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Chemical Neuroanatomy of the Prenatal Rat Brain

Chemical Neuroanatomy of the Prenatal Rat Brain
Author: George Alan Foster
Publisher: Oxford University Press, USA
Total Pages: 0
Release: 1998
Genre: Brain
ISBN: 9780198542179

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There are other rat brain atlases available, but this is the definitive atlas of the early and late gestational age rat brain. It shows the development of anatomical structures from embryonic day 13 to the day of birth, using section-by-section photomicrographs together with accompanyingline diagrams. Over 750 structures are identified, giving functional as well as anatomical descriptions, including up to eight transmitter-delineated cell groups on each accompanying map. The emphasis throughout is on facilitating the identification of structures for those without advancedtraining in anatomy, enhanced by a comprehensive index of structures, abbreviations, temporal appearance, and spatial orientation to make pathfinding as easy as possible. With over 230 micrographs of superb quality, Chemical neuroanatomy of the prenatal rat brain: a developmental atlas will be anessential resource for all researchers in developmental and molecular neurobiology.


Atlas of Prenatal Rat Brain Development

Atlas of Prenatal Rat Brain Development
Author: Joseph Altman
Publisher: CRC Press
Total Pages: 664
Release: 1994-11-21
Genre: Science
ISBN: 9780849389931

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The result of 3 decades of original research and instruction by internationally referenced authors, Drs. Joseph Altman and Shirley A. Bayer, the Atlas of Prenatal Rat Brain Development provides a complete, state-of-the-art presentation of the developing prenatal rat brain. With the aid of advanced computer graphics, Altman and Bayer revolutionize the study of the highly vulnerable prenatal brain and bring us closer to understanding the dynamics of its development, its malfunctions, deficits, and abnormalities. Their contributions to the field of brain research, and hence to our knowledge of brain disorders, are unsurpassed. The Atlas contains more than 265 platesÛeach plate accompanied by a computer-aided drawing, a 3-dimensional reconstruction of brain slices never before achieved with such accuracy and clarity, that assists in the visualization of the brain and of the relationships among various brain regions. A new, user-friendly alphanumeric coding system is used, allowing for easy identification of brain regions.


Atlas of the Developing Mouse Brain at E17.5, P0 and P6

Atlas of the Developing Mouse Brain at E17.5, P0 and P6
Author: George Paxinos
Publisher: Academic Press
Total Pages: 378
Release: 2007
Genre: Science
ISBN: 0125476221

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This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.


From Neurons to Neighborhoods

From Neurons to Neighborhoods
Author: National Research Council
Publisher: National Academies Press
Total Pages: 610
Release: 2000-11-13
Genre: Social Science
ISBN: 0309069882

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How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.


Atlas of the Developing Rat Nervous System

Atlas of the Developing Rat Nervous System
Author: George Paxinos
Publisher: Academic Press
Total Pages: 541
Release: 2018-02-09
Genre: Medical
ISBN: 0128131144

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Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility. Provides detailed and accurate coverage of the developing rat nervous system from Embryonic Day 11 to Day of Birth Contains 200 photographs and accompanying diagrams of coronal or sagittal sections of rats aged E11 – E19 Presents new sections on Histology, Neurogenetics, Imaging, MRI Histology and Panneuronal Markers Delineates brain structures and peripheral nerves, ganglia, arteries, veins, muscles, bones and other important organs Serves as an essential tool for researchers in the interpretation of findings resulting from the genetic manipulation of brain development Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content


The Newborn Brain

The Newborn Brain
Author: Hugo Lagercrantz
Publisher: Cambridge University Press
Total Pages: 568
Release: 2002
Genre: Medical
ISBN: 9780521793384

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At a time of rapid advances, this is a uniquely authoritative survey of brain development for scientists and clinicians alike.


Handbook of Neurotoxicity

Handbook of Neurotoxicity
Author: Richard M. Kostrzewa
Publisher: Springer Nature
Total Pages: 2551
Release: 2023-01-02
Genre: Medical
ISBN: 3031150805

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This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.


Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates, Compact

Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates, Compact
Author: Keith B.J. Franklin
Publisher: Elsevier
Total Pages: 654
Release: 2019-05-23
Genre: Medical
ISBN: 0128161957

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Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery. Contains 100 coronal diagrams that were fully revised for this new edition Includes 100 coronal photographic plates produced from directly scanned, very high-resolution images of the biological sections (done at the Allen Institute) Provides a beginner's guide with 25 pages on conducting stereotaxic surgery and how to use the atlas Presents surface views of the brain with labels over the major structures Uses the best ontology tree (nomenclature based on the development of the brain) with universal applications across mammals


Mouse Brain Development

Mouse Brain Development
Author: Andre M. Goffinet
Publisher: Springer Science & Business Media
Total Pages: 347
Release: 2012-08-10
Genre: Science
ISBN: 3540480021

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Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.


Neural Transplantation Methods

Neural Transplantation Methods
Author: Stephen B. Dunnett
Publisher: Springer Science & Business Media
Total Pages: 554
Release: 1999-10-20
Genre: Medical
ISBN: 0896037932

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we might seek alternative sources of donor tissues. Genetic en- neering, expansion of precursor cells, generation of immortalized cell lines, and transplantation between species are all under active investigation. Although significant difficulties remain for each of these alternatives, the problems appear soluble and relevant knowledge is expanding rapidly. As we enter the twenty-first century, the place of neural tra- plantation in experimental neuroscience is continuing to evolve. Rather than being a topic in its own right, neural transplantation increasingly serves as just another technique in the researcher's armory--alongside lesions, pharmaceuticals, gene transfer, and a variety of other techniques--for the experimental manipulation of brain structure and function. This is particularly true for studies of degeneration, plasticity, regeneration, and recovery of function in the nervous system, topics of increasing importance as experimental neurobiology is required to serve the higher needs of neurological and mental health in aging societies. Within this evolving context, Neural Transplantation Methods seeks to serve a particular need: to provide experimental neu- scientists with a source book of information to enable them to select and adapt transplantation techniques to their own expe- mental programs. All authors have been asked to address prac- cal issues, to enable the reader to assess what is available, what are the alternatives, what are the practical issues to be resolved in applying a particular protocol and getting it to work reliably in their unique experimental context.