Drug Development For Cancer And Diabetes PDF Download
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Author | : K. Saravanan |
Publisher | : CRC Press |
Total Pages | : 393 |
Release | : 2020-08-30 |
Genre | : Medical |
ISBN | : 1000639983 |
Download Drug Development for Cancer and Diabetes Book in PDF, ePub and Kindle
Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency
Author | : Anne Le |
Publisher | : Springer |
Total Pages | : 186 |
Release | : 2018-06-26 |
Genre | : Medical |
ISBN | : 331977736X |
Download The Heterogeneity of Cancer Metabolism Book in PDF, ePub and Kindle
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author | : Derek LeRoith |
Publisher | : Springer Science & Business Media |
Total Pages | : 290 |
Release | : 2011-09-18 |
Genre | : Medical |
ISBN | : 146140598X |
Download Insulin-like Growth Factors and Cancer Book in PDF, ePub and Kindle
The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Author | : Michael R. Bleavins |
Publisher | : John Wiley & Sons |
Total Pages | : 559 |
Release | : 2011-09-20 |
Genre | : Medical |
ISBN | : 1118210425 |
Download Biomarkers in Drug Development Book in PDF, ePub and Kindle
Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound selection, reduce late-stage attrition, and open the door to personalized medicine. Biomarkers in Drug Development is divided into eight parts: Part One offers an overview of biomarkers and their role in drug development. Part Two highlights important technologies to help researchers identify new biomarkers. Part Three examines the characterization and validation process for both drugs and diagnostics, and provides practical advice on appropriate statistical methods to ensure that biomarkers fulfill their intended purpose. Parts Four through Six examine the application of biomarkers in discovery, preclinical safety assessment, clinical trials, and translational medicine. Part Seven focuses on lessons learned and the practical aspects of implementing biomarkers in drug development programs. Part Eight explores future trends and issues, including data integration, personalized medicine, and ethical concerns. Each of the thirty-eight chapters was contributed by one or more leading experts, including scientists from biotechnology and pharmaceutical firms, academia, and the U.S. Food and Drug Administration. Their contributions offer pharmaceutical and clinical researchers the most up-to-date understanding of the strategies used for and applications of biomarkers in drug development.
Author | : Bruce H. Littman |
Publisher | : Cambridge University Press |
Total Pages | : 385 |
Release | : 2011-01-31 |
Genre | : Medical |
ISBN | : 113949872X |
Download Translational Medicine and Drug Discovery Book in PDF, ePub and Kindle
This book focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. It is essential for anyone interested in translational medicine from a variety of backgrounds: university institutes, medical schools, pharmaceutical companies and drug development researchers and decision-makers.
Author | : Asfar Azmi |
Publisher | : Academic Press |
Total Pages | : 0 |
Release | : 2019-04-17 |
Genre | : Business & Economics |
ISBN | : 9780128147047 |
Download Animal Models in Cancer Drug Discovery Book in PDF, ePub and Kindle
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.
Author | : C. Davis |
Publisher | : Springer |
Total Pages | : 442 |
Release | : 2013-11-08 |
Genre | : Medical |
ISBN | : 1137349476 |
Download Unhealthy Pharmaceutical Regulation Book in PDF, ePub and Kindle
This is the first book to examine how effectively American and supranational EU governments have regulated innovative pharmaceuticals during the last 30 years regarding public health. It explains why pharmaceutical regulation has been misdirected by commercial interests and misconceived ideologies.
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 103 |
Release | : 2020-01-27 |
Genre | : Medical |
ISBN | : 0309498511 |
Download The Role of NIH in Drug Development Innovation and Its Impact on Patient Access Book in PDF, ePub and Kindle
To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.
Author | : Trisha Dunning |
Publisher | : John Wiley & Sons |
Total Pages | : 616 |
Release | : 2020-01-23 |
Genre | : Medical |
ISBN | : 111952086X |
Download Care of People with Diabetes Book in PDF, ePub and Kindle
Now in its fifth edition, Care of People with Diabetes is a comprehensive clinical manual for nurses, healthcare professionals and students alike, providing an extensive summary of the most up-to-date knowledge in a rapidly developing field, as well as the role of education and self-care in achieving desirable outcomes. Covering both the theory and evidence-based practice of diabetes care, this authoritative volume integrates traditional thinking and innovative concepts to challenge readers to ‘think outside the box’ when rendering care. New and updated content on the pathophysiology of diabetes and the implications for management, how to apply guideline recommendations in practice, and contemporary evidence for best practice diabetes care Highlights personalised care and shared, evidence-based decision-making, emphasising the need for effective communication to reduce judgmental language and the negative effect it has on wellbeing and outcomes Written by internationally recognised experts in diabetes care, research and education Includes a range of learning features, such as practice questions, key learning points, diagrams, and further reading suggestions Care of People with Diabetesis an essential companion to clinical practice for both trainee and experienced nurses and healthcare professionals, particularly those in acute care settings, and students undertaking diabetes courses or preparing for qualification exams.
Author | : Qing Yan |
Publisher | : Springer Nature |
Total Pages | : 618 |
Release | : 2022-09-06 |
Genre | : Medical |
ISBN | : 107162573X |
Download Pharmacogenomics in Drug Discovery and Development Book in PDF, ePub and Kindle
This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful Methods in Molecular Biology series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care. Authoritative and up-to-date, Pharmacogenomics in Drug Discovery and Development, Third Edition aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.