Control and Manipulation of Calcium Movement
Author | : James R. Parratt |
Publisher | : |
Total Pages | : 408 |
Release | : |
Genre | : |
ISBN | : 9780783772196 |
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Author | : James R. Parratt |
Publisher | : |
Total Pages | : 408 |
Release | : |
Genre | : |
ISBN | : 9780783772196 |
Author | : Biological Council. Co-ordinating Committee for Symposia on Drug Action |
Publisher | : Raven Press (ID) |
Total Pages | : 420 |
Release | : 1985 |
Genre | : Medical |
ISBN | : |
Author | : Biological Council. Symposium ( |
Publisher | : |
Total Pages | : 394 |
Release | : 1985 |
Genre | : |
ISBN | : |
Author | : Gary Fiskum |
Publisher | : Springer Science & Business Media |
Total Pages | : 613 |
Release | : 2013-04-17 |
Genre | : Medical |
ISBN | : 1468455982 |
A widespread appreciation for the role that calcium plays in cell physiology and patho physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D. C. The participants in this unique meeting rep resented diverse fields of basic and clinical research, such as molecular physiology, oncology, molecular genetics, cardiology, bioenergetics, pathology, and endocrinology. The content of the proceedings of the symposium represents work in these and other areas of biomedical research. Organization of the book is aimed at striking a balance between the biochemistry 2 and physiology of normal cell Ca + metabolism and the pathological consequences of al 2 terations in cell Ca + homeostasis. The first section of the book is devoted to the transport mechanisms responsible for 2 2 regulating intracellular Ca + and the pharmacological modalities for controlling cell Ca + . Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels. The second section covers the exciting relationships between phosphoinositide metab 2 olism, signal transduction, and cell Ca + metabolism. This section begins with an eloquent overview by Professor Michael Berridge, who was the keynote speaker at the symposium and the recipient of the scientific merit award.
Author | : Robert E. Garfield |
Publisher | : Routledge |
Total Pages | : 454 |
Release | : 2019-06-12 |
Genre | : Medical |
ISBN | : 0429523874 |
Published in 1994: The Editors have outlines many advances in the field of uterine physiology in hopes of furthering the science.
Author | : Juliusz Ashot Kozak |
Publisher | : CRC Press |
Total Pages | : 343 |
Release | : 2017-07-14 |
Genre | : Science |
ISBN | : 149875273X |
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Author | : George Poste |
Publisher | : Springer Science & Business Media |
Total Pages | : 441 |
Release | : 2013-11-11 |
Genre | : Medical |
ISBN | : 146845062X |
Author | : Richard Nathan |
Publisher | : Elsevier |
Total Pages | : 341 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 0323155189 |
Cardiac Muscle: The Regulation of Excitation and Contraction is a 12-chapter text that covers the research studies on characterizing the ionic and molecular mechanisms that regulate excitation and contraction of cardiac muscle. This book describes first the ionic currents underlying diastolic depolarization and pacing of the heart. The discussions then shift to the mechanisms of action of calcium-channel antagonists; the regulation of calcium influx by indigenous factors, such as voltage- or calcium-mediated inactivation; the identification of fixed negative charges on the surface of the sarcolemma; and the regulation of gating and permeability of ion channels by these charges. These topics are followed by examining the molecular and ionic mechanisms that underlie the electrophysiologic actions of adrenergic and cholinergic neurotransmitters and peptide hormones. This text further explores the theoretical and experimental studies of the sodium-calcium exchange process, its stoichiometry, and how the exchanger might contribute to current flow during or after the action potential. Other chapters consider the mechanism of twitch and tonic tension regulation by cardiac glycosides and intracellular sodium and how toxic concentrations induce cardiac arrhythmias. A chapter highlights the identification of sarcolemmal binding sites for calcium, the likelihood that such binding or the release of calcium from the sarcoplasmic reticulum plays a role in the regulation of contraction and the release of calcium from the sarcoplasmic reticulum. The remaining chapters deal with the structural similarities among calcium-binding proteins of the contractile apparatus and the calcium channel, and the regulation of contraction by calcium-binding proteins. Physiologists, pathophysiologists, clinicians, researchers, and students who are interested in heart’s function will find this book invaluable.
Author | : Dipak K. Das |
Publisher | : CRC Press |
Total Pages | : 534 |
Release | : 1992-10-16 |
Genre | : Medical |
ISBN | : 9780849345555 |
Pathophysiology of Reperfusion Injury presents the first integrated summary of the important areas of reperfusion injury. By covering reperfusion injury in the heart, lungs, liver, kidneys, and small bowel, the book demonstrates the interrelationships of these various aspects and concludes that they are all part of a natural and integrated whole. The leading investigators in the field address the potential biochemical, cellular, and molecular mechanisms of reperfusion injury, which will benefit all researchers working in this field.
Author | : Mark I. M. Noble |
Publisher | : Cambridge University Press |
Total Pages | : 389 |
Release | : 1992-08-27 |
Genre | : Medical |
ISBN | : 0521400228 |
This 1992 volume examines the important relationship, initially studied in 1871 by Bowditch, between the strength of the heartbeat and the interval between beats.