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Drugs and the Future

Drugs and the Future
Author: David J. Nutt
Publisher: Elsevier
Total Pages: 616
Release: 2006-12-11
Genre: Psychology
ISBN: 9780080467740

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Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA


Love is the Drug

Love is the Drug
Author: Brian D. Earp
Publisher: Manchester University Press
Total Pages: 313
Release: 2020-01-30
Genre: Science
ISBN: 1526145561

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What if there were a pill for love? Or an anti-love drug, designed to help us break up? This controversial and timely new book argues that recent medical advances have brought chemical control of our romantic lives well within our grasp. Substances affecting love and relationships, whether prescribed by doctors or even illicitly administered, are not some far-off speculation – indeed our most intimate connections are already being influenced by pills we take for other purposes, such as antidepressants. Treatments involving certain psychoactive substances, including MDMA—the active ingredient in Ecstasy—might soon exist to encourage feelings of love and help ordinary couples work through relationship difficulties. Others may ease a breakup or soothe feelings of rejection. Such substances could have transformative implications for how we think about and experience love. This brilliant intervention into the debate builds a case for conducting further research into "love drugs" and "anti-love drugs" and explores their ethical implications for individuals and society. Rich in anecdotal evidence and case-studies, the book offers a highly readable insight into a cutting-edge field of medical research that could have profound effects on us all. Will relationships be the same in the future? Will we still marry? It may be up to you to decide whether you want a chemical romance.


Drugs and Thugs

Drugs and Thugs
Author: Russell Crandall
Publisher: Yale University Press
Total Pages: 521
Release: 2020-10-27
Genre: Political Science
ISBN: 030025587X

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A sweeping and highly readable work on the evolution of America’s domestic and global drug war How can the United States chart a path forward in the war on drugs? In Drugs and Thugs, Russell Crandall uncovers the full history of this war that has lasted more than a century. As a scholar and a high-level national security advisor to both the George W. Bush and Obama administrations, he provides an essential view of the economic, political, and human impacts of U.S. drug policies. Backed by extensive research, lucid and unbiased analysis of policy, and his own personal experiences, Crandall takes readers from Afghanistan to Colombia, to Peru and Mexico, to Miami International Airport and the border crossing between El Paso and Juarez to trace the complex social networks that make up the drug trade and drug consumption. Through historically driven stories, Crandall reveals how the war on drugs has evolved to address mass incarceration, the opioid epidemic, the legalization and medical use of marijuana, and America’s shifting foreign policy.


The Future of Drug Safety

The Future of Drug Safety
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 346
Release: 2007-02-27
Genre: Medical
ISBN: 0309133947

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In the wake of publicity and congressional attention to drug safety issues, the Food and Drug Administration (FDA) requested the Institute of Medicine assess the drug safety system. The committee reported that a lack of clear regulatory authority, chronic underfunding, organizational problems, and a scarcity of post-approval data about drugs' risks and benefits have hampered the FDA's ability to evaluate and address the safety of prescription drugs after they have reached the market. Noting that resources and therefore efforts to monitor medications' riskâ€"benefit profiles taper off after approval, The Future of Drug Safety offers a broad set of recommendations to ensure that consideration of safety extends from before product approval through the entire time the product is marketed and used.


Ethnopharmacology of Medicinal Plants

Ethnopharmacology of Medicinal Plants
Author: Christophe Wiart
Publisher: Springer Science & Business Media
Total Pages: 236
Release: 2007-11-04
Genre: Medical
ISBN: 1597451606

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In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs. One could have reasonably expected the discovery of an arsenal of drugs from the millions of plant extracts randomly tested, but “hits” can be inactive in vitro or too toxic, some molecules need to be metabolized first to be active, and false-positive and false-negative results are common. The bitter truth is that the robotic approach in discovering drugs from plants has proven, to date, its inability to excavate the hundreds of molecules that will contribute to the health progress of Man. However, one can reasonably see that the last patches of primary rainforest on earth hold still hundreds of spectacularly active drugs that await discovery.


Out of Nature

Out of Nature
Author: Kara Rogers
Publisher: University of Arizona Press
Total Pages: 216
Release: 2012-11-01
Genre: Science
ISBN: 0816599580

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About half of all species under threat of extinction in the world today are plants. The loss of plant biodiversity is disturbing for many reasons, but especially because it is a reflection of the growing disconnect between humans and nature. Plants have been used for millennia in traditional systems of healing and have held a significant place in drug development for Western medicine as well. Despite the recent dominance of synthetic drug production, natural product discovery remains the backbone of drug development. As the diversity of life on Earth is depleted and increasing numbers of species become lost to extinction, we continue to lose opportunities to achieve advances in medicine. Through stories of drug revelation in nature and forays into botany, human behavior, and conservation, Kara Rogers sheds light on the multiple ways in which humans, medicine, and plants are interconnected. With accessible and engaging writing, she explores the relationships between humans and plants, relating the stories of plant hunters of centuries past and examining the impact of human activities on the environment and the world's biodiversity. Rogers also highlights the role that plant-based products can play in encouraging conservation and protecting the heritage and knowledge of indigenous peoples. Out of Nature provides a fresh perspective on modern drug innovation and its relationship with nature. The book delves into the complexity of biophilia—the innate human attraction to life in the natural world—and suggests that the reawakening of this drive is fundamental to expanding conservation efforts and improving medicine. Rogers's examination of plants, humans, and drug discovery also conveys a passionate optimism for the future of biodiversity and medicine. Including a collection of hand-drawn maps and plant illustrations created by the author, this well-researched narrative will inspire as well as inform.


Undoing Drugs

Undoing Drugs
Author: Maia Szalavitz
Publisher: Hachette GO
Total Pages: 304
Release: 2021-05-11
Genre:
ISBN: 9780738285764

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Journalist and author of the New York Times bestselling Unbroken Brain tackles the revolutionary concept of harm reduction, how it can transform the treatment of addiction, and how it holds the potential to revolutionize our treatment of behavioral and societal issues. In her New York Times bestseller Unbroken Brain, journalist Maia Szalavitz took an unflinching look at addiction, challenging the idea of the "broken brain" to offer a groundbreaking perspective on addiction as a learning disorder. Now she turns her keen eye and narrative powers to the surprisingly simple--and extremely divisive--practice of harm reduction, which is a revolutionary means to solving the drug addiction crisis. Drug overdoses now kill more Americans annually than guns, cars or breast cancer. But in the name of "sending the right message," we have criminalized drug addiction, denied those who are addicted medical care, housing and other benefits, and have deliberately allowed the spread of fatal diseases. Yet there is an alternative to our present system, one that has been proven to work, but which runs counter to the received wisdom of our criminal and medical industrial complexes. It is called harm reduction. A surprisingly simple idea with enormous power, harm reduction takes the focus off of drug use and instead works to minimize associated damage. It represents the philosophy behind needle exchange programs and providing heroin addicts with the overdose medication naloxone instead of arresting them. It is focused not on punishing pleasure but on minimizing harm; in essence, it is a wholesale refutation of the American way of justice. Undoing Drugs tells the story of harm reduction. It will show how this concept has begun to transform the treatment of addiction and how it holds the potential to revolutionize how we deal with a range of other urgent behavioral and societal issues. Harm reduction challenges people to prioritize radical empathy and kindness over punishment as a way of not only dealing with drug use, but also in questions related to racism, sexism, disability and inequality. And, as Szalavitz shows, it says unequivocally that we must be more concerned about saving lives and health than about criminalizing quality-of-life crimes. Szalavitz argues for a practical application of the Hippocratic oath to "First, do no harm" beyond medicine and to those who urgently need it most.


Facing Addiction in America

Facing Addiction in America
Author: Office of the Surgeon General
Publisher: Createspace Independent Publishing Platform
Total Pages: 420
Release: 2017-08-15
Genre:
ISBN: 9781974580620

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All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.


Medications for Opioid Use Disorder Save Lives

Medications for Opioid Use Disorder Save Lives
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 175
Release: 2019-06-16
Genre: Medical
ISBN: 0309486483

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The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.


Drugs for Life

Drugs for Life
Author: Joseph Dumit
Publisher: Duke University Press
Total Pages: 277
Release: 2012-09-03
Genre: Business & Economics
ISBN: 0822348713

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Challenges our understanding of health, risks, facts, and clinical trials [Payot]