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The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry
Author: Camille Georges Wermuth
Publisher: Elsevier
Total Pages: 792
Release: 2003-06-11
Genre: Science
ISBN: 0080497772

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The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. The only book available dealing with the practical aspects of medicinal chemistry Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry


The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry
Author: Camille Georges Wermuth
Publisher: Elsevier
Total Pages: 903
Release: 2015-07-01
Genre: Science
ISBN: 012417213X

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The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research An image bank is available for instructors at www.textbooks.elsevier.com


The Chemistry of Medicines, Practical

The Chemistry of Medicines, Practical
Author: John Uri Lloyd
Publisher: Forgotten Books
Total Pages: 484
Release: 2018-02-10
Genre: Science
ISBN: 9780656248384

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Excerpt from The Chemistry of Medicines, Practical: A Text and Reference Book for the Use of Students, Physicians, and Pharmacists, Embodying the Principles of Chemical Philosophy and Their Application to Those Chemicals That Are Used in Medicine and in Pharmacy The fact that the first edition of this work was entirely disposed of within a month from the time of its publica tion, taken in connection with the many complimentary and favorable notices ofit from the foremost medical and pharmaceutical journals of our country, as well as from numerous teachers of medicine and of pharmacy, has led me to hope that it may meet with a more extensive cir culation, and prove of greater utility, than I could at first reasonably anticipate. I have therefore been induced to present this second and improved edition. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.


The Chemistry of Medicines, Practical

The Chemistry of Medicines, Practical
Author: John Uri Lloyd
Publisher: Andesite Press
Total Pages: 470
Release: 2017-08-20
Genre: History
ISBN: 9781375758192

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Medicinal Chemistry

Medicinal Chemistry
Author: Frank D. King
Publisher:
Total Pages: 348
Release: 1994
Genre: Medical
ISBN:

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An introduction to the subject, aimed primarily at synthetic chemists, which explains how to identify a drug candidate from an initial lead compound that possesses the properties required for successful development. The main aim of the text is to address the quality of interpretations.


Handbook of Medicinal Chemistry

Handbook of Medicinal Chemistry
Author: Simon E Ward
Publisher: Royal Society of Chemistry
Total Pages: 1436
Release: 2023-02-03
Genre: Medical
ISBN: 183916588X

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Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.


The Chemistry of Medicines, Practical

The Chemistry of Medicines, Practical
Author: John Uri Lloyd
Publisher: Palala Press
Total Pages: 458
Release: 2016-05-20
Genre:
ISBN: 9781357827182

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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.


Practical Medicinal Chemistry with Macrocycles

Practical Medicinal Chemistry with Macrocycles
Author: Eric Marsault
Publisher: John Wiley & Sons
Total Pages: 617
Release: 2017-09-12
Genre: Science
ISBN: 1119092566

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Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations