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| Author | : David E. Newton |
| Publisher | : Infobase Publishing |
| Total Pages | : 193 |
| Release | : 2007 |
| Genre | : Chemistry |
| ISBN | : 1438109717 |
Discusses current research and advances in the field of pharmaceutical chemistry, including drug safety, designer drugs, and the development of new drugs.
| Author | : Alex Gringauz |
| Publisher | : Wiley-VCH |
| Total Pages | : 744 |
| Release | : 1997 |
| Genre | : Medical |
| ISBN | : |
This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.
| Author | : Guo-Qiang Lin |
| Publisher | : John Wiley & Sons |
| Total Pages | : 469 |
| Release | : 2011-08-08 |
| Genre | : Science |
| ISBN | : 1118075633 |
An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.
| Author | : A.K. Ganguly |
| Publisher | : CRC Press |
| Total Pages | : 118 |
| Release | : 2021-09-12 |
| Genre | : Medical |
| ISBN | : 1000437213 |
Medicinal Chemistry: A Look at How Drugs Are Discovered is written for those who are interested in learning how drugs are discovered. Compared to other books on the market, this text takes a different approach by presenting the subject on chemical reaction mechanism terms, which ideally makes the subject matter more interesting and easier to comprehend. The authors describe the drug discovery process, from advancing an initial lead to the approval process, and include drug discovery sources. Additional features: Explains medicinal chemistry on chemical mechanism terms, allowing for a more interesting and easier to comprehend text Includes valuable insights toward the various pathways taken at pharmaceutical industries in drug discoveries Improved by including questions raised and suggestions made from students in the authors’ medicinal chemistry classes This book will benefit both upper level undergraduates and graduates studying in the fields of medicinal chemistry and drug discovery, as well as scientists working in the pharmaceutical industry.
| Author | : David Barlow |
| Publisher | : Pharmaceutical Press |
| Total Pages | : 273 |
| Release | : 2014-07-02 |
| Genre | : Medical |
| ISBN | : 0857110837 |
A revision guide on pharmaceutical and medicinal chemistry. The book covers all aspects of the chemistry of drugs and includes key points, tips, and self-assessment questions to aid in learning.
| Author | : Stephen R. Byrn |
| Publisher | : Ssci |
| Total Pages | : 608 |
| Release | : 1999 |
| Genre | : Drugs |
| ISBN | : |
| Author | : Daniel M. Perrine |
| Publisher | : |
| Total Pages | : 504 |
| Release | : 1996 |
| Genre | : Medical |
| ISBN | : |
This fascinating book presents a scientifically objective, and thoroughly documented exposition of the pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to Zopiclone. It also features first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used, and discusses historical allusions to many literary and scientific figures who used or wrote of mind-altering drugs, including Freud, Dickens, Yeats, and Huxley. Intended for a wide audience of general readers seeking unbiased information, the book gives an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. Written by an experienced chemist, the book nevertheless keeps technical information to a minimum.
| Author | : Richard B. Silverman |
| Publisher | : Elsevier |
| Total Pages | : 650 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0080513379 |
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization
| Author | : Carmen Avendaño |
| Publisher | : Elsevier |
| Total Pages | : 767 |
| Release | : 2015-06-11 |
| Genre | : Science |
| ISBN | : 0444626670 |
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature
| Author | : Douglas S. Johnson |
| Publisher | : John Wiley & Sons |
| Total Pages | : 295 |
| Release | : 2013-02-26 |
| Genre | : Science |
| ISBN | : 111867846X |
The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.
