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Author | : David Kritchevsky |
Publisher | : Springer Science & Business Media |
Total Pages | : 433 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1468409670 |
Download Drugs, Lipid Metabolism, and Atherosclerosis Book in PDF, ePub and Kindle
This volume comprises the proceedings of the sixth International Symposium on Drugs Affecting Lipid Meta bolism. Since the first of these symposia in 1960 these triennial meetings have been devoted to the exploration of new ideas, new data and new concepts related to lipid metabolism and atherosclerosis. The sixth Meeting was particularly stimulating in this regard. The concept of the "protective" action of HDL was thoroughly explored within the framework of its molecular biology with data on its epidemiological as well as its in vitro mechan ism(s) of action being discussed. The action of drugs on arterial and HDL metabolism was also discussed as were newer aspects of platelet aggregation, especially as related to prostaglandins. New ground was also broken in discussions of lipid mobilization and mechan isms of hypocholesteremia. We are indebted to the many organizations who con tributed generously to the support of this meeting. Among the sponsors, the assistance of the Lorenzini Foundation was especially helpful. As in all meetings of this type, the hard work of the local organizing committee was instrumental in its success. We are grateful to Mrs. Caroline Hyatt and Mr. Ralph Hollerorth for their invaluable help in the secretariat. We are also deeply indebted to Miss Jane T. Kolimaga for her expert assistance in the preparation of this volume. David Kritchevsky Rodolfo Paoletti William L. Holmes vii Contents LIPOPROTEINS AND DRUGS Lipoprotein Metabolism - New Insights from Cell Biology. . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 D. Steinberg Lipoprotein Metabolism in Man. . . . . . . . . . . . . . . . . . . .
Author | : David Kritchevsky |
Publisher | : Springer |
Total Pages | : 456 |
Release | : 2014-01-15 |
Genre | : |
ISBN | : 9781468409680 |
Download Drugs, Lipid Metabolism, and Atherosclerosis Book in PDF, ePub and Kindle
Author | : Alberico L. Catapano |
Publisher | : Springer Science & Business Media |
Total Pages | : 510 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401117039 |
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A great deal of experimental, clinical and epidemiological data have been gathered to confirm the strict and causal correlation between plasma lipoproteins and coronary heart disease. However, as usually happens in research, many more interesting issues are being studied, opening new fields of research for the future. These new advances, together with the combined efforts of cell biologists and lipoprotein chemists, have set the pace for an exciting period of research and clinical applications of diets and drugs affecting plasma and cell lipids. This volume, which includes the work of many of the leading world labortories, represents an authoritative and up-to-date appraisal of the status of the art and a stimulus to future research at the laboratory and clinical level in a fascinating area of clinical and preventive medicine.
Author | : David Kritchevsky |
Publisher | : Springer Science & Business Media |
Total Pages | : 503 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1461324599 |
Download Drugs Affecting Lipid Metabolism VIII Book in PDF, ePub and Kindle
The Proceedings of the Eight International Symposium on Drugs Affecting Lipid Metabolism (8th D.A.L.M.) is the subject of this volume. Since the first symposium in 1960, each successive meeting has broken new ground in the field of pharmacological control of lipid levels - offering new and stimulating insights and exposing the audience to the state of the art. The field has progressed sufficiently to permit discussion of the cellular biology of athero sclerosis. The opening session was devoted to pathology, macrophages, lipoproteins and their receptors and choles terol ester metabolism. Because of the recent emergence of new apolipoprotein technology, a workshop devoted sole ly to apolipoprotein methodology was introduced followed by a plenary session devoted to their metabolism and structure. Another rapidly developing area of atherosclerosis research is non-invasive assessment of this condition. Accordingly, a session was devoted to new techniques for this research modality. The final plenary sessions were devoted to the roles of drugs and diet in athero~ scl~rosis - cause, treatment and mechanisms of action. The meeting was summarized by Dr. O.J. Pollak, one of the "founding fathers" of this field. There were nine sessions of proffered papers whose abstracts appear in this volume. In addition, special workshops (to be reported elsewhere) were devoted to several drugs including Oiyzanol, Probucol and Etofibrate.
Author | : David Kritchevsky |
Publisher | : |
Total Pages | : 520 |
Release | : 1965 |
Genre | : Drugs |
ISBN | : |
Download Drugs Affecting Lipid Metabolism Book in PDF, ePub and Kindle
Author | : Silvio Garattini |
Publisher | : |
Total Pages | : 620 |
Release | : 1961 |
Genre | : Drugs |
ISBN | : |
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Author | : David Kritchevsky |
Publisher | : |
Total Pages | : 540 |
Release | : 1967 |
Genre | : Drugs |
ISBN | : |
Download Drugs Affecting Lipid Metabolism: Cholesterol and atherosclerosis. Plasma triglycerides and lipoproteins. Drugs affecting plasma lipids Book in PDF, ePub and Kindle
Author | : D. Kritchevsky |
Publisher | : |
Total Pages | : |
Release | : 1967 |
Genre | : |
ISBN | : |
Download Drugs Affecting Lipid Metabolism. Pt. 1. Cholesterol and Atherosclerosis, Plasma Triglycerides and Lipoproteins, Drugs Affecting Plasma Lipids Book in PDF, ePub and Kindle
Author | : Milan Symposium on Drugs Affecting Lipid Metabolism |
Publisher | : |
Total Pages | : 624 |
Release | : 1961 |
Genre | : |
ISBN | : |
Download Drugs affecting lipid metabolism, proceedings Book in PDF, ePub and Kindle
Author | : Antonio M. Gotto Jr. |
Publisher | : Springer |
Total Pages | : 710 |
Release | : 2011-10-14 |
Genre | : Medical |
ISBN | : 9789401066259 |
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Even a brief scan of the table of contents of the present volume is enough to disclose the diversity of research interests and opinions in the field of lipidology. It is precisely this diversity that is the strength of our field and that was showcased by the XII International Symposium of DRUGS AFFECTING LIPID METABOLISM (DALM). The papers published here from these proceedings may be divided into three categories: those that define-and refine---our understanding ofthe clinical benefit of aggressive lipid management, those that develop our knowledge of ris!. assessment, and those that discuss the genetic, bio~hemical, and biophysical mechanisms underlying the pathology of coronary heart disease. On the clinical front, further analysis of the results of the Scandinavian Simvastatin Survival Study (4S) has indicated the cost-effectiveness of therapy in patients with established coronary heart disease. The West of Scotland Coronary Prevention Study (WOSCOPS), whose methodology was described at the DALM XII symposium, has demonstrated in a mostly primary-prevention population what 4S demonstrated for secondary prevention the year before: aggressive lipid-regulating therapy reduces coronary heart disease morbidity and mortality rates without concurrently increasing mortality from noncardiovascular causes. In the future, important considerations will be to develop protocols that maximize benefit in groups underrepresented in traditional clinical research for example, women and the elderly-and to improve compliance to existing treatment regimens. Furthermore, antioxidant, omega-3 fatty acid, and gene therapies warrant further investigation.