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Collective Behavior In Systems Biology

Collective Behavior In Systems Biology
Author: Assaf Steinschneider
Publisher: Academic Press
Total Pages: 260
Release: 2019-09-04
Genre: Science
ISBN: 0128173378

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Collective Behavior In Systems Biology: A Primer on Modeling Infrastructure offers a survey of established and emerging methods for quantifying process behavior in cellular systems. It introduces and applies mathematics and related abstract methods to processes in biological systems - why they are used, how they work, and what they mean. Emphasizing differential equations in an interdisciplinary approach, this book discusses infrastructure for kinetic modeling, technological system and control theories, optimization, and process behavior in cellular networks. The knowledge that the reader gains will be valuable for entering and keeping up with a rapidly developing discipline. Introduces basics of mathematical and abstract methods for understanding, predicting, and modifying collective behavior in cellular systems Targets biomedical professionals as well as computational specialists who are willing to take advantage of novel high-throughput data acquisition technologies


The Ecology of Collective Behavior

The Ecology of Collective Behavior
Author: Deborah M. Gordon
Publisher: Princeton University Press
Total Pages: 184
Release: 2023-10-24
Genre: Science
ISBN: 0691232164

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A groundbreaking new perspective on collective behavior across biological systems Collective behavior is everywhere in nature, from gene transcription and cancer cells to ant colonies and human societies. It operates without central control, using local interactions among participants to allow groups to adjust to changing conditions. The Ecology of Collective Behavior brings together ideas from evolutionary biology, network science, and dynamical systems to present an ecological approach to understanding how the interactions of individuals generate collective outcomes. Deborah Gordon argues that the starting point for explaining how collective behavior works in any natural system is to consider how it changes in relation to the changing world around it. She shows how feedback use—the means by which networks of interactions operate—and the organization of interaction networks evolve to reflect the stability and demands of the environment. Ant colonies function collectively, and the enormous diversity of species in different habitats provides opportunities to look for general ecological patterns. Through an in-depth comparison of ant species, Gordon identifies broad trends in how the diversity of collective behavior in many other collective systems reflects the dynamics of the environment. Shedding light on how individual actions give rise to group behavior, The Ecology of Collective Behavior explains the evolution of collective behavior through innovation in participant interactions, offering new insights into how collective responses function in changing conditions.


Dynamics and Analysis of Alignment Models of Collective Behavior

Dynamics and Analysis of Alignment Models of Collective Behavior
Author: Roman Shvydkoy
Publisher: Springer Nature
Total Pages: 208
Release: 2021-05-13
Genre: Mathematics
ISBN: 3030681475

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This book introduces a class of alignment models based on the so-called Cucker-Smale system as well as its kinetic and hydrodynamic counterparts. Cutting edge research in the area of collective behavior is presented, including emerging techniques from fluid mechanics, fractional analysis, and kinetic theory. Analytical aspects are highlighted throughout, such as regularity theory and long time behavior of solutions. Featuring open problems, readers will be motivated to apply these breakthrough methods to future research. The chapters offer an overview of state of the art research with introductions to core concepts. Chapter One introduces the central focus of the book: The agent-based Cucker-Smale system. Further agent-based systems and alignment systems are covered in chapters Two and Three. Following this are chapters covering the kinetic and hydrodynamic variants of the Cucker-Smale system. The core well-posedness theory of both smooth and singular models is then presented. Chapter Eight discusses the fully developed one-dimensional theory. The final chapter presents some of the known partial results concerning the regularity of multidimensional Euler Alignment systems. Dynamics and Analysis of Alignment Models of Collective Behavior is ideal for graduate students and researchers studying PDEs, especially those interested in the active areas of collective behavior and alignment models.


Control Theory and Systems Biology

Control Theory and Systems Biology
Author: Pablo A. Iglesias
Publisher: MIT Press
Total Pages: 359
Release: 2010
Genre: Biological control systems
ISBN: 0262013347

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A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.


Collective Behavior

Collective Behavior
Author: The National Academies Keck Futures Initiative
Publisher: National Academies Press
Total Pages: 194
Release: 2015-06-25
Genre: Science
ISBN: 0309373506

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Collective Behavior is the summary of the 2014 National Academies Keck Futures Initiative Conference on Collective Behavior. Participants were divided into fourteen interdisciplinary research teams. The teams spent nine hours over two days exploring diverse challenges at the interface of science, engineering, and medicine. The composition of the teams was intentionally diverse, to encourage the generation of new approaches by combining a range of different types of contributions. The teams included researchers from science, engineering, and medicine, as well as representatives from private and public funding agencies, universities, businesses, journals, and the science media. Researchers represented a wide range of experience - from postdoc to those well established in their careers - from a variety of disciplines that included science and engineering, medicine, physics, biology, economics, and behavioral science. The teams needed to address the challenge of communicating and working together from a diversity of expertise and perspectives as they attempted to solve a complicated, interdisciplinary problem in a relatively short time. This report highlights the presentations of the event and includes the team reports and pre-meeting materials.


Computational Methods in Systems Biology

Computational Methods in Systems Biology
Author: Alessandro Abate
Publisher: Springer Nature
Total Pages: 387
Release: 2020-10-01
Genre: Computers
ISBN: 303060327X

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This book constitutes the refereed proceedings of the 18th International Conference on Computational Methods in Systems Biology, CMSB 2020, held in Konstanz, Germany, in September 2020.* The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology. * The conference was held virtually due to the COVID-19 pandemic.


The Ecology of Collective Behavior

The Ecology of Collective Behavior
Author: Deborah M. Gordon
Publisher: Princeton University Press
Total Pages: 184
Release: 2023-10-24
Genre: Science
ISBN: 0691232148

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A groundbreaking new perspective on collective behavior across biological systems Collective behavior is everywhere in nature, from gene transcription and cancer cells to ant colonies and human societies. It operates without central control, using local interactions among participants to allow groups to adjust to changing conditions. The Ecology of Collective Behavior brings together ideas from evolutionary biology, network science, and dynamical systems to present an ecological approach to understanding how the interactions of individuals generate collective outcomes. Deborah Gordon argues that the starting point for explaining how collective behavior works in any natural system is to consider how it changes in relation to the changing world around it. She shows how feedback use—the means by which networks of interactions operate—and the organization of interaction networks evolve to reflect the stability and demands of the environment. Ant colonies function collectively, and the enormous diversity of species in different habitats provides opportunities to look for general ecological patterns. Through an in-depth comparison of ant species, Gordon identifies broad trends in how the diversity of collective behavior in many other collective systems reflects the dynamics of the environment. Shedding light on how individual actions give rise to group behavior, The Ecology of Collective Behavior explains the evolution of collective behavior through innovation in participant interactions, offering new insights into how collective responses function in changing conditions.


Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences

Mathematical Modeling of Collective Behavior in Socio-Economic and Life Sciences
Author: Giovanni Naldi
Publisher: Springer Science & Business Media
Total Pages: 437
Release: 2010-08-12
Genre: Mathematics
ISBN: 0817649468

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Using examples from finance and modern warfare to the flocking of birds and the swarming of bacteria, the collected research in this volume demonstrates the common methodological approaches and tools for modeling and simulating collective behavior. The topics presented point toward new and challenging frontiers of applied mathematics, making the volume a useful reference text for applied mathematicians, physicists, biologists, and economists involved in the modeling of socio-economic systems.