Modeling and Ecology
Author: Volker Grimm
Publisher: Princeton University Press
Total Pages: 445
Release: 2013-11-28
Genre: Science
ISBN: 1400850622

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Individual-based models are an exciting and widely used new tool for ecology. These computational models allow scientists to explore the mechanisms through which population and ecosystem ecology arises from how individuals interact with each other and their environment. This book provides the first in-depth treatment of individual-based modeling and its use to develop theoretical understanding of how ecological systems work, an approach the authors call "individual-based ecology.? Grimm and Railsback start with a general primer on modeling: how to design models that are as simple as possible while still allowing specific problems to be solved, and how to move efficiently through a cycle of pattern-oriented model design, implementation, and analysis. Next, they address the problems of theory and conceptual framework for individual-based ecology: What is "theory"? That is, how do we develop reusable models of how system dynamics arise from characteristics of individuals? What conceptual framework do we use when the classical differential equation framework no longer applies? An extensive review illustrates the ecological problems that have been addressed with individual-based models. The authors then identify how the mechanics of building and using individual-based models differ from those of traditional science, and provide guidance on formulating, programming, and analyzing models. This book will be helpful to ecologists interested in modeling, and to other scientists interested in agent-based modeling.


Demography in Ecotoxicology

Demography in Ecotoxicology
Author: Jan Kammenga
Publisher: John Wiley & Sons
Total Pages: 323
Release: 2000-12-19
Genre: Science
ISBN: 0471490024

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Demography in Ecotoxicology focuses on the interface between toxicology, life history and demographic theory. This comprehensive book examines the different ways of adequately assessing the potential impact of toxic stress on populations and discusses how to obtain an insight into the underlying physiological and genetic mechanisms. The theory is illustrated with empiricial observations on a number of species and organisational levels and the book incorporates: * case studies; * real data; * life history models; * methodologies; and, * recommendations for risk assessment Written by an international team of researchers, Demography in Ecotoxicology will be invaluable to ecotoxicologists, ecologists and wildlife conservationists in academia, industry and regulatory bodies wishing to gain a greater understanding into the prediction and effects of natural and man-made toxicants on populations.


Cell Biology by the Numbers

Cell Biology by the Numbers
Author: Ron Milo
Publisher: Garland Science
Total Pages: 400
Release: 2015-12-07
Genre: Science
ISBN: 1317230698

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A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid


Thermodynamics and Ecological Modelling

Thermodynamics and Ecological Modelling
Author: Sven E. Jorgensen
Publisher: CRC Press
Total Pages: 384
Release: 2018-10-03
Genre: Technology & Engineering
ISBN: 1482278618

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Thermodynamics is used increasingly in ecology to understand the system properties of ecosystems because it is a basic science that describes energy transformation from a holistic view. In the last decade, many contributions to ecosystem theory based on thermodynamics have been published, therefore an important step toward integrating these theories and encouraging a more wide spread use of them is to present them in one volume. An ecosystem consists of interdependent living organisms that are also interdependent with their environment, all of which are involved in a constant transfer of energy and mass within a general state of equilibrium or dis-equilibrium. Thermodynamics can quantify exactly how "organized" or "disorganized" a system is - an extremely useful to know when trying to understand how a dynamic ecosystem is behaving. A part of the Environmental and Ecological (Math) Modeling series, Thermodynamics and Ecology is a book-length study - the first of its kind - of the current thinking on how an ecosystem can be explained and predicted in terms of its thermodynamical behavior. After the introductory chapters on the fundamentals of thermodynamics, the book explains how thermodynamic theory can be specifically applied to the "measurement" of an ecosystem, including the assessment of its state of entropy and enthalpy. Additionally, it will show economists how to put these theories to use when trying to quantify the movement of goods and services through another type of complex living system - a human society.