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Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain
Author: George F. Koob
Publisher: Academic Press
Total Pages: 351
Release: 2014-07-12
Genre: Medical
ISBN: 0123869595

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Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction


Cocaine and a Changing Brain

Cocaine and a Changing Brain
Author: National Institute on Drug Abuse. Division of Basic Research
Publisher:
Total Pages: 41
Release: 1999
Genre: Brain
ISBN:

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False Messengers

False Messengers
Author: David P. Friedman
Publisher: CRC Press
Total Pages: 214
Release: 2003-09-02
Genre: Science
ISBN: 0203304977

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This book provides a scientific explanation of drug abuse and addiction for the general public. It clarifies the meaning of concepts such as intoxication, physical dependence, and addiction, and describes the changes in the brain that underlie these states. Indeed, this volume is unique because it presents a comprehensive picture of what actually happens to people and their brains when they chronically self-administer opiates, stimulants or alcohol. Complex mechanisms of drug action in the brain are made simple and comprehensible to the layman through use of informative analogies and salient graphics. Accounts of the effects of drug use and abuse on normal people create meaningful, easy-to-relate-to examples from everyday life.


Never Enough

Never Enough
Author: Judith Grisel
Publisher: Anchor
Total Pages: 257
Release: 2020-01-14
Genre: Psychology
ISBN: 0525434909

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NEW YORK TIMES BESTSELLER • From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.


The Neuroscience of Cocaine

The Neuroscience of Cocaine
Author: Victor R Preedy
Publisher: Academic Press
Total Pages: 776
Release: 2017-05-23
Genre: Psychology
ISBN: 012803792X

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The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Illustrated in full color Provides unique full coverage of all aspects of cocaine and its related pathology Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms


Cocaine in the Brain

Cocaine in the Brain
Author: Nora D. Volkow
Publisher:
Total Pages: 218
Release: 1990
Genre: Medical
ISBN:

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Abstract: In discussing the consequences of cocaine use on individuals and society, this volume presents up-to-date research on brain mechanisms of cocaine use including the historical/social and psychological perspectives. The publication assists readers in comprehending the cocaine problem from multiple perspectives, beginning with the neural mechanisms of craving and leading to new approaches to developing effective diagnostic, treatment, and prevention programs. Topics include: populations at risk for cocaine use and subsequent consequences, synaptic effects and adaptations of cocaine, imaging techniques in the investigation of the effects of cocaine in the brain, and medical, endocrinological, and pharmacological aspects of cocaine addiction.


The Addicted Brain

The Addicted Brain
Author: Michael J. Kuhar
Publisher: FT Press
Total Pages: 237
Release: 2012
Genre: Family & Relationships
ISBN: 0132542501

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"The Addicted Brain" explains clearly and vividly what has been learned about how and why some people become addicted and abuse drugs or other substances, the relatively long-term changes these substances can make in the brain, and the progress being made on treatments.