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Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications

Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications
Author: R. C. Sobti
Publisher: Springer Nature
Total Pages: 496
Release: 2021-11-30
Genre: Medical
ISBN: 9811651051

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This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.


COVID-19 Current Challenges and Future Perspectives

COVID-19 Current Challenges and Future Perspectives
Author: Anoop Kumar
Publisher: Bentham Science Publishers
Total Pages: 212
Release: 2021-03-03
Genre: Medical
ISBN: 9811498636

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COVID-19: Current Challenges and Future Perspectives informs readers about the current status of knowledge on COVID-19 infection. The book begins by presenting basic information about the history, epidemiology, pathogenesis, diagnosis, treatment and preventive measures against COVID-19. The second part of the book contains information about the repurposing of drugs, herbal medicines, and immunotherapy against COVID-19 infections. Integrating both general and advanced information about Sars-cov-2, this book updates a wide range of readers including students, researchers (virologists, pharmacologists), health care professionals (physicians, nurses, pharmacists, paramedics) and the general public on novel coronaviruses and COVID-19.


New Advances on Zika Virus Research

New Advances on Zika Virus Research
Author: Luis Martinez-Sobrido
Publisher: MDPI
Total Pages: 554
Release: 2019-04-02
Genre: Arctic medicine. Tropical medicine
ISBN: 3038977640

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Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.


Coronavirus Disease 2019 (COVID-19)

Coronavirus Disease 2019 (COVID-19)
Author: Shailendra K. Saxena
Publisher:
Total Pages:
Release: 2020
Genre: Coronavirus infections
ISBN: 9789811548154

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This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.


Stigma

Stigma
Author: Gerhard Falk
Publisher: Prometheus Books
Total Pages: 376
Release: 2010-04-06
Genre: Psychology
ISBN: 1615923969

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What is it in human nature that leads us to label some as insiders and stigmatize others as outsiders?Sociologist Gerhard Falk examines the social psychology that motivates this process of exclusion, focusing on the outcasts in contemporary American society and comparing current experience with examples from the past. Referring to the work of Emile Durkheim and Erving Goffman, Falk reviews the whole range of stigmatized people from the mentally ill to ordinary people with unpopular occupations, like undertakers and trash collectors. Amid the wide diversity of stigmatized persons, he finds two basic types of outsiders: the "existential" and the "achieved." The first group comprises those who are stigmatized because of their very existence, regardless of their specific actions: the mentally handicapped, for example. The second group describes those whose actions or life conditions have resulted in stigma: from high achievers (often subject to resentment) to criminals. Falk also looks at the ways in which writers past and present have dramatized stigmatized characters in literature.This fascinating overview of a long-standing and widespread social problem will be of interest to all those concerned about creating a more fair-minded society.


Lumpy Skin Disease

Lumpy Skin Disease
Author: Eeva S. M. Tuppurainen
Publisher: Springer
Total Pages: 99
Release: 2018-07-03
Genre: Medical
ISBN: 3319924117

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This book provides a comprehensive but concise overview on the economically important emerging cattle pox virus derived Lumpy Skin Disease, including the characteristics of causative agent, description of clinical signs in cattle, pathology and histopathology, immunity, geographical distribution, epidemiology and transmission pathways, control and eradication of the disease. In addition the recent developments in vaccination, mathematical modeling and risk assessment are discussed. Lumpy Skin Disease currently spreads aggressively across the Middle and Near East. The first incursion to the European Union territory occurred in Greece in autumn 2015. The book targets clinicians and field veterinarians in Lumpy Skin Disease affected regions, veterinary authorities as well as advanced students in veterinary medicine and virology.


Replication-Competent Reporter-Expressing Viruses

Replication-Competent Reporter-Expressing Viruses
Author: Luis Martinez-Sobrido
Publisher: MDPI
Total Pages: 339
Release: 2018-09-27
Genre: Biology (General)
ISBN: 3038422584

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This book is a printed edition of the Special Issue "Replication-Competent Reporter-Expressing Viruses" that was published in Viruses


Hospital-Based Health Technology Assessment

Hospital-Based Health Technology Assessment
Author: Laura Sampietro-Colom
Publisher: Springer
Total Pages: 397
Release: 2017-01-23
Genre: Medical
ISBN: 3319392050

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A timely work describing how localized hospital-based health technology assessment (HB-HTA) complements general, ‘arms-length’ HTA agency efforts, and what has been the collective global impact of HB-HTA across the globe. While HB-HTA has gained significant momentum over the past few years, expertise in the field, and information on the operation and organization of HB-HTA, has been scattered. This book serves to bring this information together to inform those who are currently working in the field of HTA at the hospital, regional, national or global level. In addition, this book is intended for decision-makers and policy-makers with a stake in determining the uptake and decommissioning of new and established technologies in the hospital setting. HTA has traditionally been performed at the National/Regional level by HTA Agencies, typically linked to governments. Yet hospitals are the main entry door for most health technologies (HTs). Hospital decision-makers must undertake multiple high stakes investment and disinvestment decisions annually for innovative HTs, usually without adequate information. Despite the existence of arms-length HTA Agencies, inadequate information is available to hospital decision-makers either because relevant HTA reports are not yet released at the time of entry of new technologies to the field, or because even when the report exists, the information contained is insufficient to clarify the contextualized informational needs of hospital decision makers. Therefore, there has recently been a rising trend toward hospital-based HTA units and programs. These units/programs complement the work of National/Regional HTA Agencies by providing the key and relevant evidence needed by hospital decision makers in their specific hospital context, and within required decision-making timelines. The emergence of HB-HTA is creating a comprehensive HTA ecosystem across health care levels, which creates better bridges for knowledge translation through relevance and timeliness.


Electrochemical Biosensors

Electrochemical Biosensors
Author: Serge Cosnier
Publisher: CRC Press
Total Pages: 405
Release: 2015-01-26
Genre: Science
ISBN: 9814411477

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Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy


The Biopsychosocial Model of Health and Disease

The Biopsychosocial Model of Health and Disease
Author: Derek Bolton
Publisher: Springer
Total Pages: 149
Release: 2019-03-28
Genre: Psychology
ISBN: 3030118991

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This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.