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| Author | : Great Britain. Home Office |
| Publisher | : |
| Total Pages | : 212 |
| Release | : 2014 |
| Genre | : Animal experimentation |
| ISBN | : 9781474112390 |
| Author | : Great Britain. Home Office |
| Publisher | : |
| Total Pages | : 212 |
| Release | : 2014 |
| Genre | : Animal experimentation |
| ISBN | : 9781474112406 |
| Author | : Huw Golledge |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1044 |
| Release | : 2024-03-12 |
| Genre | : Medical |
| ISBN | : 1119555280 |
The UFAW Handbook on The Care and Management of Laboratory and Other Research Animals The latest edition of the seminal reference on the care and management of laboratory and research animals The newly revised ninth edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date and authoritative exploration on worldwide developments, current thinking, and best practices in the field of laboratory animal welfare science and technology. The gold standard in laboratory and captive animal care and management references, this latest edition continues the series’ tradition of excellence by including brand-new chapters on ethical review, the care of aged animals, and fresh guidance on the care of mole rats, corvids, zebrafish, and decapods. The book offers introductory chapters covering a variety of areas of laboratory animal use, as well as chapters on the management and care of over 30 different taxa of animals commonly utilised in scientific procedures and research around the world. It also provides: A thorough introduction to the design of animal experiments, laboratory animal genetics, and the phenotyping of genetically modified mice Comprehensive explorations of animal welfare assessment and the ethical review process Practical discussions of legislation and oversight of the conduct of research using animals from a global perspective In-depth examinations of the planning, design, and construction of efficient animal facilities, special housing arrangements, and nutrition, feeding, and animal welfare The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals Ninth Edition is essential for laboratory animal scientists, veterinarians, animal care staff, animal care regulatory authorities, legislators, and professionals working in animal welfare non-governmental organizations.
| Author | : Robert H. Weichbrod |
| Publisher | : CRC Press |
| Total Pages | : 1405 |
| Release | : 2017-09-07 |
| Genre | : Medical |
| ISBN | : 1351648225 |
AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).
| Author | : Catherine Duxbury |
| Publisher | : Routledge |
| Total Pages | : 224 |
| Release | : 2021-09-30 |
| Genre | : Social Science |
| ISBN | : 0429867336 |
This book offers an historical analysis of the culture of animal-dependent science in Britain from 1945 to the present, exploring key areas of animal experimentation such as warfare, medical science and law from a gendered perspective. Questioning the nature of knowledge production in this area, and how animal experimentation intersects with broader cultural norms and values concerning sex, and gender, it examines the impact of contemporary forms of capitalism on animal dependent science, its historical trajectory and gendered configuration. With close attention to the broad social context from the creation of the Welfare State and the loss of Empire, to the emergence of neoliberalism in the 1980s and its present day omnipotent manifestation, the author asks how animal experimentation and the use of nonhuman animals in specific areas of science is gendered and has implications for women. Drawing on a variety of sociological, philosophical, feminist and historical theories and engaging with a wealth of primary and secondary materials of scientific research of the time, Science, Gender and the Exploitation of Animals in Britain Since 1945 contends that there is a persistent, gendered ideology of animal use which remains inscribed within the policies of the British neoliberal state. As such, it will appeal to scholars of sociology, history and philosophy with interests in gender and the treatment of nonhuman animals.
| Author | : Suzie Hingley-Wilson |
| Publisher | : Frontiers Media SA |
| Total Pages | : 297 |
| Release | : 2023-12-28 |
| Genre | : Medical |
| ISBN | : 2832519164 |
The macrophage (or “big eater”) is often considered the first cell type to encounter the causative agent of Tuberculosis (TB), Mycobacterium tuberculosis, upon entry to the lung. Once inside the macrophage the tubercle bacillus can survive and even replicate where many other invading pathogens perish. Recent research suggests the bacilli adapts within this hostile environment, treating the macrophage like a Trojan horse. Indeed, cutting-edge techniques have revealed that the degree of bacterial heterogeneity and resistance to antibiotics changes within the macrophage. M. tuberculosis spends most of its life cycle within the macrophage and has adopted specific mechanisms to survive, egress and to recruit more of this niche cell (eg the Type VII secretion system ESX-1). Understanding the host-pathogen interaction in tuberculous infection is key to understanding TB, which remains the number one cause of death from a bacterial infection. In this research topic we aim to cover advances in understanding how the tubercle bacillus adapts and survives within the host cell. Determining the responsible mechanisms may reveal novel ways to target this deadly pathogen and halt its adaptation and transformation within these potentially destructive or permissive cells.
| Author | : Ray Tricker |
| Publisher | : Taylor & Francis |
| Total Pages | : 1163 |
| Release | : 2022-05-30 |
| Genre | : Architecture |
| ISBN | : 1000572234 |
This tenth edition of the most popular and trusted guide reflects all the latest amendments to the Building Regulations, planning permission and the Approved Documents in England and Wales. This includes coverage of the recent changes to use classes, updated sections on planning permission, permitted development and application fees. We have included the revisions to Approved Document B (as a result of the Hackitt Review), as well as the latest changes to Approved Documents F and L, and the new documents O (overheating) and S (electric vehicle charging points), which come into effect in June 2022. Giving practical information throughout on how to work with (and within) the Regulations, this book enables compliance in the simplest and most cost-effective manner possible. The no-nonsense approach of Building Regulations in Brief cuts through any confusion and explains the meaning of the Regulations. Consequently, it has become a favourite for anyone working in or studying the building industry, as well as those planning to have work carried out on their home. It is essential reading for all building contractors and subcontractors, site engineers, building engineers, building control officers, building surveyors, architects, construction site managers and DIYers.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 161 |
| Release | : 2015-12-04 |
| Genre | : Science |
| ISBN | : 030937927X |
In order to better understand the critical issues pertaining to the concept of performance standards for laboratory animal use, the Institute for Laboratory Animal Research Roundtable on Science and Welfare in Laboratory Animal Use held a public workshop on April 20-21, 2015. The purpose of the workshop was to promote the appropriate and responsible care of animals in research, to provide a balanced and civil forum for discussion and collaboration, and to help build transparency and trust among stakeholders. Participants addressed the challenges of defining, developing, implementing, assessing, and validating performance standards to ensure "optimal practices, management, and operations." This report summarizes the presentations and discussions from the workshop.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 246 |
| Release | : 2011-01-27 |
| Genre | : Science |
| ISBN | : 0309154006 |
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.
| Author | : Robert P. Marini |
| Publisher | : Academic Press |
| Total Pages | : 572 |
| Release | : 2018-11-19 |
| Genre | : Science |
| ISBN | : 012811830X |
The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications Includes contributions from renowned and international authors and editors Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series
