Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Comprehensive Assessment Of Uncertainties And Errors In 18fnaf Pet Imaging PDF full book. Access full book title Comprehensive Assessment Of Uncertainties And Errors In 18fnaf Pet Imaging.
| Author | : Ngoneh Jallow |
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| Total Pages | : |
| Release | : 2014 |
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| Author | : |
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| Total Pages | : 0 |
| Release | : 2014 |
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Quantitative PET imaging is increasingly being used as a tool for treatment response assessment of various types of cancers, supplementing the conventional qualitative anatomical imaging. [18F]NaF is a radiotracer used for imaging of metastatic bone lesions and provides a means of visualizing and quantifying metabolic activity. [18F]NaF PET images provide better sensitivity and quantitative response assessment of the bone lesions compared to the 99mTc which is currently the clinical standard. Nevertheless, for accurate and reliable use of [18F]NaF PET for response assessment of metastatic bone lesions, many factors need to be thoroughly understood. These include the understanding of the uncertainties and errors associated with quantitative [18F]NaF PET imaging and how these uncertainties and errors impact treatment response assessment. Additionally, the reproducibility of [18F]NaF PET imaging metrics need to be assessed to determine their value as quantitative biomarkers for response assessment. This thesis work comprehensively characterized the uncertainties and errors in quantitative [18F]NaF PET imaging and investigated the impact of these uncertainties and errors on absolute and relative quantitative PET measures used in treatment response assessment. The lesions within the patients were evaluated globally and individually to understand both inter-patient and intra-patient variations. Additionally, the reproducibility of [18F]NaF PET imaging metrics such as SUV and textural features was evaluated. All these studies were performed on a multi-center clinical trial data set that used [18F]NaF PET/CT to assess treatment efficacy of metastatic bone lesions. We found that [18F]NaF PET imaging is highly reproducible; however it is affected by many uncertainties which translate to uncertainties and errors in response assessment and these need to be taken into consideration in clinical practice. We also developed and tested a methodology to quantitatively harmonize the data from the different PET/CT scanners used in the trial to increase accuracy of [18F]NaF PET/CT data. The methodology included both phantom-based and patient-based harmonization of the PET data.
| Author | : R. Lor Randall |
| Publisher | : Springer |
| Total Pages | : 356 |
| Release | : 2015-12-01 |
| Genre | : Medical |
| ISBN | : 1461456622 |
Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.
| Author | : Simon R. Cherry |
| Publisher | : |
| Total Pages | : 552 |
| Release | : 2003 |
| Genre | : Medical |
| ISBN | : |
In this work, the authors provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labelled tracers. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.
| Author | : Khalil Fattouch |
| Publisher | : Springer |
| Total Pages | : 418 |
| Release | : 2018-04-03 |
| Genre | : Medical |
| ISBN | : 3319664832 |
This book describes the different aspects of aortic valve and root diseases including comprehensive discussion of the state-of-the-art diagnostic imaging options, disease risk stratification, selection of candidates for valve repair or percutaneous intervention, and most recent therapeutic options. The growing prevalence of valvular heart disease represents a major challenge in terms of short- and long-term management and surveillance. Aortic valve diseases, including aortic stenosis and regurgitation, are among the most frequent of these, while the number of cases of aortic root disease is also on the rise. Aortic valve disease treatment options include valve surgery, valve repair, minimally invasive valve surgery, and percutaneous approaches and all are covered in this volume. Advances in Treatments for Aortic Valve and Root Diseases is a highly illustrated, case oriented reference aimed at cardiology fellows in training, while also helpful to surgeons, cardiologists, imagers, interventionalists, as well as other clinicians and students involved in the diagnosis and treatment of aortic valve and root diseases.
| Author | : Francesco Sardanelli |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 244 |
| Release | : 2009-03-31 |
| Genre | : Medical |
| ISBN | : 8847011337 |
The aim of this book is to present statistical problems and methods in a friendly way to radiologists, emphasizing statistical issues and methods most frequently used in radiological studies (e.g., nonparametric tests, analysis of intra- and interobserver reproducibility, comparison of sensitivity and specificity among different imaging modality, difference between clinical and screening application of diagnostic tests, ect.). The tests will be presented starting from a radiological "problem" and all examples of statistical methods applications will be "radiological".
| Author | : Tomaž Vrtovec |
| Publisher | : Springer |
| Total Pages | : 167 |
| Release | : 2016-07-20 |
| Genre | : Computers |
| ISBN | : 3319418270 |
This book constitutes the refereed proceedings of the Third International Workshop and Challenge on Computational Methods and Clinical Applications for Spine Imaging, CSI 2015, held in conjunction with MICCAI 2015, in Munich, Germany, in October 2015. The 9 workshop papers and 6 challenge contributions were carefully reviewed and selected for inclusion in this volume. The papers cover all major aspects related to spine imaging.
| Author | : Jean J. M. C. H. Rosette |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 427 |
| Release | : 2008-11-23 |
| Genre | : Medical |
| ISBN | : 1846287596 |
A hugely important book that details significant changes in imaging in oncological conditions related to the bladder, prostate and kidneys. The sole focus is on oncology in urology, mainly Ultrasound and MRI, with organ-oriented topics. The latest technologies on imaging are included to better identify carcinomatous lesions and lymph node metastases. Each chapter includes a section that outlines the optimal imaging approach, providing an algorithm for imaging per disease entity, and according to the evidence-based chronological and diagnostic follow-up.
| Author | : Andrei Iagaru |
| Publisher | : Springer |
| Total Pages | : 435 |
| Release | : 2018-01-23 |
| Genre | : Medical |
| ISBN | : 3319685171 |
In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists in nuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.
| Author | : Stephen W. Leslie |
| Publisher | : McGraw Hill Professional |
| Total Pages | : 688 |
| Release | : 2013-06-22 |
| Genre | : Medical |
| ISBN | : 0071799273 |
4,000 quick-hit Q&As and over 100 X-ray and ultrasound images help you ace the Urology boards Like flashcards in a book, this quick-hit question and answer review for the urology boards provides intense, streamlined review and is the perfect complement to larger urology and surgery texts. You'll find more than 3,300 Q&As with only the right answer provided - there are no multiple-choice distracters - so there's no chance of an incorrect answer staying in your mind. Also included are more than 100 X-rays and ultrasound images. Chapters are written by experts in the field to give you comprehensive coverage of important urological topics. Presented in a rigorous quick-hit question and answer style consisting of short clinical questions with concise answers Emphasis on distilling key facts and clinical pearls that are essential for exam success Questions on new technologies such as robotics and laparoscopic surgery, advances in cancer chemotherapy, medical urology, and complications related to new medicines (such as Topamax) High-quality of x-rays and imaging study pictures, including many new images (more then 100 in all)
