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Introduction to Computational Proteomics

Introduction to Computational Proteomics
Author: Golan Yona
Publisher: CRC Press
Total Pages: 769
Release: 2010-12-09
Genre: Mathematics
ISBN: 1420010778

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Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie


Introduction to Computational Proteomics

Introduction to Computational Proteomics
Author: Golan Yona
Publisher: CRC Press
Total Pages: 545
Release: 2010-12-09
Genre: Mathematics
ISBN: 1000738272

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Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie


Computational Methods for Mass Spectrometry Proteomics

Computational Methods for Mass Spectrometry Proteomics
Author: Ingvar Eidhammer
Publisher: John Wiley & Sons
Total Pages: 296
Release: 2008-02-28
Genre: Medical
ISBN: 9780470724293

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Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. Computational Methods for Mass Spectrometry Proteomics describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. The book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists. Computational Methods for Mass Spectrometry Proteomics is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field.


Systems Biology and Computational Proteomics

Systems Biology and Computational Proteomics
Author: Trey Ideker
Publisher: Springer Science & Business Media
Total Pages: 138
Release: 2007-07-20
Genre: Science
ISBN: 3540730591

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This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.


Computational and Statistical Methods for Protein Quantification by Mass Spectrometry

Computational and Statistical Methods for Protein Quantification by Mass Spectrometry
Author: Ingvar Eidhammer
Publisher: John Wiley & Sons
Total Pages: 290
Release: 2012-12-10
Genre: Mathematics
ISBN: 111849377X

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The definitive introduction to data analysis in quantitative proteomics This book provides all the necessary knowledge about mass spectrometry based proteomics methods and computational and statistical approaches to pursue the planning, design and analysis of quantitative proteomics experiments. The author’s carefully constructed approach allows readers to easily make the transition into the field of quantitative proteomics. Through detailed descriptions of wet-lab methods, computational approaches and statistical tools, this book covers the full scope of a quantitative experiment, allowing readers to acquire new knowledge as well as acting as a useful reference work for more advanced readers. Computational and Statistical Methods for Protein Quantification by Mass Spectrometry: Introduces the use of mass spectrometry in protein quantification and how the bioinformatics challenges in this field can be solved using statistical methods and various software programs. Is illustrated by a large number of figures and examples as well as numerous exercises. Provides both clear and rigorous descriptions of methods and approaches. Is thoroughly indexed and cross-referenced, combining the strengths of a text book with the utility of a reference work. Features detailed discussions of both wet-lab approaches and statistical and computational methods. With clear and thorough descriptions of the various methods and approaches, this book is accessible to biologists, informaticians, and statisticians alike and is aimed at readers across the academic spectrum, from advanced undergraduate students to post doctorates entering the field.


Systems Biology and Computational Proteomics

Systems Biology and Computational Proteomics
Author: Trey Ideker
Publisher: Springer
Total Pages: 138
Release: 2007-09-19
Genre: Science
ISBN: 3540730605

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This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.


Genomics and Proteomics

Genomics and Proteomics
Author: Sándor Suhai
Publisher: Springer Science & Business Media
Total Pages: 246
Release: 2000-07-31
Genre: Medical
ISBN: 0306463121

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Proceedings of an International Conference on Genomics and Proteomics: Functional and Computational Aspects, held October 4-7, 1998, in Heidelberg, Germany


Bioinformatics and the Cell

Bioinformatics and the Cell
Author: Xuhua Xia
Publisher: Springer Science & Business Media
Total Pages: 376
Release: 2007-05-08
Genre: Science
ISBN:

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Biological and biomedical sciences are becoming more interdisciplinary, and scientists of the future need inte rdisciplinary training instead of the conventional disciplinary training. Just as Sean Eddy (2005) wiselypointed out that sending monolingual diplomats to the United Nations maynot enhance international collaborations, combining strictly disciplinary scientists trained in either mathematics, computational science or molecular biology will not create a productive inte rdisciplinary team ready to solve interdisciplinary problems. Molecular biology is an interdiscip linary science back in its heyday, and founders of molecular biology were ofte n interdisciplinary scientists. Indeed, Francis Crick considered himself as “a mixture of crystallographer, biophysicist, biochemist, and geneticist” (Crick, 1965). Because it was too cumbersome to explain to people that he was such a mixture, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist, and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in each other’s problems.


Bioinformatics of Human Proteomics

Bioinformatics of Human Proteomics
Author: Xiangdong Wang
Publisher: Springer Science & Business Media
Total Pages: 396
Release: 2013-01-26
Genre: Science
ISBN: 9400758111

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“Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction network, drug discovery and development, the relationship between translational medicine and bioinformatics, and advances in proteomic methods, while also demonstrating important bioinformatics tools and methods available today for protein analysis, interpretation and predication. It is intended for experts or senior researchers in the fields of clinical research-related biostatistics, bioinformatics, computational biology, medicine, statistics, system biology, molecular diagnostics, biomarkers, or drug discovery and development. Dr.Xiangdong Wang works as a distinguished professor of Respiratory Medicine at Fudan University, Shanghai, China. He serves as Director of Biomedical Research Center, Fudan University Zhongshan Hospital and adjunct professor of Clinical Bioinformatics at Lund University, Sweden. His main research is focused on the role of clinical bioinformatics in the development of disease-specific biomarkers and dynamic network biomarkers, the molecular mechanism of organ dysfunction and potential therapies.


Bioinformatics and the Cell

Bioinformatics and the Cell
Author: Xuhua Xia
Publisher: Springer Science & Business Media
Total Pages: 363
Release: 2007-04-24
Genre: Science
ISBN: 0387713379

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The many books that have been published on bioinformatics tend toward either of two extremes: those that feature computational details with a great deal of mathematics, for computational scientists and mathematicians; and those that treat bioinformatics as a giant black box, for biologists. This is the first book using comprehensive numerical illustration of mathematical techniques and computational algorithms used in bioinformatics that converts molecular data into organized biological knowledge.