Chromosome Conformation Capture on Chip (4C)
| Author | : Marieke Johanna Simonis |
| Publisher | : |
| Total Pages | : 171 |
| Release | : 2008 |
| Genre | : |
| ISBN | : 9789071382772 |
Download Chromosome Conformation Capture on Chip (4C) Book in PDF, ePub and Kindle
Chromosome Conformation Capture On Chip 4c PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Chromosome Conformation Capture On Chip 4c PDF full book. Access full book title Chromosome Conformation Capture On Chip 4c.
Capturing Chromosome Conformation
| Author | : Beatrice Bodega |
| Publisher | : Humana |
| Total Pages | : 322 |
| Release | : 2020-10-29 |
| Genre | : Science |
| ISBN | : 9781071606636 |
Download Capturing Chromosome Conformation Book in PDF, ePub and Kindle
This detailed book collects methods based on the evolution of the chromosome conformation capture (3C) technique and other complementary approaches to dissect chromatin conformation with an emphasis on dissection of nuclear compartmentalization and visualization in imaging. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Capturing Chromosome Conformation: Methods and Protocols serves as an ideal guide for researchers working to further understand 3D genome organization.
Chromatin Immunoprecipitation Assays
| Author | : Philippe Collas |
| Publisher | : Methods in Molecular Biology |
| Total Pages | : 290 |
| Release | : 2009-08-25 |
| Genre | : Computers |
| ISBN | : |
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In this book, researchers deeply involved in the development and improvement of chromatin immunoprecipitation assays (ChIP) provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects.
Modeling the 3D Conformation of Genomes
| Author | : Guido Tiana |
| Publisher | : CRC Press |
| Total Pages | : 319 |
| Release | : 2019-01-15 |
| Genre | : Science |
| ISBN | : 1351386999 |
Download Modeling the 3D Conformation of Genomes Book in PDF, ePub and Kindle
This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.
Hi-C Data Analysis
| Author | : Silvio Bicciato |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2022-09-04 |
| Genre | : Science |
| ISBN | : 9781071613924 |
Download Hi-C Data Analysis Book in PDF, ePub and Kindle
This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.
Chromatin
| Author | : Randall H. Morse |
| Publisher | : Academic Press |
| Total Pages | : 586 |
| Release | : 2024-06-15 |
| Genre | : Science |
| ISBN | : 0128148101 |
Download Chromatin Book in PDF, ePub and Kindle
Chromatin: Structure, Function, and History covers the basics of chromatin biology, beginning with the discoveries that culminated in the recognition of the nucleosome as the basic subunit of chromatin. Chromatin folding, nucleosome positioning, and histone variants are discussed, as well as research on chromatin modifications and remodeling, which exploded in the early to mid-1990s and led to widespread interest in epigenetics. Considerable attention is given to methods and experiments that led to key insights and recent developments such as the use of genome-wide approaches and innovations in imaging approaches are also emphasized. By providing historical background together with detailed discussion of contemporary studies, the book aims to instill in the reader an appreciation not only of our current knowledge of chromatin structure and function, but also of the remarkable path that has taken chromatin to the forefront of modern research. Provides a current, expansive, and well-documented resource on chromatin and epigenetics Addresses the role of chromatin in transcription regulation and chromatin abnormalities in disease Reviews the historical background of specific areas of chromatin research, enabling readers to understand how the field was born and to appreciate the discoveries and technical advances that have propelled it forward
Chemical Biology of the Genome
| Author | : Siddhartha Roy |
| Publisher | : Academic Press |
| Total Pages | : 352 |
| Release | : 2021-05-14 |
| Genre | : Science |
| ISBN | : 0128176458 |
Download Chemical Biology of the Genome Book in PDF, ePub and Kindle
Chemical Biology of the Genome provides a comprehensive overview of essential concepts and principles of genomic and epigenomics dynamics as explored through the lens of chemical biology. Key examples and case studies illustrate chemical biology methods for study and analysis of the genome and epigenome, with an emphasis on relevance to physiological and pathophysiological processes and drug discovery. Authors and international leaders in biochemical studies of the genome, Drs. Siddhartha Roy and Tapas Kundu, adopt an integrated, interdisciplinary approach throughout, demonstrating how fast evolving chemical and mass-scale sequencing tools are increasingly used to interpret biochemical processes of the genome. Later sections discuss chemical modifications of the genome, DNA sequence recognition by proteins and gene regulation, GWAS and EpiGWAS studies, 3D architecture of the genome, and functional genome architecture. In-depth, discovery focused chapters examine intervention in gene networks using SiRNA/ShRNA, miRNA, and anti-miR, small molecule modulation of iPS, drug resistance pathways altered DNA methylation as drug targets, anti-miR as therapeutics, and nanodelivery of drugs. Offers an interdisciplinary discussion of the chemical biology of the genome and epigenome, employing illustrative case studies in both physiological and pathophysiological contexts Supports researchers in employing chemical and mass-scale sequencing approaches to interpret genomic and epigenomic dynamics Highlights innovative pathways and molecular targets for new disease study and drug discovery
Next-Generation Genome Sequencing
| Author | : Michal Janitz |
| Publisher | : John Wiley & Sons |
| Total Pages | : 281 |
| Release | : 2011-08-24 |
| Genre | : Science |
| ISBN | : 3527644733 |
Download Next-Generation Genome Sequencing Book in PDF, ePub and Kindle
Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.
Principles of Virology, Volume 1
| Author | : Jane Flint |
| Publisher | : John Wiley & Sons |
| Total Pages | : 610 |
| Release | : 2020-11-03 |
| Genre | : Science |
| ISBN | : 1683672844 |
Download Principles of Virology, Volume 1 Book in PDF, ePub and Kindle
Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to under-stand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.
Principles of Virology
| Author | : Jane Flint |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1136 |
| Release | : 2020-08-07 |
| Genre | : Science |
| ISBN | : 1683670337 |
Download Principles of Virology Book in PDF, ePub and Kindle
Principles of Virology, the leading virology textbook in use, is an extremely valuable and highly informative presentation of virology at the interface of modern cell biology and immunology. This text utilizes a uniquely rational approach by highlighting common principles and processes across all viruses. Using a set of representative viruses to illustrate the breadth of viral complexity, students are able to understand viral reproduction and pathogenesis and are equipped with the necessary tools for future encounters with new or understudied viruses. This fifth edition was updated to keep pace with the ever-changing field of virology. In addition to the beloved full-color illustrations, video interviews with leading scientists, movies, and links to exciting blogposts on relevant topics, this edition includes study questions and active learning puzzles in each chapter, as well as short descriptions regarding the key messages of references of special interest. Volume I: Molecular Biology focuses on the molecular processes of viral reproduction, from entry through release. Volume II: Pathogenesis and Control addresses the interplay between viruses and their host organisms, on both the micro- and macroscale, including chapters on public health, the immune response, vaccines and other antiviral strategies, viral evolution, and a brand new chapter on the therapeutic uses of viruses. These two volumes can be used for separate courses or together in a single course. Each includes a unique appendix, glossary, and links to internet resources. Principles of Virology, Fifth Edition, is ideal for teaching the strategies by which all viruses reproduce, spread within a host, and are maintained within populations. This edition carefully reflects the results of extensive vetting and feedback received from course instructors and students, making this renowned textbook even more appropriate for undergraduate and graduate courses in virology, microbiology, and infectious diseases.
