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Medical Sensors And Lab-on-a-chip Devices: Mechanisms, Biofunctionalization And Measurement Techniques

Medical Sensors And Lab-on-a-chip Devices: Mechanisms, Biofunctionalization And Measurement Techniques
Author: Vinod Kumar Khanna
Publisher: World Scientific
Total Pages: 743
Release: 2018-02-14
Genre: Medical
ISBN: 9813221259

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This book provides a comprehensive coverage of sensor and lab-on-a-chip technologies for medical applications. Presenting a unified coverage of the operational principles and fabrication issues of the sensors and related chips, this important compendium describes the contemporary electronic devices that help to identify and effectively combat different diseases and malfunctions of the human body. It is intended to serve as an essential textbook or reference book for graduate/postgraduate students in electrical and electronic engineering, biomedical engineering, and those pursuing a course on sensor technologies in medicine. Research students and scientists too will find the self-explanatory diagrams and end-of-chapter bibliographies very useful.


Nanobiosensors for Personalized and Onsite Biomedical Diagnosis

Nanobiosensors for Personalized and Onsite Biomedical Diagnosis
Author: Pranjal Chandra
Publisher: IET
Total Pages: 637
Release: 2016-07-21
Genre: Medical
ISBN: 1849199507

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The critical goal of nanobiosensors is to detect any biochemical and/or biophysical signal related to a specific disease at the level of a single or few molecules. Nanobiosensors have been successful for in vitro as well as in vivo detection of several biomolecules. It is expected that this technology will revolutionize point-of-care and personalized diagnostics, and will be extremely applicable for early disease detection. This book starts with a brief introduction of the biosensors and then focuses mainly on the emerging nanobiosensor technologies which are geared towards onsite clinical applications and those which can be used as a personalized diagnostic device. Written by an international team of researchers who are actively developing these technologies, Nanobiosensors for Personalized and Onsite Biomedical Diagnosis covers the latest advances in the field of biosensors and biosensing applications. This important book includes an assessment of some current and emerging technologies for detecting protein biomarkers and other potential cancer biomarkers and is essential reading for researchers and graduate students in the field. Medics including radiologists and clinicians will also find it invaluable.


Sensors for Diagnostics and Monitoring

Sensors for Diagnostics and Monitoring
Author: Kevin Yallup
Publisher: CRC Press
Total Pages: 352
Release: 2018-09-03
Genre: Technology & Engineering
ISBN: 1351250086

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Sensor technologies and applications are evolving rapidly driven by the demand for new sensors for monitoring and diagnostic purposes to enable improvements in human health and safety. Simultaneously, sensors are required to consume less power, be autonomous, cost less, and be connected by the Internet of Things. New sensor technologies are being developed to fulfill these needs. This book reviews the latest developments in sensor technology and gives the reader an overview of the state-of-the-art in key areas, such as sensors for diagnostics and monitoring. Features Provides an overview of sensor technologies for monitoring and diagnostics applications. Presents state-of-the-art developments in selected topics for sensors that can be used for monitoring and diagnostics in future healthcare, structural monitoring, and smart environment applications. Features contributions from leading international experts in both industry and academia. Explores application areas that include medical diagnostics and screening, health monitoring, smart textiles, and structural monitoring.


Point-of-Care Biosensors for Infectious Diseases

Point-of-Care Biosensors for Infectious Diseases
Author: Sushma Dave
Publisher: John Wiley & Sons
Total Pages: 309
Release: 2023-06-21
Genre: Science
ISBN: 3527837965

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Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.


Modern Techniques in Biosensors

Modern Techniques in Biosensors
Author: Gorachand Dutta
Publisher: Springer Nature
Total Pages: 316
Release: 2021-01-04
Genre: Technology & Engineering
ISBN: 9811596123

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This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation and user-friendliness). Different advanced techniques including electrochemical, optical, mass, colorimetric and signal amplification strategies describe early stage disease diagnosis. The book gathers scientific and technological novelties and advancements already developed or under development in the academic and research communities. It covers a vast audience from basic science to engineering and technology experts and learners.


Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics

Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics
Author: Gorachand Dutta
Publisher: Springer Nature
Total Pages: 252
Release: 2022-12-02
Genre: Science
ISBN: 9811971307

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This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. ​


Sensors for Health Monitoring

Sensors for Health Monitoring
Author: Nilanjan Dey
Publisher: Academic Press
Total Pages: 322
Release: 2019-09-09
Genre: Technology & Engineering
ISBN: 012819362X

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Sensors for Health Monitoring discusses the characteristics of U-Healthcare systems in different domains, providing a foundation for working professionals and undergraduate and postgraduate students. The book provides information and advice on how to choose the best sensors for a U-Healthcare system, advises and guides readers on how to overcome challenges relating to data acquisition and signal processing, and presents comprehensive coverage of up-to-date requirements in hardware, communication and calculation for next-generation uHealth systems. It then compares new technological and technical trends and discusses how they address expected u-Health requirements. In addition, detailed information on system operations is presented and challenges in ubiquitous computing are highlighted. The book not only helps beginners with a holistic approach toward understanding u-Health systems, but also presents researchers with the technological trends and design challenges they may face when designing such systems. Presents an outstanding update on the use of U-Health data analysis and management tools in different applications, highlighting sensor systems Highlights Internet of Things enabled U-Healthcare Covers different data transmission techniques, applications and challenges with extensive case studies for U-Healthcare systems


Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis

Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis
Author: Pranjal Chandra
Publisher: Springer
Total Pages: 403
Release: 2017-12-30
Genre: Medical
ISBN: 981104726X

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This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.


Oral Cancer Detection

Oral Cancer Detection
Author: Prashanth Panta
Publisher: Springer
Total Pages: 314
Release: 2019-01-04
Genre: Medical
ISBN: 3319612557

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This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.