Determining Discriminating Concentrations Of Insecticides For Monitoring Resistance In Mosquitoes PDF Download

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Determining discriminating concentrations of insecticides for monitoring resistance in mosquitoes

Determining discriminating concentrations of insecticides for monitoring resistance in mosquitoes
Author:
Publisher: World Health Organization
Total Pages: 109
Release: 2021-05-21
Genre: Medical
ISBN: 9240045201

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The document provides an up-to-date recommendations made to WHO by the experts of WHO consultations on discriminating concentrations of insecticides for monitoring resistance in adult mosquito vectors. It is an outcome of a WHO multi-centre study (2017–2021) performed by 23 laboratories in different regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations for monitoring resistance in Anopheles and Aedes spp. The document describes a new WHO bottle bioassay method for testing susceptibility of mosquitoes to insecticides that are not suitable for impregnation on filter papers and makes recommendations for future scientific research on development of methods and procedures for testing resistance against insecticides with new, novel or distinct modes of action. Making use of the recommendations made to WHO by the experts, WHO will soon update current WHO test methods and procedures and publish standard operating procedures for testing insecticide resistance in mosquitoes, which in turn will be useful to the national vector-borne disease control programmes, in particular the entomological surveillance units, and the research community for monitoring insecticide resistance in field populations of mosquito vectors of disease. The document will also be useful to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions.


Determining discriminating concentrations of insecticides for monitoring resistance in sand flies

Determining discriminating concentrations of insecticides for monitoring resistance in sand flies
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 62
Release: 2023-01-10
Genre: Medical
ISBN: 9240064419

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The document presents outcome of a WHO multi-centre study (2020–2022) performed by eight laboratories in different WHO regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations (DCs) for monitoring resistance in sand fly vectors of leishmaniases. It describes use of the WHO bottle bioassay as a new method for testing susceptibility of sand flies to insecticides that are not suitable for impregnation on filter papers and makes recommendations to WHO on monitoring of insecticide resistance in field populations of sand flies. It also proposes further research to test the new DCs for sand flies in other settings and conditions and to collect evidence from the national disease control programmes and share them with WHO for further assessment and revision of the DCs if required. The current edition of the WHO manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions will be revised using the recommendations made to WHO including for the new DCs for sand flies. The report will be useful to the national vector-borne disease control programmes and the research community for resistance monitoring, and to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions. Please send your suggestions and comments to [email protected] indicating the title of the report and the relevant section and page.


Standard operating procedure for testing the susceptibility of adult sand flies to insecticides in WHO bottle bioassays

Standard operating procedure for testing the susceptibility of adult sand flies to insecticides in WHO bottle bioassays
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 32
Release: 2023-07-11
Genre: Medical
ISBN: 9240074600

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This document contains the standard operating procedure (SOP) for evaluating the susceptibility of adult sand fly vectors (Phlebotomus spp. and Lutzomyia longipalpis) to insecticides in WHO bottle bioassays. Some species of sand flies are vectors of leishmaniases. The SOP includes instructions on preparing materials, exposing sand flies, and recording and interpreting test results. This procedure should be followed to test the susceptibility of sand flies to insecticides that are unstable and/or cannot be impregnated on usual Whatman No. 1 filter papers. This SOP will fulfil the long-awaited need of vector-borne disease control programmes in health ministries in countries endemic for or at risk of visceral and cutaneous leishmaniasis, researchers and the pesticide industry to monitor insecticide resistance in wild populations of sand fly vectors. It can be adapted to determine discriminating concentrations of new insecticide compounds with susceptible strains of sand fly vectors in laboratories.


Manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions

Manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 70
Release: 2022-06-22
Genre: Medical
ISBN: 9240051082

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Vector-borne diseases are major causes of sickness, disability and death worldwide. These diseases are caused by parasites, bacteria or viruses transmitted by various vectors, including mosquitoes, sandflies, fleas, ticks, lice and others. Insecticides form an essential part of vector control, the most widely used and effective strategy to reduce the burden of these diseases. Knowledge of vector resistance to insecticides is therefore crucial for the selection of effective vector control interventions. This document provides guidance on how to assess insecticide resistance in mosquito vectors and is aimed at field entomologists and biologists within ministries of health or partner institutions. It is also directed at programme managers and others in charge of designing and implementing vector control strategies who need to draw on resistance data to inform their decisions. Lastly, it can help researchers and the pesticide industry to assess, in a standardized way, vector resistance to compounds used in existing and new vector control products. It supersedes the “Test procedures for insecticide resistance monitoring in malaria vector mosquitoes, 2nd ed.” published in 2016.


Pesticide Resistance in Arthropods

Pesticide Resistance in Arthropods
Author: Richard Roush
Publisher: Springer Science & Business Media
Total Pages: 312
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 1468464299

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Bruce E. Tabashnik and Richard T. Roush Pesticide resistance is an increasingly urgent worldwide problem. Resistance to one or more pesticides has been documented in more than 440 species of insects and mites. Resistance in vectors of human dise8se, particularly malaria-transmit ting mosquitoes, is a serious threat to public health in many nations. Agricultural productivity is jeopardized because of widespread resistance in crop and livestock pests. Serious resistance problems are also evident in pests of the urban environ ment, most notably cockroaches. Better understanding of pesticide resistance is needed to devise techniques for managing resistance (Le. , slowing, preventing, or reversing development of resistance in pests and promoting it in beneficial natural enemies). At the same time, resistance is a dramatic example of evolution. Knowledge of resistance can thus provide fundamental insights into evolution, genetics, physiology, and ecology. Resistance management can help to reduce the harmful effects of pesticides by decreasing rates of pesticide use and prolonging the efficacy of environmentally safe pesticides. In response to resistance problems, the concentration or frequency of pesticide applications is often increased. Effective resistance management would reduce this type of increased pesticide use. Improved monitoring of resis tance would also decrease the number of ineffective pesticide applications that are made when a resistance problem exists but has not been diagnosed. Resistance often leads to replacement of one pesticide with another that is more expensive and less compatible with alternative controls.


Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases
Author: Michel Tibayrenc
Publisher: Elsevier
Total Pages: 1002
Release: 2024-07-19
Genre: Medical
ISBN: 0443288194

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Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. Takes an integrated approach to infectious diseases Provides the latest developments in the field of infectious diseases Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases Includes updated and revised contributions from leading authorities, along with six new chapters


Mealybugs and their Management in Agricultural and Horticultural crops

Mealybugs and their Management in Agricultural and Horticultural crops
Author: M. Mani
Publisher: Springer
Total Pages: 647
Release: 2016-02-24
Genre: Science
ISBN: 8132226771

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This book is a compilation of information on all basic aspects of mealybugs, as well as management strategies for mealybug species affecting different crop plants in different countries. It highlights the latest information on morphology, cytogenetics, taxonomy, molecular characterization, biology, damage, ecology, natural enemies, ant association, control measures, insecticide resistance and pheromones – essential aspects which will equip researchers to pursue further research on mealybugs. The book examines current trends in the management of mealybugs for a variety of agricultural and horticultural crops, forest plants and mulberry in different countries, while also addressing the negative effects of chemical control methods and presenting success stories of mealybug control that utilize their natural enemies. It offers a valuable guide for crop growers, government officials and other stakeholders in the industry, as well as researchers and students engaged in related research and development activities.


Resistance’ 91: Achievements and Developments in Combating Pesticide Resistance

Resistance’ 91: Achievements and Developments in Combating Pesticide Resistance
Author: I. Denholm
Publisher: Springer Science & Business Media
Total Pages: 390
Release: 1992-07-31
Genre: Nature
ISBN: 9781851668861

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The development of pesticide resistance in arthropod pests, plant pathogens and weeds can be viewed and studied from two contrasting perspectives. At a fundamental level, resistance provides an almost ideal example of adaptation to withstand severe environmental stress. Population geneticists, biochemists and, most recently, molecular biologists have cast considerable light on the nature of this adaptation in diverse taxonomic groups, and on factors determining its selection and spread within and between populations. Unlike most evolutionary phenomena, however, resistance is also of immediate practical and economic significance. Not only has the number of resistant species continued to increase inexorably, but there has been an alarming increase in the severity and extent of some resistance problems. Cases of organisms resisting virtually all available pesticides are by no means uncommon, and pose a formidable challenge in view of present difficulties in discovering and developing novel chemicals. Although most occurrences of resistance were initially monofactorial, resistance now frequently involves a suite of coexisting mechanisms that protect organisms against the same or different pesticide groups, and may even predispose them to resist new, as yet unused chemicals.


The Ecology Of Health And Disease In Ethiopia

The Ecology Of Health And Disease In Ethiopia
Author: Helmut Kloos
Publisher: Routledge
Total Pages: 505
Release: 2019-07-11
Genre: Social Science
ISBN: 1000316130

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This book examines prevailing human health problems in political, socioeconomic, cultural, and physical/biotic settings of health practitioners and planners in Ethiopia. It also evaluates modern and traditional health resources and examines the occurrence of nonvectored communicable diseases.