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| Author | : Satyendra Chandra Tripathi |
| Publisher | : Frontiers Media SA |
| Total Pages | : 336 |
| Release | : 2021-03-01 |
| Genre | : Science |
| ISBN | : 2889665232 |
| Author | : Bharat B. Aggarwal |
| Publisher | : Springer |
| Total Pages | : 489 |
| Release | : 2014-05-12 |
| Genre | : Medical |
| ISBN | : 3034808372 |
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
| Author | : Dipayan Rudra |
| Publisher | : Frontiers Media SA |
| Total Pages | : 246 |
| Release | : 2023-03-01 |
| Genre | : Medical |
| ISBN | : 2832515843 |
| Author | : Mohit Kumar Jolly |
| Publisher | : MDPI |
| Total Pages | : 512 |
| Release | : 2020-12-29 |
| Genre | : Medical |
| ISBN | : 3039367242 |
Recent studies have highlighted that epithelial-mesenchymal transition (EMT) is not only about cell migration and invasion, but it can also govern many other important elements such as immunosuppression, metabolic reprogramming, senescence-associated secretory phenotype (SASP), stem cell properties, therapy resistance, and tumor microenvironment interactions. With the on-going debate about the requirement of EMT for cancer metastasis, an emerging focus on intermediate states of EMT and its reverse process mesenchymal-epithelial transition (MET) offer new ideas for metastatic requirements and the dynamics of EMT/MET during the entire metastatic cascade. Therefore, we would like to initiate discussions on viewing EMT and its downstream signaling networks as a fulcrum of cellular plasticity, and a facilitator of the adaptive responses of cancer cells to distant organ microenvironments and various therapeutic assaults. We hereby invite scientists who have prominently contributed to this field, and whose valuable insights have led to the appreciation of epithelial-mesenchymal plasticity as a more comprehensive mediator of the adaptive response of cancer cells, with huge implications in metastasis, drug resistance, tumor relapse, and patient survival.
| Author | : Sam Thiagalingam |
| Publisher | : Cambridge University Press |
| Total Pages | : 597 |
| Release | : 2015-04-09 |
| Genre | : Mathematics |
| ISBN | : 0521493390 |
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
| Author | : Robert Clarke |
| Publisher | : Springer |
| Total Pages | : 220 |
| Release | : 2019-03-01 |
| Genre | : Medical |
| ISBN | : 303005067X |
This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR components affect cancer cell biology and responsiveness to therapeutic interventions, and how UPR components/activities offer potentially novel targets for drug discovery, repurposing, and development. The volume will provide the most recent information on the signaling and regulation of the UPR, explore examples of how the UPR and/or specific components contribute to cancer biology, and identify and explore specific examples of potently new actionable targets for drug discovery and development from within the UPR and its regulation. Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.
| Author | : Kenneth Wilson |
| Publisher | : Cambridge University Press |
| Total Pages | : 693 |
| Release | : 2019-11-14 |
| Genre | : Mathematics |
| ISBN | : 1107136563 |
Introduces readers to key case studies that illustrate how theory and data can be integrated to understand wildlife disease ecology.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 560 |
| Release | : 2011-07-01 |
| Genre | : Medical |
| ISBN | : 0309211093 |
A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2009 |
| Genre | : Bioinformatics |
| ISBN | : 9780879699154 |
| Author | : Lucio Comai |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2017-02-11 |
| Genre | : Science |
| ISBN | : 9781493967452 |
This volume aims to provide protocols on a wide range of biochemical methods, analytical approaches, and bioinformatics tools developed to analyze the proteome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Proteomics: Methods and Protocols aims to ensure successful results in the further study of this vital field.
