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Development of Genetic Resistance to Infection

Development of Genetic Resistance to Infection
Author: David P. Clark
Publisher:
Total Pages: 9
Release: 2010
Genre: Civilization
ISBN: 9780132102520

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"This Element is an excerpt from Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today (ISBN: 9780137019960) by David P. Clark. When a virulent epidemic rages, some humans survive and some die. Before vaccination, antibiotics, and modern medical technology, what decided who was fortunate and who was not? In addition to sheer luck, both social and biological factors affect the chances of catching a disease, as well as the likelihood of surviving"--Resource description page.


Development of Genetic Resistance to Infection

Development of Genetic Resistance to Infection
Author: David Clark
Publisher: Pearson Education
Total Pages: 21
Release: 2010-04-16
Genre: Education
ISBN: 0132102242

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This is the eBook version of the printed book. This Element is an excerpt from Germs, Genes, & Civilization: How Epidemics Shaped Who We Are Today (9780137019960) by David P. Clark. Available in print and digital formats. ¿ Why do some survive disease while others die--and how does humanity develop greater genetic resistance to infection? ¿ When a virulent epidemic rages, some humans survive and some die. Before vaccination, antibiotics, and modern medical technology, what decided who was fortunate and who was not? In addition to sheer luck, both social and biological factors affect the chances of catching a disease, as well as the likelihood of surviving. Let’s start with strictly biological factors....


Immunodeficient Rodents

Immunodeficient Rodents
Author: Institute of Laboratory Animal Resour
Publisher: Legare Street Press
Total Pages: 0
Release: 2023-07-18
Genre:
ISBN: 9781019453094

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This informative guide provides a comprehensive overview of the biology and care of immunodeficient rodents, which are essential for the study of human diseases and the development of new treatments. It is an invaluable resource for scientists, veterinarians, and animal care professionals. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases
Author: Michel Tibayrenc
Publisher: Elsevier
Total Pages: 773
Release: 2010-12-17
Genre: Medical
ISBN: 0123848903

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Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field


Immunology and Evolution of Infectious Disease

Immunology and Evolution of Infectious Disease
Author: Steven A. Frank
Publisher: Princeton University Press
Total Pages: 364
Release: 2002-07-21
Genre: Medical
ISBN: 9780691095950

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Genetic Control of Natural Resistance to Infection and Malignancy

Genetic Control of Natural Resistance to Infection and Malignancy
Author: Emil Skamene
Publisher: Elsevier
Total Pages: 621
Release: 2012-12-02
Genre: Medical
ISBN: 032314439X

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Genetic Control of Natural Resistance to Infection and Malignancy is a collection of papers presented at the 1980 Proceedings of an International Symposium of the Canadian Society for Immunology held in Montreal, Quebec. It provides information about the different models of genetic resistance to various diseases. The book offers an overview of the genetic determination of the susceptibility or resistance to infection and malignancy. It also discusses the importance of genetic resistance not only in the first-line observation of infections and tumors, but also in chemotherapy and immunotherapy. It then explains the genetic control of resistance to parasitic, bacterial, and virus infections, as well as to tumor growth. It further discusses the genetic control of macrophage differentiation and function.


Gene Therapy for Viral Infections

Gene Therapy for Viral Infections
Author: Patrick Arbuthnot
Publisher: Academic Press
Total Pages: 391
Release: 2015-06-01
Genre: Science
ISBN: 0124114520

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Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field


Genetic Susceptibility to Infectious Diseases

Genetic Susceptibility to Infectious Diseases
Author: Richard A. Kaslow M.D.
Publisher: Oxford University Press
Total Pages: 464
Release: 2008-03-03
Genre: Medical
ISBN: 019972122X

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Infectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. No currently plubished text on either genetics or infectious diseases focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1. No other work on the selected genes regulating immunity deals as systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. And no other book gives as meaningful a picture of how these genes operate in infectious disease as Section 3 will.