Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions PDF Download
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| Author | : Manjunath P. Pai |
| Publisher | : Springer |
| Total Pages | : 336 |
| Release | : 2018-03-05 |
| Genre | : Medical |
| ISBN | : 3319724223 |
Download Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions Book in PDF, ePub and Kindle
The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.
| Author | : Manjunath P. Pai |
| Publisher | : Springer |
| Total Pages | : 576 |
| Release | : 2018-03-19 |
| Genre | : Medical |
| ISBN | : 3319724169 |
Download Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions Book in PDF, ePub and Kindle
The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.
| Author | : Stephen C. Piscitelli |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 534 |
| Release | : 2007-10-28 |
| Genre | : Medical |
| ISBN | : 1592599249 |
Download Drug Interactions in Infectious Diseases Book in PDF, ePub and Kindle
Over the past 25 years, the world’s population has witnessed an explosion in kno- edge about infectious diseases. The global population is coming to the realization that diseases long recognized to cause substantial suffering, such as malaria, tuberculosis, schistosomiasis, and hepatitis, can be diagnosed and treated, and that transmission can be prevented using tools that are available, and which may be becoming increasingly affordable. The global population is recognizing that few infections are local: the travel of humans, other animals, insects, and food transport pathogens around the world, often with astonishing rapidity. New pathogens are appearing, either newly recognized or newly developing, such as severe acute respiratory syndrome (SARS), avian inf- enza, metapneumovirus, or hepatitis C, which are causing human morbidity and m- tality. Finally, there is growing fear that dangerous pathogens may be intentionally introduced into human populations by deranged individuals or terrorist organizations. The potential to use drugs or biologic agents to treat and prevent infectious diseases has increased dramatically over the past quarter century as we have learned more about the biology of many of these agents, and as we have developed techniques to discover new agents by high throughput screening programs and by sophisticated drug design and synthesis.
| Author | : Ivan H. Stockley |
| Publisher | : |
| Total Pages | : 1018 |
| Release | : 1996 |
| Genre | : Medical |
| ISBN | : |
Download Drug Interactions Book in PDF, ePub and Kindle
This is a source book of adverse drug reactions covering their clinical importance, mechanisms and management. This fourth edition has been revised from an extensive database. Major interaction mechanisms are followed by alphabetically-arranged material covering all the drug groups. As with prior editions, there is a series of monographs with a consistent plan devised to offer quick and easy reading. Both British and American drug names have been used throughout the book and bibliogrpahies are provided for those who wish to use the book as a reference source.
| Author | : Stephen C. Piscitelli |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 698 |
| Release | : 2011-09-08 |
| Genre | : Medical |
| ISBN | : 1617792136 |
Download Drug Interactions in Infectious Diseases Book in PDF, ePub and Kindle
The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe cocktail studies has been included to highlight an important research tool for drug development. These chapters address material that cannot be retrieved easily in the medical literature. The highly acclaimed food-drug interactions as well as the study design and analysis chapters remain definitive references. The newly written drug-cytokine interaction highlights the need for our improved understanding of the complex interrelationship of acute infection, inflammation, and the risk of drug interactions. Informative tables on specific drug-drug interactions are provided throughout the chapters as a quick clinical resource. The Third Edition of Drug Interactions in Infectious Diseases is a distillation of relevant drug interactions associated with antimicrobials, infection, and inflammation. This concise review of the mechanisms and strategies to manage drug interactions should be valuable to all health care practitioners. Features • Definitive reference source of up-to-date information on antimicrobial drug interactions • Informative tables on the degree of interaction for specific antimicrobial agents • In-depth discussion of mechanisms and potential mechanistic pathways of interaction • New chapters on non-HIV antiviral, antimalarial, antiparasitic, and macrolide, azalide and ketolide agents • New chapter on probe-cocktail studies as a research tool to study drug-drug interactions • Inclusion of new antimicrobial agents and their associated drug interactions • First rate chapters on study design and analysis, and drug-food interactions • A fresh perspective on drug-cytokine interactions • Authoritative chapter on regulatory considerations of drug interactions during drug development
| Author | : Honghui Zhou |
| Publisher | : John Wiley & Sons |
| Total Pages | : 272 |
| Release | : 2013-05-10 |
| Genre | : Medical |
| ISBN | : 1118630211 |
Download Drug-Drug Interactions for Therapeutic Biologics Book in PDF, ePub and Kindle
Strategize, plan, and execute comprehensive drug-drug interaction assessments for therapeutic biologics Offering both theory and practical guidance, this book fully explores drug-drug interaction assessments for therapeutic biologics during the drug development process. It draws together and analyzes all the latest findings and practices in order to present our current understanding of the topic and point the way to new research. Case studies and examples, coupled with expert advice, enable readers to better understand the complex mechanisms of biologic drug-drug interactions. Drug-Drug Interactions for Therapeutic Biologics features contributions from leading international experts in all areas of therapeutic biologics drug development and drug-drug interactions. The authors' contributions reflect a thorough review and analysis of the literature as well as their own firsthand laboratory experience. Coverage includes such essential topics as: Drug-drug interaction risks in combination with small molecules and other biologics Pharmacokinetic and pharmacodynamic drug-drug interactions In vitro methods for drug-drug interaction assessment and prediction Risk-based strategies for evaluating biologic drug-drug interactions Strategies to minimize drug-drug interaction risk and mitigate toxic interactions Key regulations governing drug-drug interaction assessments for therapeutic biologics. Drug-Drug Interactions for Therapeutic Biologics is recommended for pharmaceutical and biotechnology scientists, clinical pharmacologists, medicinal chemists, and toxicologists. By enabling these readers to understand how therapeutic biologics may interact with other drugs, the book will help them develop safer, more effective therapeutic biologics.
| Author | : Ashraf Mozayani |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 662 |
| Release | : 2003-10-15 |
| Genre | : Medical |
| ISBN | : 1592596541 |
Download Handbook of Drug Interactions Book in PDF, ePub and Kindle
A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.
| Author | : Ivan H. Stockley |
| Publisher | : |
| Total Pages | : 82 |
| Release | : 1977 |
| Genre | : Drug interactions |
| ISBN | : 9780853691198 |
Download Drug Interactions and Their Mechanisms Book in PDF, ePub and Kindle
| Author | : Frederic J. Zucchero |
| Publisher | : American Pharmaceutical Association |
| Total Pages | : 468 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9780917330933 |
Download Pocket Guide to Evaluations of Drug Interactions Book in PDF, ePub and Kindle
A condensed version of Evaluations of Drug Interactions, designed to facilitate quick access to the information most frequently needed by busy health practitioners. It contains 952 drug interaction monographs organized by drug class. Most monographs contain eight concise pieces of information and the volume is indexed by generic names.
| Author | : Karen Baxter |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2006 |
| Genre | : Arzneimittelwechselwirkung |
| ISBN | : 9780853696247 |
Download Stockley's Drug Interactions Book in PDF, ePub and Kindle
First published over twenty years ago, Stockley's Drug Interactions is still the most indispensable and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed yet concise monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management. Individual interactions are assembled alphabetically into chapters, grouped therapeutically, pharmacologically or individually. Both Recommended International Nonproprietary Names (rlNN) and US Adopted Names (USAN) are used throughout the book
