Developmental Biology of the Mammary Gland
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Total Pages | : |
Release | : 1999 |
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Total Pages | : |
Release | : 1999 |
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Author | : John A. Mol |
Publisher | : Springer Science & Business Media |
Total Pages | : 309 |
Release | : 2006-04-11 |
Genre | : Science |
ISBN | : 0306468328 |
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author | : Adriana P. Visbal |
Publisher | : |
Total Pages | : 266 |
Release | : 2011 |
Genre | : |
ISBN | : |
Author | : Finian Martin |
Publisher | : Methods in Molecular Biology |
Total Pages | : 372 |
Release | : 2018-11-12 |
Genre | : Medical |
ISBN | : 9781493982127 |
Author | : Edmund B. Rucker |
Publisher | : |
Total Pages | : 0 |
Release | : 2014 |
Genre | : Breast |
ISBN | : 9781629488530 |
This book is a compilation of manuscripts that encompass a breadth of information from different species including rodents, dogs, cows, goats, and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology. Therefore, this book presents in depth analyses of these diseases over several chapters and different model systems. Rodent and canine cancer models are discussed, which are very relevant in understanding the roles that genes and the environment play in human breast cancer. In the livestock industry, mastitis in the dairy sector has a deep economic impact globally, and results in over a billion dollar loss annually. Several chapters are devoted towards this disease in dairy cattle, sheep and goats, with an underlying theme of generating newer detection strategies to detect infections at an earlier stage. An up-to-date description of the most important signaling pathways and mechanisms that impact both development and disease are included. A gamut of sub-disciplines are found throughout the book that covers the main aspects of anatomy, physiology, cell biology, genetics, and molecular biology in both development and diseases of the mammary gland.
Author | : Marc Bracke |
Publisher | : |
Total Pages | : 231 |
Release | : 2011 |
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Author | : Zuzana Koledova |
Publisher | : Frontiers Media SA |
Total Pages | : 158 |
Release | : 2020-10-27 |
Genre | : Science |
ISBN | : 288966094X |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author | : Mina Bissell |
Publisher | : Cold Spring Harbor Perspective |
Total Pages | : 0 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 9780879699062 |
Studies of mammary gland biology are critically important given the prevalence of breast cancer in the population. There are many other reasons to study this organ, however. It represents an excellent model system for research into developmental mechanisms, gene regulation, tissue organization, hormonal action, secretion, and stem cell biology, revealing general principles that can be extended to other organs and tissues. This book provides valuable lessons for all cell, developmental, and cancer biologists.
Author | : Margaret C. Neville |
Publisher | : Springer |
Total Pages | : 656 |
Release | : 1987-11-30 |
Genre | : Medical |
ISBN | : |
Author | : E. Anderson |
Publisher | : Springer Science & Business Media |
Total Pages | : 519 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461309433 |
The idea for this book arose during the 1985 Gordon Conference on "Mammary Gland Biology". New developments in the methodology of cell biology and the explosive growth of molecular biology had begun to impact upon our understanding of mammary gland growth and function. It seemed a propitious time for summarizing the current status of knowledge of the cell and molecular biology of mammary cancer and for attempting to outline future areas of concern and interest. The reviews presented here were completed by the Fall of 1986. Although new insights will surely continue to emerge, it is hoped that the material in this volume will form not only a current update but a basic core of information for future experiments. We have not attempted to cover all areas of mammary gland transformation. Those areas where recent detailed reviews are already available have been omitted. Also, the areas of normal gland development, cell ultrastructure, hormone responsiveness, chemotherapy and clinical aspects of mammary cancer have not been included. Instead, we have selected those areas where the development of new methodology, reagents and results have led to new ideas about mammary gland function and development as they are related to neoplasia.