Chemistry Of Protein And Nucleic Acid Cross Linking And Conjugation PDF Download
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Author | : Shan S. Wong |
Publisher | : CRC Press |
Total Pages | : 608 |
Release | : 2011-10-10 |
Genre | : Medical |
ISBN | : 1420007645 |
Download Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation Book in PDF, ePub and Kindle
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross
Author | : Shan S. Wong |
Publisher | : CRC Press |
Total Pages | : 360 |
Release | : 1991-06-18 |
Genre | : Medical |
ISBN | : 9780849358869 |
Download Chemistry of Protein Conjugation and Cross-Linking Book in PDF, ePub and Kindle
Chemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.
Author | : Greg T. Hermanson |
Publisher | : Academic Press |
Total Pages | : 1233 |
Release | : 2010-07-26 |
Genre | : Science |
ISBN | : 0080568726 |
Download Bioconjugate Techniques Book in PDF, ePub and Kindle
Bioconjugate Techniques, 2nd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or cross linking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates More than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates Includes entirely new chapters on the latest areas in the field of bioconjugation as follows: Microparticles and nanoparticlesSilane coupling agentsDendrimers and dendronsChemoselective ligationQuantum dotsLanthanide chelatesCyanine dyesDiscrete PEG compoundsBuckyballs,fullerenes, and carbon nanotubesMass tags and isotope tagsBioconjugation in the study of protein interactions
Author | : S.S. Deshpande |
Publisher | : Springer Science & Business Media |
Total Pages | : 473 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461311691 |
Download Enzyme Immunoassays Book in PDF, ePub and Kindle
This unique reference provides a pragmatic approach to the development of successful commercial immunodiagnostic products based on enzyme immunoessay technology. Presenting both the basic and applied principles, Enzyme Immunoassays gathers information on all aspects of this process, from the initial conceptualization to the introduction of the product to the market.
Author | : Kazuhiko Nakatani |
Publisher | : Springer |
Total Pages | : 276 |
Release | : 2016-04-04 |
Genre | : Science |
ISBN | : 3319271113 |
Download Modified Nucleic Acids Book in PDF, ePub and Kindle
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Author | : Greg T. Hermanson |
Publisher | : Academic Press |
Total Pages | : 1166 |
Release | : 2013-07-25 |
Genre | : Science |
ISBN | : 0123822408 |
Download Bioconjugate Techniques Book in PDF, ePub and Kindle
Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented
Author | : Floris van Delft |
Publisher | : Royal Society of Chemistry |
Total Pages | : 477 |
Release | : 2021-12-22 |
Genre | : Medical |
ISBN | : 1839162635 |
Download Chemical Linkers in Antibody-Drug Conjugates (ADCs) Book in PDF, ePub and Kindle
Chemical Linkers in Antibody-Drug Conjugates aims to shine a detailed light on the various key attributes of chemical linkers in ADCs, for drug-to-antibody ratio, for stability, for release mechanism of payload, for pharmacokinetics, for stability determination, and for efficacy and safety.
Author | : Michael J Waring |
Publisher | : Royal Society of Chemistry |
Total Pages | : 432 |
Release | : 2018-03-08 |
Genre | : Science |
ISBN | : 1788014286 |
Download DNA-targeting Molecules as Therapeutic Agents Book in PDF, ePub and Kindle
There have been remarkable advances towards discovering agents that exhibit selectivity and sequence-specificity for DNA, as well as understanding the interactions that underlie its propensity to bind molecules. This progress has important applications in many areas of biotechnology and medicine, notably in cancer treatment as well as in future gene targeting therapies. The editor and contributing authors are leaders in their fields and provide useful perspectives from diverse and interdisciplinary backgrounds on the current status of this broad area. The role played by chemistry is a unifying theme. Early chapters cover methodologies to evaluate DNA-interactive agents and then the book provides examples of DNA-interactive molecules and technologies in development as therapeutic agents. DNA-binding metal complexes, peptide and polyamide–DNA interactions, and gene targeting tools are some of the most compelling topics treated in depth. This book will be a valuable resource for postgraduate students and researchers in chemical biology, biochemistry, structural biology and medicinal fields. It will also be of interest to supramolecular chemists and biophysicists.
Author | : Insup Noh |
Publisher | : Royal Society of Chemistry |
Total Pages | : 505 |
Release | : 2021-07-30 |
Genre | : Technology & Engineering |
ISBN | : 1788018834 |
Download Injectable Hydrogels for 3D Bioprinting Book in PDF, ePub and Kindle
Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering. Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications. Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.
Author | : Sabine M¿ller |
Publisher | : John Wiley & Sons |
Total Pages | : 350 |
Release | : 2008-09-08 |
Genre | : Science |
ISBN | : 3527622535 |
Download Nucleic Acids from A to Z Book in PDF, ePub and Kindle
Concise but complete, this mini-encyclopedia contains over 1,500 entries covering all important concepts, compounds, techniques and acronyms for quick and easy reference. Guiding readers through the ever-increasing jungle of nucleic acid science and technology, the book distills the key information out of the large body of primary literature and presents it in a single volume. A first-stop resource for everyone, from students to established researchers, as both a desktop and library reference.