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Concepts and Applications in Veterinary Toxicology

Concepts and Applications in Veterinary Toxicology
Author: PK Gupta
Publisher: Springer
Total Pages: 350
Release: 2019-08-12
Genre: Medical
ISBN: 3030222500

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This book: “Concepts and Applications in Veterinary Toxicology: An Interactive Guide”: covers a broad spectrum of topics related to students specializing in veterinary toxicology and for veterinary medical practitioners. Since the major emphasis of the book is to teach veterinary students, therefore more attention has been given to common toxicants to which several species are exposed including pet animals. The subject of veterinary toxicology is complicated greatly by the wide variations in responses of domestic, companion, aquatic, wild, and zoo species to toxicants. Therefore, emphasis has also been given to species variation and diagnostic toxicology including clinical management that is more relevant to veterinary profession. Key Features · Highlights specialized topics essential for veterinary specialists. · Covers a variety of common toxicants to which several species including pet animals are exposed. · Includes sample questions and answers that are extremely valuable for students, clinical pharmacists, teachers, and academicians in preparing for their board and other examinations.


Concepts in Toxicology

Concepts in Toxicology
Author: John H Duffus
Publisher: Royal Society of Chemistry
Total Pages: 189
Release: 2009-10-01
Genre: Science
ISBN: 1847559751

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Toxicology has never been more important. Advances in chemistry and technology offering improvements in the quality of human life become ever more rapid, bringing with them the potential for new toxicity hazards. This has led to legislation requiring toxicity testing and risk assessment for all chemicals and their uses. The new REACH (Risk Evaluation and Authorization of Chemicals) Regulation has profound economic consequences because, without official authorization, a chemical cannot be marketed. This book explains, in depth, the ideas underlying current advances in toxicology and its application in regulating and ensuring the safe use of chemicals. Sometimes old ideas have become assumptions that have become embedded in related laws and regulation, even though the thinking of toxicologists has moved on in line with developments in science. This leads to confusion in public understanding that the book should dispel. There are also fundamental ideas in toxicology that are not well understood concerning the concepts of hazard and risk and even about what constitutes a chemical. For many people the word 'chemical' describes manmade substances only. In fact, it is correctly applied to all substances that exist, from pure elements to the most complex biological molecules in food and medicines. This is further complicated by the complex distinction between the descriptors, 'toxic' and 'nontoxic'. Developments in epigenetics are revolutionizing our understanding of mutagenicity and carcinogenicity. Improved understanding of apoptosis and necrosis leads to improved interpretation of potentially toxic effects at the cellular level. The recently defined term 'chemical speciation' is driving more targeted research on the toxicity of inorganic chemicals. This book explains the concepts implied by key toxicological terms using diagrams to illustrate the relationships between them. It is an essential aid to understanding the new demands from regulators of risk assessment and to the implementation of appropriate risk management.


Concepts in Toxicology

Concepts in Toxicology
Author: John H. Duffus
Publisher: Royal Society of Chemistry
Total Pages: 189
Release: 2009
Genre: Medical
ISBN: 0854041575

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This is a reference for those who need to understand the fundamental toxicological concepts that underlie both the scientific development of the subject and its practical applicaton in regulation and management of chemical safety.


Fundamentals of Toxicology

Fundamentals of Toxicology
Author: PK Gupta
Publisher: Academic Press
Total Pages: 422
Release: 2016-08-26
Genre: Medical
ISBN: 0128054034

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Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology


Biological Concepts and Techniques in Toxicology

Biological Concepts and Techniques in Toxicology
Author: Jim E. Riviere
Publisher: CRC Press
Total Pages: 412
Release: 2006-03-06
Genre: Medical
ISBN: 1420018442

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Highlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicol


Mechanisms and Concepts in Toxicology

Mechanisms and Concepts in Toxicology
Author: W. Norman Aldridge
Publisher: CRC Press
Total Pages: 270
Release: 1996-02-15
Genre: Medical
ISBN: 9780748404131

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Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.


Forensic Toxicology

Forensic Toxicology
Author: Nicholas T. Lappas
Publisher: Academic Press
Total Pages: 545
Release: 2021-10-22
Genre: Medical
ISBN: 0128192879

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The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Also included in the second edition is a Unit focused on the forensic toxicology of individual drugs of abuse. Includes significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases


An Introduction to Toxicology

An Introduction to Toxicology
Author: Philip C. Burcham
Publisher: Springer Science & Business Media
Total Pages: 338
Release: 2013-11-19
Genre: Medical
ISBN: 144715553X

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This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​


Concepts In Inhalation Toxicology

Concepts In Inhalation Toxicology
Author: Roger O. McClellan
Publisher: CRC Press
Total Pages: 678
Release: 1995-09-25
Genre: Medical
ISBN: 9781439805572

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Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.


Small Animal Toxicology - E-Book

Small Animal Toxicology - E-Book
Author: Michael E. Peterson
Publisher: Elsevier Health Sciences
Total Pages: 928
Release: 2013-08-07
Genre: Medical
ISBN: 0323241980

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Diagnose and determine treatment for toxic exposures in small animals with this quick reference! Small Animal Toxicology, 3rd Edition covers hundreds of potentially toxic substances, providing the information you need to manage emergency treatment and prevent poisonings in companion animals. To help you identify an unknown poison, this guide provides a list of potential toxins based on clinical signs or symptoms. It also includes a NEW color insert with 85 full-color photographs of toxic plants and of lesions associated with various poisonings. Written by respected veterinarian Michael E. Peterson and board-certified veterinary toxicologist Patricia A. Talcott, along with a team of expert contributors, this edition covers a wide variety of topics including toxicodynamics, toxicokinetics, effective history taking, recognizing clinical signs of toxic exposures, managing emergencies, and supportive care of the poisoned patient. Comprehensive coverage of toxins/poisons includes the full range of substances from acetaminophen to zinc, including home products, prescription medicines, recreational drugs, and more. Guidelines to evaluation, diagnosis and treatment include examinations of the source, toxic dose, toxicokinetics, clinical signs, minimum database, confirming tests, treatment progress and differential diagnosis for each specific toxicant. Coverage of common poisonous substances includes grapes and raisins, nicotine, mercury, mushrooms, Christmas-time plants, and snake and spider venoms. Toxicological Concepts section provides information on toxicologic principles such as history taking, providing supportive care, and managing emergency treatment. General Exposures section addresses nontraditional toxicology such as indoor environmental air, pesticides, pharmaceuticals, and toxicities in pregnant and lactating animals. Miscellaneous Toxicant Groups section covers commonly encountered specific toxicants, the proper use of diagnostic laboratories, use of human poison control centers, and antidotes for specific toxins. More than 50 international contributors provide up-to-date, authoritative advice on treating poisonings and intoxications. 8 NEW chapters cover topics including legal considerations in toxicology cases, responding to mass exposures, and poisonings in birds, small mammals, and geriatric patients. NEW color insert shows 85 of the most commonly encountered toxic substances for at-a-glance identification. UPDATED Signs and Symptoms index makes it easier to find information on a toxic agent by presenting signs rather than requiring the formulation of a diagnosis. UPDATED information on agents most likely to cause a toxic reaction includes natural flea products and an expanded section on human medications. NEW quick-access format with bold headings and convenient tables and boxes allows quick retrieval of information in emergency situations.