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Cytoskeleton of the Nervous System

Cytoskeleton of the Nervous System
Author: Ralph A. Nixon
Publisher: Springer Science & Business Media
Total Pages: 775
Release: 2011-02-04
Genre: Medical
ISBN: 1441967877

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This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.


Neuronal Cytoskeleton

Neuronal Cytoskeleton
Author: Hirokawa
Publisher: CRC Press
Total Pages: 360
Release: 1994-01-12
Genre: Science
ISBN: 9780849377419

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This book discusses the primary functions of microtubule-associated proteins (MAPs) such as MAP2 and tau in neuronal morphogenesis, as well as relationships between neuronal differentiation and the expression of neuronal intermediate filaments (nestin, alpha internexin, and neurofilament triplet proteins). It emphasizes the importance of several cytoskeletal proteins for neuronal differentiation and morphogenesis, organelle transport, and synaptic functions. The book considers the involvement of tau MAPs in the formation of paired helical filaments in Alzheimer's disease, and it examines the mechanisms of organelle transports and molecular motors such as kinesin, braindynein, and kinesin superfamily proteins. Cytoskeletal proteins involved in synaptic formation and transmitter release and new synaptic junctional-associated proteins are explored as well.


Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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The Cytoskeleton

The Cytoskeleton
Author: Rolf Dermietzel
Publisher: Humana Press
Total Pages: 376
Release: 2016-05-01
Genre: Medical
ISBN: 9781493959372

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This informative Neuromethods series book surveys the cytoskeleton, and offers detailed protocols on emerging techniques including in vivo and in vitro imaging and preparative strategies for isolation of cytoskeletal components of the central nervous system.


The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon

The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon
Author:
Publisher: Academic Press
Total Pages: 552
Release: 2016-01-12
Genre: Science
ISBN: 0128033541

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The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field


Nanoneuroscience

Nanoneuroscience
Author: Nancy J. Woolf
Publisher: Springer Science & Business Media
Total Pages: 290
Release: 2009-12-04
Genre: Technology & Engineering
ISBN: 3642035841

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Nanoneuroscience is the study of computationally relevant biomolecules found inside neurons. Because of recent technological advances at the nanometer scale, scientists have at their disposal increasingly better ways to study the brain and the biophysics of its molecules. This book describes how biomolecules contribute to the operations of synapses and perform other computationally relevant functions inside dendrites. These biomolecular operations considerably expand the brain-computer analogy - endowing each neuron with the processing power of a silicon-based multiprocessor. Amazingly, the brain contains hundreds of billions of neurons.


The Neuronal Cytoskeleton

The Neuronal Cytoskeleton
Author: Robert D. Burgoyne
Publisher: Wiley-Liss
Total Pages: 352
Release: 1991-02-27
Genre: Medical
ISBN:

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This text examines the organization and structure of cytoskeletal proteins, their regulation and precise roles in neuronal development and function. Using a wide range of techniques including ultrastructural, biochemical and molecular biological approaches, the chapters examine such particular components as microtubule-associated proteins, microtubules and microtubule assembly, actin and related proteins and neurofilaments. Also describes the functional importance of the neuronal cytoskeleton during neuronal development and in axonal transport and neurotransmitter release. Designed to stand alone as self-contained reviews of a particular aspect of the field, the chapters amount to a comprehensive view of the neuronal cytoskeleton and its functions.