Cooperativity And Regulation In Biochemical Processes PDF Download
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Author | : Arieh Y. Ben-Naim |
Publisher | : Springer Science & Business Media |
Total Pages | : 358 |
Release | : 2013-03-09 |
Genre | : Science |
ISBN | : 147573302X |
Download Cooperativity and Regulation in Biochemical Processes Book in PDF, ePub and Kindle
This is the first book that attempts to study the origin of cooperatvity in binding systems from the molecular point of view. The molecular approach provides a deeper insight into the mechanism of cooperativity and regulation, than the traditional phenomenological approach. This book uses the tools of statistical mechanics to present the molecular theory of cooperativity. Cooperativity is used in a variety of processes-such as loading and unloading of oxygen at relatively small pressure differences; maintaining an almost constant concentration of various compounds in living cells; and switching on and off the reading of genetic information. This book may be used as a textbook by graduate students in Chemistry, Biochemistry and Biophysics, and will also be of interest to researchers in theoretical biochemistry.
Author | : Arieh Ben-Naim |
Publisher | : |
Total Pages | : 368 |
Release | : 2014-01-15 |
Genre | : |
ISBN | : 9781475733037 |
Download Cooperativity and Regulation in Biochemical Processes Book in PDF, ePub and Kindle
Author | : Daniel Goldfarb |
Publisher | : McGraw Hill Professional |
Total Pages | : 400 |
Release | : 2010-12-06 |
Genre | : Science |
ISBN | : 0071633650 |
Download Biophysics DeMYSTiFied Book in PDF, ePub and Kindle
Learn BIOPHYSICS without expending a lot of ENERGY! Interested in unraveling the physics of living things? Here's your starting point. Biophysics Demystified is the fast and easy way to understand this fascinating topic. Written in a step-by-step format, this practical guide begins with an introduction to the science of biophysics, covering biophysical techniques and applications. Next, you'll learn the principles of physics, biology, and chemistry required to understand biophysics, including free energy, entropy, and statistical mechanics. Biomolecules and the forces that influence their structure and conformation are also covered, as are protein, nucleic acid, and membrane biophysics. Detailed examples and concise explanations make it easy to understand the material, and end-of-chapter quizzes and a final exam help reinforce key concepts. It's a no-brainer! You'll get: Molecular, subcellular, physiological, anatomical, and environmental biophysics The laws of thermodynamics as they apply to biophysical systems Forces affecting conformation in biological molecules The composition and structure of carbohydrates, lipids, proteins, and nucleic acids The fluid mosaic model Simple enough for a beginner, but challenging enough for an advanced student, Biophysics Demystified makes this interdisciplinary subject easy to master.
Author | : Jo M. Holt |
Publisher | : Elsevier |
Total Pages | : 315 |
Release | : 2004-04-02 |
Genre | : Science |
ISBN | : 0080497179 |
Download Energetics of Biological Macromolecules, Part D Book in PDF, ePub and Kindle
This volume focuses on the cooperative binding aspects of energetics in biological macromolecules. Methodologies such as NMR, small-angle scattering techniques for analysis, calorimetric analysis, fluorescence quenching, and time resolved FRET measurements are discussed. *Methods for Evaluating Cooperativity in a Dimeric Hemoglobin*Multiple-Binding of Ligands to a Linear Biopolymer*Fluorescence Quenching Methods to Study Protein-Nucleic Acid Interactions*Linked Equilibria in Biotin Repressor Function: Thermodynamic, Structural and Kinetic Analysis
Author | : David Fell |
Publisher | : |
Total Pages | : 301 |
Release | : 1997 |
Genre | : |
ISBN | : |
Download Understanding the Control of Metabolism Book in PDF, ePub and Kindle
Author | : Roland N. Pittman |
Publisher | : Biota Publishing |
Total Pages | : 117 |
Release | : 2016-08-18 |
Genre | : Medical |
ISBN | : 1615047212 |
Download Regulation of Tissue Oxygenation, Second Edition Book in PDF, ePub and Kindle
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author | : R.D. O'Brien |
Publisher | : Springer Science & Business Media |
Total Pages | : 356 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1468409794 |
Download General Principles and Procedures Book in PDF, ePub and Kindle
The following remarks are intended to serve as an introduction to this particular volume as well as to the whole series of volumes of which this is the first. The intent of the series is to provide an authentic and relatively complete statement about the status of our understanding of the receptors. The models we had in mind while developing this series are The Enzymes, The Proteins, and comparable groups of books. The receptors have received a degree of importance and richness of understanding that makes them deserving of comprehensive and complete coverage. The study of these molecules, which may well include such diverse items as the receptors for hormones, neurohumors, pheromones, taste, and many other chemical signals, have a great deal in common, so that the student of any one of them will wish to know the status of research about the others. This com monality is in part substantive, and in part practical and procedural. Substantively, the receptors are all macromolecules whose function is to re ceive some form of chemical signal and transduce it to a form which is usable by the receiving cell. In this way, a chemical signal may lead to a neural response, to the turning-on of a cell's chromosomes, or to the activation of some enzymic apparatus to produce or release a substance. Because most of these processes are noncatalytic, special techniques not previously commonplace in biochemistry have been developed in order to study the receptors.
Author | : Alan Fersht |
Publisher | : World Scientific Publishing Company |
Total Pages | : 0 |
Release | : 2017 |
Genre | : Catalysis |
ISBN | : 9789813225190 |
Download Structure and Mechanism in Protein Science Book in PDF, ePub and Kindle
The three-dimensional structure of proteins -- Chemical catalysis -- The basic equations of enzyme kinetics -- Measurement and magnitude of individual rate constants -- The pH dependence of enzyme catalysis -- Practical methods for kinetics and equilibria -- Detection of intermediates in enzymatic reactions -- Stereochemistry of enzymatic reactions -- Active-site-directed and enzyme-activated irreversible inhibitors : "affinity labels" and "suicide inhibitors" -- Conformational change, allosteric regulation, motors, and work -- Forces between molecules, and binding energies -- Enzyme-substrate complementarity and the use of binding energy in catalysis -- Specificity and editing mechanisms -- Recombinant DNA technology -- Protein engineering -- Case studies of enzyme structure and mechanism -- Protein stability -- Kinetics of protein folding -- Folding pathways and energy landscapes.
Author | : Harald Tschesche |
Publisher | : Walter de Gruyter |
Total Pages | : 379 |
Release | : 2011-12-23 |
Genre | : Science |
ISBN | : 3110252368 |
Download Methods in Protein Biochemistry Book in PDF, ePub and Kindle
This book presents a survey of recent developments in protein biochemistry. Top researchers in the field of protein biochemistry describe modern methods to address the challenges of protein purification by three-phase partitioning, and their folding and degradation by the functions of chaperones. The significance of peptide purity for fibril formation is addressed as well as the use of target oriented peptide arrays in palliative approaches in mucoviszidose. The design and application of protein epitope mimetics just as the structural resolving of the misfolding of various mutant proteins in serpinopathies enlarge our tools in resolving pathophysiological imbalances.
Author | : Rob Phillips |
Publisher | : Garland Science |
Total Pages | : 1089 |
Release | : 2012-10-29 |
Genre | : Science |
ISBN | : 1134111584 |
Download Physical Biology of the Cell Book in PDF, ePub and Kindle
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that