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| Author | : Cassandra Clare |
| Publisher | : Simon and Schuster |
| Total Pages | : 720 |
| Release | : 2017-05-23 |
| Genre | : Young Adult Fiction |
| ISBN | : 1442468408 |
Emma is torn between her passion for Julian and her need to protect him from the consequences of a forbidden romantic partnership, a situation challenged by her relationship with Mark and his efforts to regain his Shadowhunter capabilities.
| Author | : Mia Asher |
| Publisher | : Createspace Independent Publishing Platform |
| Total Pages | : 0 |
| Release | : 2013-10-28 |
| Genre | : Erotic stories |
| ISBN | : 9781492131014 |
One glance was all it took... I'm a cheater. I'm a liar. My whole life is a mess. I love a man. No, I love two men... I think. One makes love to me. The other sets me on fire. One is my rock. The other is my kryptonite. I'm broken, lost, and disgusted with myself. But I can't stop. This is my story. My broken love story.
| Author | : Charles H. Spurgeon |
| Publisher | : Whitaker House |
| Total Pages | : 392 |
| Release | : 2017-01-03 |
| Genre | : Religion |
| ISBN | : 1629110795 |
"Ask anything in my name, I will do it." (John 14:14) Charles H. Spurgeon supplies daily deposits of God's promises into the reader's personal bank of faith. He urges the reader to view each Bible promise as a check written by God, which can be cashed by personally endorsing it and receiving the gift it represents!
| Author | : Yvonne Conde |
| Publisher | : Routledge |
| Total Pages | : 281 |
| Release | : 2002-05-03 |
| Genre | : Political Science |
| ISBN | : 1135957487 |
First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.
| Author | : Joy A. Cavagnaro |
| Publisher | : CRC Press |
| Total Pages | : 952 |
| Release | : 2021-11-26 |
| Genre | : Medical |
| ISBN | : 1000471853 |
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
| Author | : John Butt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 533 |
| Release | : 2012-12-06 |
| Genre | : Foreign Language Study |
| ISBN | : 1461583683 |
(abridged and revised) This reference grammar offers intermediate and advanced students a reason ably comprehensive guide to the morphology and syntax of educated speech and plain prose in Spain and Latin America at the end of the twentieth century. Spanish is the main, usually the sole official language of twenty-one countries,} and it is set fair to overtake English by the year 2000 in numbers 2 of native speakers. This vast geographical and political diversity ensures that Spanish is a good deal less unified than French, German or even English, the latter more or less internationally standardized according to either American or British norms. Until the 1960s, the criteria of internationally correct Spanish were dictated by the Real Academia Espanola, but the prestige of this institution has now sunk so low that its most solemn decrees are hardly taken seriously - witness the fate of the spelling reforms listed in the Nuevas normas de prosodia y ortograjia, which were supposed to come into force in all Spanish-speaking countries in 1959 and, nearly forty years later, are still selectively ignored by publishers and literate persons everywhere. The fact is that in Spanish 'correctness' is nowadays decided, as it is in all living languages, by the consensus of native speakers; but consensus about linguistic usage is obviously difficult to achieve between more than twenty independent, widely scattered and sometimes mutually hostile countries. Peninsular Spanish is itself in flux.
| Author | : M. Keith Booker |
| Publisher | : Praeger |
| Total Pages | : 726 |
| Release | : 2007-10-30 |
| Genre | : Performing Arts |
| ISBN | : |
Since the first Superman film came to the screen in 1978, films adapted from comics have become increasingly important as a film form. Since that time, advances in computer-generated special effects have significantly improved the ability of film to capture the style and action of comics, producing film such as X-men and Spider-man.
| Author | : Carol Brunson Day |
| Publisher | : Ingram |
| Total Pages | : 466 |
| Release | : 2004-11-01 |
| Genre | : Child development |
| ISBN | : 9780975914007 |
| Author | : Cirilo Villaverde |
| Publisher | : Oxford University Press |
| Total Pages | : 545 |
| Release | : 2005-09-29 |
| Genre | : Literary Collections |
| ISBN | : 0199725233 |
Cecilia Valdés is arguably the most important novel of 19th century Cuba. Originally published in New York City in 1882, Cirilo Villaverde's novel has fascinated readers inside and outside Cuba since the late 19th century. In this new English translation, a vast landscape emerges of the moral, political, and sexual depravity caused by slavery and colonialism. Set in the Havana of the 1830s, the novel introduces us to Cecilia, a beautiful light-skinned mulatta, who is being pursued by the son of a Spanish slave trader, named Leonardo. Unbeknownst to the two, they are the children of the same father. Eventually Cecilia gives in to Leonardo's advances; she becomes pregnant and gives birth to a baby girl. When Leonardo, who gets bored with Cecilia after a while, agrees to marry a white upper class woman, Cecilia vows revenge. A mulatto friend and suitor of hers kills Leonardo, and Cecilia is thrown into prison as an accessory to the crime. For the contemporary reader Helen Lane's masterful translation of Cecilia Valdés opens a new window into the intricate problems of race relations in Cuba and the Caribbean. There are the elite social circles of European and New World Whites, the rich culture of the free people of color, the class to which Cecilia herself belonged, and then the slaves, divided among themselves between those who were born in Africa and those who were born in the New World, and those who worked on the sugar plantation and those who worked in the households of the rich people in Havana. Cecilia Valdés thus presents a vast portrait of sexual, social, and racial oppression, and the lived experience of Spanish colonialism in Cuba.
| Author | : Luis Aragones |
| Publisher | : McGraw Hill Professional |
| Total Pages | : 304 |
| Release | : 2014-11-14 |
| Genre | : Foreign Language Study |
| ISBN | : 0071839003 |
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. What you need to know to master advanced Spanish grammar McGraw-Hill: Advanced Spanish Grammar guides you through this often-difficult subject, clearly explaining complex grammar ideas and giving you the practice you need to reach your language goals. Written in clear, accessible Spanish, each chapter introduces one grammar topic followed by skill-building exercises, allowing you to learn and study at your own pace. At the end of this workbook, you will have mastered grammar areas such as gender, articles, adjectives, possessives, and verb tenses and will have gained the ultimate confidence in your Spanish grammar skills. Features: 106 units, each presenting one topic in a bite-sized,two-page format More than 400 exercises that give you real confidence in your new language skills A comprehensive grammar glossary highlighting essential concepts A bilingual glossary featuring hundreds of terms for quick reference Numerous illustrations and usage examples showing Spanish grammar in context McGraw-Hill: Advanced Spanish Grammar is the third book in a three-part series. McGraw-Hill: Beginning Spanish Grammar and McGraw-Hill: Intermediate Spanish Grammar are also available for less experienced Spanish-language learners.
