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Changing Paradigms in the Management of Breast Cancer

Changing Paradigms in the Management of Breast Cancer
Author: Marissa Howard-McNatt
Publisher: Springer
Total Pages: 243
Release: 2017-09-12
Genre: Medical
ISBN: 3319603361

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This text is designed to present a comprehensive and state-of the-art approach to the management of breast cancer within the fields of surgery, medical oncology, and radiation oncology. Sections address changes in these fields. These areas include breast imaging, management of the axilla, atypical breast lesions, surgical margins, new techniques in breast reconstruction, and nipple sparing and contralateral mastectomies. Subsequent chapters focus on issues in medical oncology including, triple negative breast cancer and metastatic breast disease. New paradigms in radiation oncology are examined. Breast cancer treatment in the elderly and in young women, and genetic risk in breast cancer management is also be discussed. Written by experts in their field, each of these sections addresses advances and changes in the field. A brief review of the existing literature addressing the particular topic follows in each section. The text concludes with chapters on pathological issues and advances in radiation oncology. As access to a comprehensive multidisciplinary resource such as this is currently limited in the literature, Changing Paradigms in the Management of Breast Cancer represents the first single source to provide information on advances and outcomes for the physician caring for breast cancer patients in a multidisciplinary setting.


Changing Paradigms in Breast Cancer Diagnosis and Treatment, An Issue of Surgical Oncology Clinics of North America, E-Book

Changing Paradigms in Breast Cancer Diagnosis and Treatment, An Issue of Surgical Oncology Clinics of North America, E-Book
Author: Kelly K. Hunt
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2017-11-21
Genre: Medical
ISBN: 032356660X

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This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Kelly Hunt, is devoted to Changing Paradigms in Breast Cancer Diagnosis and Treatment. Dr. Hunt has assembled expert authors to review the following topics: Tomosynthesis in breast cancer imaging: how does it fit into preoperative evaluation and surveillance?; Lobular breast cancer: different disease, different algorithms?; Hypofractionated radiation therapy in breast conserving therapy; Oncoplastic breast reconstruction: should all patients be considered?; Neoadjuvant endocrine therapy: who benefits most?; Breast cancer disparities: how can we leverage genomics to improve outcomes?; Anatomy and breast cancer staging: is it still relevant?; When does atypical ductal hyperplasia require surgical intervention?; Surgical intervention for lymphedema; Are there alternative strategies in the local management of DCIS?; Genetic testing and genetic counseling: what is standard of care?; Molecular subtypes and local-regional control of breast cancer; Intraoperative margin assessment in breast cancer management; Triple negative breast cancer: who should receive neoadjuvant chemotherapy?; and more!


Changing Paradigms in Breast Cancer Diagnosis and Treatment, an Issue of Surgical Oncology Clinics of North America

Changing Paradigms in Breast Cancer Diagnosis and Treatment, an Issue of Surgical Oncology Clinics of North America
Author: Kelly K. Hunt
Publisher: Elsevier
Total Pages:
Release: 2017-12-05
Genre:
ISBN: 9780323566599

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This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Kelly Hunt, is devoted to Changing Paradigms in Breast Cancer Diagnosis and Treatment. Dr. Hunt has assembled expert authors to review the following topics: Tomosynthesis in breast cancer imaging: how does it fit into preoperative evaluation and surveillance?; Lobular breast cancer: different disease, different algorithms?; Hypofractionated radiation therapy in breast conserving therapy; Oncoplastic breast reconstruction: should all patients be considered?; Neoadjuvant endocrine therapy: who benefits most?; Breast cancer disparities: how can we leverage genomics to improve outcomes?; Anatomy and breast cancer staging: is it still relevant?; When does atypical ductal hyperplasia require surgical intervention?; Surgical intervention for lymphedema; Are there alternative strategies in the local management of DCIS?; Genetic testing and genetic counseling: what is standard of care?; Molecular subtypes and local-regional control of breast cancer; Intraoperative margin assessment in breast cancer management; Triple negative breast cancer: who should receive neoadjuvant chemotherapy?; and more!


Changing Paradigm in Breast Cancer Management

Changing Paradigm in Breast Cancer Management
Author: Mehta Ajay
Publisher: JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
Total Pages: 118
Release: 2011-02-28
Genre:
ISBN: 9350258285

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In this fast pace moving world of change in science and technology, this book describes the changing faces in medical practice in management of breast cancer. 50s was the era of "Clinical Sciences" based on anatomicopathologic data and good clinical medicine. The 60s-70s was the era of "Technological Sciences" based on imaging and instrumentations. The 80s-90s was the era of "Biological Sciences-Molecular Biology, Molecular Genetics, based on laboratory medicine-Beyond Morphology. The text begins with epidemiology and screening of breast cancer, followed by early detection of breast cancer, TN.


Accelerated Partial Breast Irradiation

Accelerated Partial Breast Irradiation
Author: Douglas W. Arthur
Publisher: Springer
Total Pages: 296
Release: 2006-05-23
Genre: Medical
ISBN:

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This text is a concise handbook designed to assist the clinician in the implementation of Accelerated Partial Breast Irradiation (APBI). It includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications. The book encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation.


Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers

Therapeutic Monoclonal Antibodies and Antibody Products, Their Optimization and Drug Design in Cancers
Author: Veysel Kayser
Publisher: Mdpi AG
Total Pages: 298
Release: 2022-01-25
Genre:
ISBN: 9783036526874

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The book broadly deals with therapeutic monoclonal antibodies (mAbs) and various relevant topics, including different antibody formats such as Antibody-Drug Conjugates (ADC), bispecifics, nanoparticle-based mAbs and HER2+ cancers, immune checkpoint inhibitors and other closely related topics. Each paper was written by leading active research groups in their fields both from academia and industry. The book should be of interest to those scientists and researchers who develop or use biologics, biotherapeutics, biosimilars and biobetters in cancer treatment.


Constitutional Oncogenetics

Constitutional Oncogenetics
Author: Noureddine Boukhatem
Publisher: John Wiley & Sons
Total Pages: 288
Release: 2021-03-05
Genre: Medical
ISBN: 1119818109

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In the age of genomics, oncogenetics is a growing discipline. It is defined as the identification and management of families where there is a suspected hereditary risk of cancer. This relatively new discipline is part of a modern medicine that aims to be both preventive and predictive. Constitutional Oncogenetics gives precise descriptions of the main syndromes that cause a predisposition for cancer. The first part examines the most common syndromes in the majority of the world, including the heightened hereditary risk of breast and ovarian cancer and Lynch syndrome. The second part introduces less common infracentesimal syndromes, such as Bloom syndrome and Fanconi syndrome. This book is intended for oncogenetic practitioners and other specialists, as well as medical students.


HER2-Positive Breast Cancer

HER2-Positive Breast Cancer
Author: Sara Hurvitz
Publisher: Elsevier Health Sciences
Total Pages: 264
Release: 2018-07-26
Genre: Medical
ISBN: 0323581234

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Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.


The Drug Development Paradigm in Oncology

The Drug Development Paradigm in Oncology
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 145
Release: 2018-02-12
Genre: Medical
ISBN: 0309457971

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Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.