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Drug Delivery for the Retina and Posterior Segment Disease

Drug Delivery for the Retina and Posterior Segment Disease
Author: Jayvadan K. Patel
Publisher: Springer
Total Pages: 494
Release: 2018-10-08
Genre: Medical
ISBN: 3319958070

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This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.


Ocular Drug Delivery: Advances, Challenges and Applications

Ocular Drug Delivery: Advances, Challenges and Applications
Author: Richard T. Addo
Publisher: Springer
Total Pages: 190
Release: 2016-11-16
Genre: Medical
ISBN: 3319476912

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The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.


Treatise on Ocular Drug Delivery

Treatise on Ocular Drug Delivery
Author: Ashim K. Mitra
Publisher: Bentham Science Publishers
Total Pages: 301
Release: 2013-06-26
Genre: Medical
ISBN: 1608051757

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A multidisciplinary approach is increasingly being adapted by the Pharmaceutical industry to tackle several challenges in developing efficacious treatment solutions. The field of Ophthalmology is no less different. Treatise on Ocular Drug Delivery is a unique collection of information put together by various experts in the field. One of the major goals behind this volume is to link clinical information with the current strategies employed in ocular drug delivery. This monograph covers a range of topics on ocular pharmacology. Chapters in the e-book cover several aspects of drug delivery research such as the biochemical background of specific eye diseases, challenges for ocular drug delivery, the role of influx and efflux transporters, novel drug delivery systems, pharmacokinetics, regulatory aspects, and patenting opportunities for researchers. This E-Book would serve as a suitable reference for pharmacy graduates, medical students, professional scientists and ophthalmic clinicians in academic and industrial laboratories.


Ocular Drug Delivery Systems

Ocular Drug Delivery Systems
Author: Deepak Thassu
Publisher: CRC Press
Total Pages: 461
Release: 2012-10-02
Genre: Medical
ISBN: 1439848017

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Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Ba


Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems
Author: Ashim K. Mitra
Publisher: CRC Press
Total Pages: 847
Release: 2019-12-02
Genre:
ISBN: 9780367446765

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The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.


Biomaterials and Regenerative Medicine in Ophthalmology

Biomaterials and Regenerative Medicine in Ophthalmology
Author: Traian Chirila
Publisher: Elsevier
Total Pages: 565
Release: 2009-12-18
Genre: Technology & Engineering
ISBN: 184569743X

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With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration


Intraocular Drug Delivery

Intraocular Drug Delivery
Author: Glenn J. Jaffe
Publisher: CRC Press
Total Pages: 385
Release: 2006-03-13
Genre: Medical
ISBN: 1420016504

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This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-r


Essential Pharmacokinetics

Essential Pharmacokinetics
Author: Thorsteinn Loftsson
Publisher: Academic Press
Total Pages: 179
Release: 2015-03-25
Genre: Medical
ISBN: 0128014911

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Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes Illustrates how to write and evaluate drug registration files