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Clinical Research Methods for Surgeons

Clinical Research Methods for Surgeons
Author: David F. Penson
Publisher: Springer Science & Business Media
Total Pages: 338
Release: 2007-11-06
Genre: Medical
ISBN: 1597452300

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With his keen analytical mind and penchant for organization, Charles Darwin would have made an excellent clinical investigator. Unfortunately for surgery, his early exposure at Edinburgh to the brutality of operations in 1825 convinced him to reject his father’s plan for his career and pursue his interest in nature. His subsequent observations of how environmental pressures shaped the development of new species provided the essential mechanism to explain evolution and the disappearance of those species that failed to adapt. Today, surgeons face the same reality as new technology, progressive regulation by government and payers, medico-legal risks, and public demands for proof of performance force changes in behavior that our predecessors never imagined. We know that surgeons have always prided themselves on accurate documentation of their results, including their complications and deaths, but observational studies involving a single surgeon or institution have given way to demands for controlled interventional trials despite the inherent difficulty of studying surgical patients by randomized, blinded techniques. That is why this book is so timely and important. In a logical and comprehensive approach, the authors have assembled a group of experienced clinical scientists who can demonstrate the rich variety of techniques in epidemiology and statistics for reviewing existing publications, structuring a clinical study, and analyzing the resulting data.


Clinical Research for Surgeons

Clinical Research for Surgeons
Author: Mohit Bhandari
Publisher: Thieme
Total Pages: 334
Release: 2011-01-01
Genre: Medical
ISBN: 3131494514

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Praise for this book:Readable, relevant, and interesting...this book cuts through jargon, recapitulates key concepts, and clarifies with current examples from the literature...recommend[ed].--Doody's ReviewClinical Research for Surgeons is a practical guide for understanding, planning, conducting, and evaluating surgical research. It covers the principles of evidence-based surgery and applies these principles to the design of suitable research studies. The reader will come to fully understand important concepts such as case-control study, prospective cohort study, randomized trial, and reliability study. The book provides valuable discussions of the critical appraisal of published clinical studies, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care.Highlights: Insights from experienced surgeons and veteran researchers Easy-to-reference text boxes with Key Concepts, Jargon Simplified, and Examples from the Literature Coverage of both open and minimally-invasive surgical procedures 50 illustrations demonstrating key points This book is a valuable reference for clinicians and residents in a range of disciplines, including general surgery, orthopedic surgery, plastic and reconstructive surgery, urology, neurosurgery, otolaryngology-head and neck surgery, interventional radiology, cardiac surgery.


Surgical Research

Surgical Research
Author: Wiley W. Souba
Publisher: Academic Press
Total Pages: 1526
Release: 2001-01-25
Genre: Health & Fitness
ISBN: 9780126553307

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Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...


Clinical Trials

Clinical Trials
Author: Timothy M. Pawlik
Publisher: Springer Nature
Total Pages: 254
Release: 2020-03-10
Genre: Medical
ISBN: 3030354881

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This extensively revised second edition is a unique and portable handbook focusing on clinical trials in surgery. It includes new educational materials addressing the rapid evolution of novel research methodologies in basic science, clinical and educational research. The underlying principles of clinical trials, trial design, the development of a study cohort, statistics, data safety, data monitoring, and trial publication for device and drug trials are also discussed. Clinical Trials provides a comprehensive resource on clinical trials in surgery and describes all the stages of a clinical trial from generating a hypothesis through to trial publication and is a valuable resource for all practicing and trainee academic surgeons.


Clinical Research for Surgeons

Clinical Research for Surgeons
Author: Mohit Bhandari
Publisher: Thieme
Total Pages: 334
Release: 2008-12-17
Genre: Medical
ISBN: 3132579262

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Clinical Research for Surgeons is a practical guide for understanding, planning, conducting, and evaluating surgical research. It covers the principles of evidence-based surgery and applies these principles to the design of suitable research studies. The reader will come to fully understand important concepts such as case-control study, prospective cohort study, randomized trial, and reliability study. The book provides valuable discussions of the critical appraisal of published clinical studies, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. Highlights: Insights from experienced surgeons and veteran researchers Easy-to-reference text boxes with Key Concepts, Jargon Simplified, and Examples from the Literature Coverage of both open and minimally-invasive surgical procedures 50 illustrations demonstrating key points This book is a valuable reference for clinicians and residents in a range of disciplines, including general surgery, orthopedic surgery, plastic and reconstructive surgery, urology, neurosurgery, otolaryngology-head and neck surgery, interventional radiology, cardiac surgery.


Success in Academic Surgery: Clinical Trials

Success in Academic Surgery: Clinical Trials
Author: Timothy M. Pawlik
Publisher: Springer Science & Business Media
Total Pages: 197
Release: 2013-11-04
Genre: Medical
ISBN: 1447146794

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Surgical education is a rapidly expanding area of surgical research and career interest, and as the Association for Academic Surgery (AAS) Fall Courses (www.aasurg.org) and International courses offer more and more specialty tracking there is a greater need for an accompanying textbook to supplement the material presented in the courses.


Principles of Research Methodology

Principles of Research Methodology
Author: Phyllis G. Supino
Publisher: Springer Science & Business Media
Total Pages: 286
Release: 2012-06-22
Genre: Medical
ISBN: 1461433606

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Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.


Surgical Research

Surgical Research
Author: Hans Troidl
Publisher: Springer Science & Business Media
Total Pages: 685
Release: 2012-12-06
Genre: Medical
ISBN: 1461218888

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A unique reference manual for academic surgeons, this book discusses every facet of surgical research. From getting grant money to choosing a topic, reviewing the literature, planning and conducting research, and reporting results.


Key Topics in Surgical Research and Methodology

Key Topics in Surgical Research and Methodology
Author: Thanos Athanasiou
Publisher: Springer Science & Business Media
Total Pages: 1018
Release: 2010-02-28
Genre: Medical
ISBN: 3540719156

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Key Topics in Surgical Research and Methodology represents a comprehensive reference text accessible to the surgeon embarking on an academic career. Key themes emphasize and summarize the text. Four key elements are covered, i.e. Surgical Research, Research Methodology, Practical Problems and Solutions on Research as well as Recent Developments and Future Prospects in Surgical Research and Practice.