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| Author | : Apeng Chen |
| Publisher | : |
| Total Pages | : 260 |
| Release | : 2017 |
| Genre | : Liquid chromatography |
| ISBN | : |
| Author | : Per Erlandsson |
| Publisher | : Linköping University Electronic Press |
| Total Pages | : 59 |
| Release | : 2018-03-20 |
| Genre | : |
| ISBN | : 9176853357 |
Electrokinetic phenomena, motion caused by an applied electric field, can be used to separate molecules based on charge as in capillary electrophoresis, or pump liquids with electroosmosis. As microfluidic devices are becoming more advanced, involving multiple stages (sequential reactions) and requiring smaller amounts of reagent, the demand for precise fluid control and integrated electrodes increases. One of the main reasons for developing lab-on-a-chip devices is the realization of decentralized diagnostics, allowing patients to be monitored without going to a hospital or diagnosed in situations where healthcare infrastructure is not available. The first paper of this thesis investigates the differences in characteristics between an electroosmotic pump with metal electrodes and one using electrochemically active polymer electrodes. With metal electrodes reactions normally take place at the metal/electrolyte interface where the electrolyte or species therein are either reduced or oxidized to maintain an electric current. For water-based electrolytes the electrolysis of water produces pH altering species and gas, which can interfere with microfluidic systems. As electrochemically active electrodes can themselves be reduced or oxidized, the amount of undesired reactions at the polymer/electrolyte interface can be significantly decreased. The second and third papers investigate the use of porous potassium monoliths as electroosmotic pumps in microfluidic devices using electrochemically active electrodes. Porous potassium silicate monoliths were created inside fused silica capillaries in order to increase the pumps resistance to pressure driven flow. Potassium silicate structures without a fused silica capillary as a scaffold were produced in molds of polydimethylsiloxane. Asymmetric pumping properties of these stand-alone monolith was sometimes observed. Monoliths were produced in conical molds in an attempt to increase the asymmetric behavior.
| Author | : Anurag Rathore |
| Publisher | : CRC Press |
| Total Pages | : 504 |
| Release | : 2003-09-16 |
| Genre | : Science |
| ISBN | : 9780203912980 |
Electrokinetic Phenomena emphasizes the impact of methods such as capillary zone electrophoresis, capillary electrochromatography, and capillary gel electrophoresis on the analysis of biomolecules. This reference reveals the electrokinetic phenomena that underlie high-performance electro-based analytical tools and vividly depicts how electro
| Author | : Abbas Afkhami |
| Publisher | : Elsevier |
| Total Pages | : 391 |
| Release | : 2023-05-10 |
| Genre | : Science |
| ISBN | : 0323972373 |
Analytical Nanochemistry provides readers with a comprehensive review of the application of nanomaterial in analytical chemistry. It explains the fundamental concepts involved in utilizing nanomaterials including their classification, synthesis, functionalization, characterization methods, separation, and isolation techniques, as well as toxicity. It also covers fundamental information on different aspects of analytical procedures and method development. Furthermore, it emphasizes micro- and nano-enabled analytical devices and instruments as well as nanotools for nanoanalysis. The book opens with a section on fundamentals (Section 1), then continues with a section on the role of nanomaterials in analytical procedures (Section 2), including sample preparation, separation, and detection. The third section (Section 3) includes chapters on micro- and nano-enabled devices, as most miniaturized microsystems include nanofeatures. The book concludes with a fourth section (Section 4) on future perspectives, covering nanoanalysis, bioanalysis, toxic risks, and limitations of both technology and commercialization. This book serves as a valuable resource for students, instructors, and researchers in analytical chemistry, nanomaterials, and nanotechnology investigating the use of nanotechnology in their analytical procedures. Covers the synthesis methods, functionalization process, and characterization methods of nanomaterials Uses numerous visual elements to illustrate key points, including flowcharts, process diagrams, photographs, and visual schemes Presents fundamental concepts and updated hot topics such as miniaturization in analytical chemistry, nanotools for nano-analysis, micro total analysis systems, and lab-on-a-chip
| Author | : Dr. Kunal Pal |
| Publisher | : Woodhead Publishing |
| Total Pages | : 1006 |
| Release | : 2019-06-15 |
| Genre | : Technology & Engineering |
| ISBN | : 0081024215 |
Bioelectronics and Medical Devices: From Materials to Devices-Fabrication, Applications and Reliability reviews the latest research on electronic devices used in the healthcare sector, from materials, to applications, including biosensors, rehabilitation devices, drug delivery devices, and devices based on wireless technology. This information is presented from the unique interdisciplinary perspective of the editors and contributors, all with materials science, biomedical engineering, physics, and chemistry backgrounds. Each applicable chapter includes a discussion of these devices, from materials and fabrication, to reliability and technology applications. Case studies, future research directions and recommendations for additional readings are also included. The book addresses hot topics, such as the latest, state-of the-art biosensing devices that have the ability for early detection of life-threatening diseases, such as tuberculosis, HIV and cancer. It covers rehabilitation devices and advancements, such as the devices that could be utilized by advanced-stage ALS patients to improve their interactions with the environment. In addition, electronic controlled delivery systems are reviewed, including those that are based on artificial intelligences. Presents the latest topics, including MEMS-based fabrication of biomedical sensors, Internet of Things, certification of medical and drug delivery devices, and electrical safety considerations Presents the interdisciplinary perspective of materials scientists, biomedical engineers, physicists and chemists on biomedical electronic devices Features systematic coverage in each chapter, including recent advancements in the field, case studies, future research directions, and recommendations for additional readings
| Author | : Séverine Le Gac |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 333 |
| Release | : 2009 |
| Genre | : Science |
| ISBN | : 085404129X |
Focussing on mass spectrometry, this book illustrates how microfluidics and lab-on-a-chip devices satisfy the need for miniaturized, enhanced chemical analysis.
| Author | : Nazmul Islam |
| Publisher | : |
| Total Pages | : 121 |
| Release | : 2007 |
| Genre | : |
| ISBN | : |
AC electrokinetics is the study of particle and fluid motion induced by AC electric fields. In the last decade it has received increasing interest due to its important applications in micro total analysis systems and miniaturized biomedical devices. With the application of very low voltage (~1V[subscript rms]), AC electrokinetics can be utilized to control and manipulate particles and fluids at the micro/nano scale, which are very difficult to achieve with existing techniques, such as pressure driven flow. Through the interaction of ac electric fields and particles/fluids, ac electrokinetics can be used to sort, separate and filter particles, and to pump and mix fluids. AC electrokinetics can operate at relatively low voltages, which is suitable for integrated lab-on-a-chip systems. This research investigates AC electroosmosis for manipulating nanofluids/ particles with an aim to provide a generic platform for the transport and concentration functions in microfluidic devices. It is envisioned that these concepts can be integrated with life science and biomedical technologies to develop a new generation of labs-on-a-chip, with high-efficiency particle manipulation and sensing, micropumps and microfluidic mixers. Two topics are studied in this thesis. One is the trapping/concentration of colloidal and bio-particles. Particle trapping is conducted adjacent to an electrolyte/electrode interface of the gold (Au) electrode pair. We have developed the capability to integrate AC electroosmotic trap and micro-cantilever (MC) in a microfluidic system. By combining both experimental investigation and theoretical analysis, this research work demonstrates a microcantilever particle trap. The second topic is the transport/mixing of fluids. An original biased AC electroosmotic pump is being developed, and experiments have been performed to prove the concept. Both numerical simulation and pumping experiment is done to optimize the pumping efficiency. The control of the biased AC-EO pumping is also suggested by using the feedback loop. The thesis concludes with suggestions on how the concepts can be exploited for the development of new strategies for colloidal separation, manipulation for microfluidics and bioMEMS technologies.
| Author | : Aaron Ray Wheeler |
| Publisher | : |
| Total Pages | : 286 |
| Release | : 2003 |
| Genre | : |
| ISBN | : |
| Author | : Thomas Laurell |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 644 |
| Release | : 2004 |
| Genre | : Microchemistry |
| ISBN | : 9780854048960 |
| Author | : Damien W. M. Arrigan |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 412 |
| Release | : 2016 |
| Genre | : Science |
| ISBN | : 1849738319 |
Electrochemical methods of chemical analysis have been widely used for many years, the purpose of this volume is to address research and development advances based on new and re-vitalised methods, new materials with enhanced properties and new devices that achieve better electroanalytical signal generation.
