Clinical Trials In Neurologic Practice PDF Download
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Author | : José Biller |
Publisher | : Butterworth-Heinemann |
Total Pages | : 378 |
Release | : 2001 |
Genre | : Medical |
ISBN | : |
Download Clinical Trials in Neurologic Practice Book in PDF, ePub and Kindle
This text covers the neurologic areas where trials have become increasingly important, including stroke, epilepsy, head and spinal cord injuries, and movement disorders. By applying the clinical evidence gained from the trials to neurologic practice, clinicians will be better positioned to meet the needs of their patients. * A practical approach to assist neurologists and neurologists in training in the understanding of clinical trials for neurologic disorders * Authors have assembled a distinguished international group of contributors to critically evaluate trials that have been conducted in their areas of expertise * Ideal book for practitioners interested in evidence-based neurologic practice
Author | : Bernard Ravina |
Publisher | : Cambridge University Press |
Total Pages | : 387 |
Release | : 2012-04-12 |
Genre | : Medical |
ISBN | : 1107376572 |
Download Clinical Trials in Neurology Book in PDF, ePub and Kindle
Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.
Author | : Roberto J. Guiloff |
Publisher | : Springer Science & Business Media |
Total Pages | : 537 |
Release | : 2013-03-14 |
Genre | : Medical |
ISBN | : 1447137876 |
Download Clinical Trials in Neurology Book in PDF, ePub and Kindle
Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
Author | : E. Beghi |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 168 |
Release | : 2016-07-26 |
Genre | : Medical |
ISBN | : 3318058653 |
Download The Right Therapy for Neurological Disorders Book in PDF, ePub and Kindle
Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.
Author | : David Y. Hwang |
Publisher | : Oxford University Press |
Total Pages | : 378 |
Release | : 2016 |
Genre | : Medical |
ISBN | : 0199377529 |
Download 50 Studies Every Neurologist Should Know Book in PDF, ePub and Kindle
'50 Studies Every Neurologist Should Know' presents summaries and analyses of clinical trials that have shaped the current practice of neurology. Every subspecialty is covered, with special emphasis on neurocritical care and vascular neurology.
Author | : Kate T. Brizzi |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 252 |
Release | : 2017-07-12 |
Genre | : Medical |
ISBN | : 1496348958 |
Download Neurology Evidence Book in PDF, ePub and Kindle
Synthesizing the vast body of literature available in neurology into one accessible, clinically relevant volume, Neurology Evidence: The Practice-Changing Studies is an invaluable resource for students, residents, and fellows, as well as neurologists at all levels of experience. Featuring the top 100 papers that have had the most significant impact on changing clinical practice, this unique title analyzes the strengths and weaknesses of both seminal and less-noticed studies. Readable commentary is provided for each study by both a senior and junior neurologist in each subspecialty.
Author | : National Academies of Sciences, Engineering, and Medicine |
Publisher | : National Academies Press |
Total Pages | : 111 |
Release | : 2016-11-07 |
Genre | : Medical |
ISBN | : 0309442583 |
Download Neuroscience Trials of the Future Book in PDF, ePub and Kindle
On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.
Author | : Katherine M. Woodbury-Harris |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 225 |
Release | : 2009 |
Genre | : Medical |
ISBN | : 3805590237 |
Download Clinical Trials in the Neurosciences Book in PDF, ePub and Kindle
A properly designed and executed clinical trial that addresses an import question and delivers a definitive result can change the practice of medicine worldwide. This book encompasses a bench-to-bedside approach and serves as an excellent guidance for translating preclinical studies to early phase I/II and phase III trials. In the first part, the book covers preclinical science with respect to animal models of various neurological diseases, FDA requirements for preclinical studies, translation of animal to patient studies and scaling up from animal to human studies. In the second part, the design of phase I/II trials and the use of biomarkers as surrogate endpoints are discussed. With regard to phase III trials, FDA and European requirements, specific design issues, relevant clinical endpoints as well as data management and quality are examined. Topics specific to multicenter trials, such as design, recruitment of special populations, monitoring, ethical and consent issues are also covered. Finally, genetics, gene therapy, imaging and surgical devices are reviewed.This publication is highly recommended to clinician researchers, such as neurologists, neurosurgeons, pediatric neurologists and neonatologists, who want to design and conduct clinical trials in the neuroscience, but also to nurses, research coordinators and clinical pharmacologists.
Author | : Lorene M. Nelson |
Publisher | : Oxford University Press |
Total Pages | : 480 |
Release | : 2004 |
Genre | : Medical |
ISBN | : 019513379X |
Download Neuroepidemiology Book in PDF, ePub and Kindle
This fine text provides a comprehensive overview of methods for epidemiologic and clinical research on neurological disorders. The book focuses on classic principles of study design in epidemiologic research, strategies for avoiding study biases, methods for conducting clinical trials and prognostic studies, and principles of evidence-based medicine in neurology. The text gives neurologists, epidemiologists, and their students the foundation for conducting rigorous epidemiologic and clinical research on neurologic disorders.
Author | : Martin A. Samuels |
Publisher | : |
Total Pages | : 1326 |
Release | : 1996 |
Genre | : Medical |
ISBN | : |
Download Office Practice of Neurology Book in PDF, ePub and Kindle
A multidisciplinary team offers a definitive and practical source on nervous system dysfunction as it relates to ambulatory patients, and provide concise diagnosis and treatment recommendations.