Circular Dichroism And The Conformational Analysis Of Biomolecules PDF Download
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| Author | : G.D. Fasman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 739 |
| Release | : 2013-11-11 |
| Genre | : Science |
| ISBN | : 1475725086 |
Download Circular Dichroism and the Conformational Analysis of Biomolecules Book in PDF, ePub and Kindle
''Excellent and very timely....It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules...An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.
| Author | : Nina Berova |
| Publisher | : John Wiley & Sons |
| Total Pages | : 916 |
| Release | : 2000-05-03 |
| Genre | : Science |
| ISBN | : 9780471330035 |
Download Circular Dichroism Book in PDF, ePub and Kindle
Unter Zirkulardichroismus (CD) versteht man die spezifisch unterschiedliche Absorption von links- und rechtszirkular polarisiertem Licht durch bestimmte Moleküle. CD-Effekte lassen sich in Abhängigkeit von der Wellenlänge messen und spektroskopisch auswerten. Dieser Band erläutert Theorie und Anwendung der CD-Spektroskopie insbesondere für Biomoleküle. Ausführlich behandelt werden Anwendungen auf den Gebieten der organischen Stereochemie und der Biopolymere. Geschrieben von anerkannten Spezialisten! (06/00)
| Author | : Isabel Moraes |
| Publisher | : Springer |
| Total Pages | : 184 |
| Release | : 2016-08-23 |
| Genre | : Science |
| ISBN | : 3319350722 |
Download The Next Generation in Membrane Protein Structure Determination Book in PDF, ePub and Kindle
This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: Expression screening using fluorescent proteins The use of detergents in membrane protein research The use of NMR Synchrotron developments in membrane protein structural biology Visualisation and X-ray data collection of microcrystals X-ray diffraction data analysis from multiple crystals Serial millisecond crystallography Serial femtosecond crystallography Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.
| Author | : Prasad L. Polavarapu |
| Publisher | : CRC Press |
| Total Pages | : 298 |
| Release | : 2016-10-03 |
| Genre | : Science |
| ISBN | : 1315357194 |
Download Chiroptical Spectroscopy Book in PDF, ePub and Kindle
This book details chiroptical spectroscopic methods: electronic circular dichroism (ECD), optical rotatory dispersion (ORD), vibrational circular dichroism (VCD), and vibrational Raman optical activity (VROA). For each technique, the text presents experimental methods for measurements and theoretical methods for analyzing the experimental data. It also includes a set of experiments that can be adopted for undergraduate teaching laboratories. Each chapter is written in an easy-to-follow format for novice readers, with necessary theoretical formalism in appendices for advanced readers.
| Author | : Phoebe A. Rice |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 417 |
| Release | : 2008-05-22 |
| Genre | : Science |
| ISBN | : 0854042725 |
Download Protein-Nucleic Acid Interactions Book in PDF, ePub and Kindle
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
| Author | : Gopalasamudram Ramachandran |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 546 |
| Release | : 2013-06-29 |
| Genre | : Science |
| ISBN | : 1475746024 |
Download Biochemistry of Collagen Book in PDF, ePub and Kindle
Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.
| Author | : Laurence D. Barron |
| Publisher | : Cambridge University Press |
| Total Pages | : 467 |
| Release | : 2009-10-15 |
| Genre | : Science |
| ISBN | : 1139453416 |
Download Molecular Light Scattering and Optical Activity Book in PDF, ePub and Kindle
Ranging from the physics of elementary particles to the structure of viruses, the subject matter of the book reflects the importance of optical activity and chirality in much of modern science and will be of interest to a wide range of physical and life scientists.
| Author | : Laurence A. Nafie |
| Publisher | : John Wiley & Sons |
| Total Pages | : 373 |
| Release | : 2011-07-12 |
| Genre | : Science |
| ISBN | : 1119977533 |
Download Vibrational Optical Activity Book in PDF, ePub and Kindle
This unique book stands as the only comprehensive introduction to vibrational optical activity (VOA) and is the first single book that serves as a complete reference for this relatively new, but increasingly important area of molecular spectroscopy. Key features: A single-source reference on this topic that introduces, describes the background and foundation of this area of spectroscopy. Serves as a guide on how to use it to carry out applications with relevant problem solving. Depth and breadth of the subject is presented in a logical, complete and progressive fashion. Although intended as an introductory text, this book provides in depth coverage of this topic relevant to both students and professionals by taking the reader from basic theory through to practical and instrumental approaches.
| Author | : Ernst David Bergmann |
| Publisher | : Academic Press |
| Total Pages | : 852 |
| Release | : 1973 |
| Genre | : Science |
| ISBN | : |
Download Conformation of Biological Molecules and Polymers Book in PDF, ePub and Kindle
Accuracy of potential functions in the analysis of biopolymer coformation; The dipeptide model-its significance and limitations; Conformational properties of peptides deduced from energy calculations; Interactions in polypertides and proteins; Experimental study of the conformation of dipeptides; Dipole moments and conformations of dipeptides in solution.
| Author | : Alison Rodger |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 170 |
| Release | : 1997 |
| Genre | : Science |
| ISBN | : 9780198558972 |
Download Circular Dichroism and Linear Dichroism Book in PDF, ePub and Kindle
This book provides an introduction to all those who wish to use the complementary spectroscopic techniques of optical activity (circular dichroism, CD) and optical anisotropy (linear dichroism, LD) for the study of the structure of molecules and interactions between molecules in solution. It emphasizes these techniques and how to use them for both low and high molecular weight molecules. The book begins by describing the principles behind CD and LD and how these techniques can be used in the laboratory without using advanced maths or quantum mechanics. The next chapters describe how both techniques may be applied to the study of biological macromolecules and give a detailed description of how they may be used on small molecules to investigate molecular and electronic structure. The final part contains theoretical derivations of all the equations required for the applications described previously. Specific molecular examples are used to illustrate concepts and to show the reader how to use the techniques in chemical and biological systems. Circular Dichroism and Linear Dichroism is an easy guide to what a prospective user of CD needs to know and explains how LD is not merely an exotic technique only to be practiced by experienced spectroscopists, but may be routinely and usefully employed as an aid to molecular structure determination.
