Cytokines And The Brain PDF Download
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Author | : |
Publisher | : Elsevier |
Total Pages | : 609 |
Release | : 2008-06-18 |
Genre | : Science |
ISBN | : 0080559352 |
Download Cytokines and the Brain Book in PDF, ePub and Kindle
This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment. *Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease*Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease*Includes novel approaches to the treatment of CNS disorders based on new experimental data*Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment
Author | : Armen A. Galoyan |
Publisher | : Springer Science & Business Media |
Total Pages | : 192 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1441988939 |
Download Brain Neurosecretory Cytokines Book in PDF, ePub and Kindle
From the reviews: ""Brain Neurosecretory Cytokines is an excellent book, a veritable goldmine of information, at the cutting edge of neuroscience. It should stimulate ideas for future directions in neuroscience for years to come. This volume should be highly useful for medical libraries, neuroscientists, endocrinologists and graduate students in these fields."" (Arthur S. Brecher, TRENDS in Endocrinology & Metabolism, Vol. 16 (6), 2005)
Author | : Nancy J. Rothwell |
Publisher | : Springer Science & Business Media |
Total Pages | : 216 |
Release | : 2013-03-09 |
Genre | : Medical |
ISBN | : 1461596955 |
Download Cytokines in the Nervous System Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 5 |
Release | : 2005 |
Genre | : |
ISBN | : |
Download Cytokines in the Brain Book in PDF, ePub and Kindle
Author | : Donald W. Pfaff |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2016-10-27 |
Genre | : Medical |
ISBN | : 9781493934737 |
Download Neuroscience in the 21st Century Book in PDF, ePub and Kindle
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Author | : Allan Siegel |
Publisher | : Springer Science & Business Media |
Total Pages | : 437 |
Release | : 2008-11-09 |
Genre | : Medical |
ISBN | : 0387848517 |
Download The Neuroimmunological Basis of Behavior and Mental Disorders Book in PDF, ePub and Kindle
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.
Author | : Richard M. Ransohoff |
Publisher | : CRC Press |
Total Pages | : 379 |
Release | : 2005-10-31 |
Genre | : Medical |
ISBN | : 1420039849 |
Download Cytokines and the CNS Book in PDF, ePub and Kindle
Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelera
Author | : Nancy J. Rothwell |
Publisher | : Elsevier |
Total Pages | : 216 |
Release | : 2013-10-22 |
Genre | : Science |
ISBN | : 1483287769 |
Download Interleukin-1 in the Brain Book in PDF, ePub and Kindle
Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration.
Author | : Robert Dantzer |
Publisher | : Springer Science & Business Media |
Total Pages | : 334 |
Release | : 1999-07-31 |
Genre | : Medical |
ISBN | : 0306461358 |
Download Cytokines, Stress, and Depression Book in PDF, ePub and Kindle
Until a few years ago, cytokines were only known to immunologists; now these molecules have burst upon neurosciences and permeated several avenues of current research. This book examines the possible role of cytokines in mental depression, based on recent clinical and experimental data, and constitutes the first attempt to make a synthesis between the exciting new developments in cytokine research and their implications for the pathophysiology of mental disorders.
Author | : Ziad Kronfol |
Publisher | : Springer Science & Business Media |
Total Pages | : 436 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 146150323X |
Download Cytokines and Mental Health Book in PDF, ePub and Kindle
Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational", bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of cytokines in neuropsychiatric disorders such as major depression, schizophrenia and Alzheimer's disease. The book offers different things to different people. It should be of great interest to neuroscientists and immunologists working in the field of psychoneuroimmunology. It would also greatly benefit mental health professionals including psychiatrists, psychologists and clinicians of diverse background who are interested in mind-body medicine.