Chromatographic Methods In Metabolomics PDF Download
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Author | : Tuulia Hyotylainen |
Publisher | : Royal Society of Chemistry |
Total Pages | : 259 |
Release | : 2013-09-06 |
Genre | : Science |
ISBN | : 1849737274 |
Download Chromatographic Methods in Metabolomics Book in PDF, ePub and Kindle
The concept of a metabolic profile was introduced in 1971, when gas chromatography demonstrated a range of compounds present in human samples. Now termed metabolomics, the field is still emerging, and chromatography remains an essential tool for determining metabolites in a living system. This is the first book to present the chromatographic techniques used in metabolomics in a fundamental way. Sample preparation and quality control are described in detail, and all forms of chromatography applied to metabolomics are included. The editors present guidelines on selecting the most appropriate methodology, making the book an accessible guide to anyone entering the field. Handling data and applications are also described. This is an essential handbook for any laboratory looking to embark on a metabolomics research programme and includes the fundamentals of chromatography alongside the latest developments in the field.
Author | : Tuulia Hyotylainen |
Publisher | : Royal Society of Chemistry |
Total Pages | : 258 |
Release | : 2013 |
Genre | : Science |
ISBN | : 1849736073 |
Download Chromatographic Methods in Metabolomics Book in PDF, ePub and Kindle
Intends to present chromatographic techniques in metabolomics in a fundamental way. This book covers the chromatographic techniques, such as liquid chromatography, gas chromatography, comprehensive two-dimensional gas chromatography and electrochromatographic techniques utilised in metabolomics.
Author | : Wolfram Weckwerth |
Publisher | : Springer Science & Business Media |
Total Pages | : 290 |
Release | : 2008-02-04 |
Genre | : Science |
ISBN | : 1597452440 |
Download Metabolomics Book in PDF, ePub and Kindle
Metabolomics: Methods and Protocols examines the state-of-the-art in metabolomic analysis. Leading researchers in the field present protocols for the application of complementary analytical methods, such as gas chromatography-mass spectrometry (GC-MS). Metabolomics: Methods and Protocols contains forward-looking protocols, which provide the essential groundwork for future efforts in elucidating the structure of the unknowns detected in metabolomic studies.
Author | : Haleem J. Issaq |
Publisher | : Academic Press |
Total Pages | : 489 |
Release | : 2013-05-20 |
Genre | : Science |
ISBN | : 0123947952 |
Download Proteomic and Metabolomic Approaches to Biomarker Discovery Book in PDF, ePub and Kindle
Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. Describes the use of biomarkers to reduce clinical errors in research Includes techniques from a range of biomarker discoveries Covers all steps involved in biomarker discovery, from study design to study execution
Author | : Rawi Ramautar |
Publisher | : Royal Society of Chemistry |
Total Pages | : 367 |
Release | : 2021-07-21 |
Genre | : Science |
ISBN | : 1839161639 |
Download Advanced Mass Spectrometry-based Analytical Separation Techniques for Probing the Polar Metabolome Book in PDF, ePub and Kindle
Discussing the state-of-the-art of the proposed topics in one single book for probing the polar metabolome, using relevant examples, is unique and needed in the metabolomics field.
Author | : Kazuki Saito |
Publisher | : Springer Science & Business Media |
Total Pages | : 351 |
Release | : 2006-06-29 |
Genre | : Science |
ISBN | : 3540297820 |
Download Plant Metabolomics Book in PDF, ePub and Kindle
Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Author | : Paul L. Wood |
Publisher | : Humana |
Total Pages | : 307 |
Release | : 2021-11-15 |
Genre | : Medical |
ISBN | : 9781071608661 |
Download Metabolomics Book in PDF, ePub and Kindle
This volume discusses the latest analytical approaches used to sample defined molecular populations of metabolites via functional group derivatization, specialized chromatographic methods, and ionization techniques. Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. Chapters also explore non-targeted and targeted analyses, as well as the emerging field of metallomics. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Metabolomics is a valuable resource for students, researchers, practicing physicians and veterinarians, and administrators involved in the funding of research.
Author | : Julia Kuligowski |
Publisher | : MDPI |
Total Pages | : 206 |
Release | : 2021-04-07 |
Genre | : Medical |
ISBN | : 3039438131 |
Download Sample Preparation in Metabolomics Book in PDF, ePub and Kindle
Metabolomics is increasingly being used to explore the dynamic responses of living systems in biochemical research. The complexity of the metabolome is outstanding, requiring the use of complementary analytical platforms and methods for its quantitative or qualitative profiling. In alignment with the selected analytical approach and the study aim, sample collection and preparation are critical steps that must be carefully selected and optimized to generate high-quality metabolomic data. This book showcases some of the most recent developments in the field of sample preparation for metabolomics studies. Novel technologies presented include electromembrane extraction of polar metabolites from plasma samples and guidelines for the preparation of biospecimens for the analysis with high-resolution μ magic-angle spinning nuclear magnetic resonance (HR-μMAS NMR). In the following chapters, the spotlight is on sample preparation approaches that have been optimized for diverse bioanalytical applications, including the analysis of cell lines, bacteria, single spheroids, extracellular vesicles, human milk, plant natural products and forest trees.
Author | : Silas G. Villas-Boas |
Publisher | : John Wiley & Sons |
Total Pages | : 339 |
Release | : 2007-02-16 |
Genre | : Science |
ISBN | : 047010550X |
Download Metabolome Analysis Book in PDF, ePub and Kindle
Providing information on the main approaches for the analysis of metabolites, this textbook: Covers basic methodologies in sample preparation and separation techniques, as well as the most recent techniques of mass spectrometry. Differentiates between primary and secondary metabolites. Includes four chapters discussing successful metabolome studies of different organisms. Highlights the analytical challenges of studying metabolites. Illustrates applications of metabolome analysis through the use of case studies.
Author | : Paul L. Wood |
Publisher | : |
Total Pages | : |
Release | : 2021 |
Genre | : Metabolites |
ISBN | : 9781071608647 |
Download Metabolomics Book in PDF, ePub and Kindle
This volume discusses the latest analytical approaches used to sample defined molecular populations of metabolites via functional group derivatization, specialized chromatographic methods, and ionization techniques. Chapters cover key methods for sample introductions to the ion source, including direct flow, gas chromatography, liquid chromatography, and capillary electrophoresis. Chapters also explore non-targeted and targeted analyses, as well as the emerging field of metallomics. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Metabolomics is a valuable resource for students, researchers, practicing physicians and veterinarians, and administrators involved in the funding of research.