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The Great Ideas of Clinical Science

The Great Ideas of Clinical Science
Author: Scott O. Lilienfeld
Publisher: Routledge
Total Pages: 478
Release: 2012-12-06
Genre: Psychology
ISBN: 1135930171
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The idea that there is a fundamental rift between researchers and practitioners should not come as a surprise to anyone familiar with the current literature, trends, and general feelings in the field of clinical psychology. Central to this scientist-practitioner gap is an underlying disagreement over the nature of knowledge - namely that while some individuals point to research studies as the foundation of truth, others argue that clinical experience offers a more adequate understanding of the causes, assessment, and treatment of mental illness. The Great Ideas of Clinical Science is an ambitious attempt to dig beneath these fundamental differences, and reintroduce the reader to unifying principles often overlooked by students and professionals alike. The editors have identified 17 such universals, and have pulled together a group of the most prolific minds in the field to present the philosophical, methodological, and conceptual ideas that define the state of the field. Each chapter focuses on practical as well as conceptual points, offering valuable insight to practicing clinicians, researchers, and teachers of any level of experience. Written for student, practitioner, researcher, and educated layperson, this integrative volume aims to facilitate communication among all mental health professionals and to narrow the scientist-practitioner gap.

Clinical and Translational Science

Clinical and Translational Science
Author: David Robertson
Publisher: Academic Press
Total Pages: 812
Release: 2016-11-25
Genre: Science
ISBN: 012802111X
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Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Fundamentals of Clinical Data Science

Fundamentals of Clinical Data Science
Author: Pieter Kubben
Publisher: Springer
Total Pages: 219
Release: 2018-12-21
Genre: Medical
ISBN: 3319997130
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This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.

Basic Science Methods for Clinical Researchers

Basic Science Methods for Clinical Researchers
Author: Morteza Jalali
Publisher: Academic Press
Total Pages: 383
Release: 2017-03-31
Genre: Science
ISBN: 012803078X
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Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Understanding Clinical Research

Understanding Clinical Research
Author: Renato D. Lopes
Publisher: McGraw Hill Professional
Total Pages: 262
Release: 2013-05-22
Genre: Medical
ISBN: 0071792651
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A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

Advancing the Nation's Health Needs

Advancing the Nation's Health Needs
Author: National Research Council
Publisher: National Academies Press
Total Pages: 187
Release: 2005-08-13
Genre: Medical
ISBN: 0309094275
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This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.

Designing Clinical Research

Designing Clinical Research
Author: Stephen B. Hulley
Publisher: Lippincott Williams & Wilkins
Total Pages: 388
Release: 2011-11-30
Genre: Medical
ISBN: 1451165854
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Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research
Author: John I. Gallin
Publisher: Elsevier
Total Pages: 447
Release: 2011-04-28
Genre: Science
ISBN: 0080489567
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The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Health Care Delivery and Clinical Science

Health Care Delivery and Clinical Science
Author: Information Resources Management Association
Publisher:
Total Pages: 0
Release: 2018
Genre: Health literacy
ISBN: 9781522539261
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The development of better processes to provide proper healthcare has enhanced contemporary society. By implementing effective collaborative strategies, this ensures proper quality and instruction for both the patient and medical practitioners. Health Care Delivery and Clinical Science: Concepts, Methodologies, Tools, and Applications is a comprehensive reference source for the latest scholarly material on emerging strategies and methods for delivering optimal healthcare and examines the latest techniques and methods of clinical science. Highlighting a range of pertinent topics such as medication management, health literacy, and patient engagement, this multi-volume book is ideally designed for professionals, practitioners, researchers, academics, and graduate students interested in healthcare delivery and clinical science.

The Great Ideas of Clinical Science

The Great Ideas of Clinical Science
Author: Scott O. Lilienfeld
Publisher: Taylor & Francis
Total Pages: 447
Release: 2012-12-06
Genre: Psychology
ISBN: 113593018X
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Download The Great Ideas of Clinical Science Book in PDF, ePub and Kindle

The idea that there is a fundamental rift between researchers and practitioners should not come as a surprise to anyone familiar with the current literature, trends, and general feelings in the field of clinical psychology. Central to this scientist-practitioner gap is an underlying disagreement over the nature of knowledge - namely that while some individuals point to research studies as the foundation of truth, others argue that clinical experience offers a more adequate understanding of the causes, assessment, and treatment of mental illness. The Great Ideas of Clinical Science is an ambitious attempt to dig beneath these fundamental differences, and reintroduce the reader to unifying principles often overlooked by students and professionals alike. The editors have identified 17 such universals, and have pulled together a group of the most prolific minds in the field to present the philosophical, methodological, and conceptual ideas that define the state of the field. Each chapter focuses on practical as well as conceptual points, offering valuable insight to practicing clinicians, researchers, and teachers of any level of experience. Written for student, practitioner, researcher, and educated layperson, this integrative volume aims to facilitate communication among all mental health professionals and to narrow the scientist-practitioner gap.