Cerebral Blood Flow And Metabolism PDF Download
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| Author | : Marilyn J. Cipolla |
| Publisher | : Biota Publishing |
| Total Pages | : 82 |
| Release | : 2016-07-28 |
| Genre | : Medical |
| ISBN | : 1615047239 |
Download The Cerebral Circulation Book in PDF, ePub and Kindle
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
| Author | : Lars Edvinsson |
| Publisher | : |
| Total Pages | : 521 |
| Release | : 2002 |
| Genre | : Science |
| ISBN | : 9780781722599 |
Download Cerebral Blood Flow and Metabolism Book in PDF, ePub and Kindle
Written and edited by the world's foremost authorities, the Second Edition of this landmark work is a current, comprehensive reference on cerebral blood flow and metabolism. The book covers the entire field in a systematic and coherent way and synthesizes the diverse body of basic science and clinical literature. The reader will gain a complete understanding of the anatomical, physiological, and pharmacological bases of the cerebral circulation, its regulation in health and disease, and the pathophysiological disturbances occurring in cerebrovascular disorders. Coverage includes stimulating discussions of future directions for research and therapeutic intervention.
| Author | : Alexander Murray Harper |
| Publisher | : Manchester University Press |
| Total Pages | : 132 |
| Release | : 1990 |
| Genre | : Brain |
| ISBN | : 9780719028939 |
Download Cerebral Blood Flow and Metabolism Book in PDF, ePub and Kindle
An outgrowth of a 1987 teaching seminar at the U. of Glasgow, designed to update physiologists--particularly those in teaching positions--on the recent developments in the relation of cerebral blood flow to metabolism. The five papers might also be useful directly to graduate medical students. Distributed in the US by St. Martin's Press. Annotation copyrighted by Book News, Inc., Portland, OR
| Author | : Lars Edvinsson |
| Publisher | : Raven Press (ID) |
| Total Pages | : 710 |
| Release | : 1993 |
| Genre | : Medical |
| ISBN | : |
Download Cerebral Blood Flow and Metabolism Book in PDF, ePub and Kindle
This text aims to provide the reader with a complete understanding of the anatomical, physiological and pharmacological bases of the cerebral circulation, its regulation in health and disease and the pathophysiological disturbances occurring in cerebrovascular disorders.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 436 |
| Release | : 1972-01-01 |
| Genre | : Medical |
| ISBN | : 9780080861609 |
Download Cerebral Blood Flow Book in PDF, ePub and Kindle
Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
| Author | : Payne Stephen John |
| Publisher | : World Scientific |
| Total Pages | : 468 |
| Release | : 2017-10-06 |
| Genre | : Medical |
| ISBN | : 9813220589 |
Download Cerebral Blood Flow And Metabolism: A Quantitative Approach Book in PDF, ePub and Kindle
This book describes the way in which the human brain is supplied with blood and how the brain uses this to provide nutrients, primarily oxygen and glucose, to brain cells in order to maintain healthy brain function. In particular, it focuses on the quantitative nature of blood flow and metabolism. The book covers models of blood flow and metabolism and how these can be measured using a variety of imaging and non-imaging techniques. It also examines how cerebral blood flow is controlled in response to a wide variety of challenges and how it changes with normal physiological variation and in response to a large number of pathological conditions, including stroke and dementia. As the first substantial book for over ten years in a fast-changing field, it highlights how the subject has progressed in the last couple of decades. It tackles the subject in a quantitative way, underlining its importance in both technical and clinical fields. Audiences with a technical or clinical background, especially researchers and postgraduate students in biomedical engineering or medicine, will find this a valuable read. Contents: Physiology of Blood Flow and MetabolismModels of Blood Flow and MetabolismGlobal Control of Blood FlowLocal Control of PerfusionExternally-based MeasurementsInternally-based MeasurementsGlobal Changes in Cerebral Blood Flow and MetabolismLocal Changes in Cerebral Blood Flow and MetabolismConclusions Readership: Researchers and postgraduate students in biomedical engineering and medicine. Keywords: Brain;Haemodynamics;Vascular;Neurovascular;Autoregulation;Brain imagingReview: Key Features: Focus on quantitative measurements and models, and their application in clinical practiceCoverage aimed at both technical and clinical audienceUp-to-date coverage of a very broad field, with no recent equivalent text
| Author | : Anish Bhardwaj |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 337 |
| Release | : 2004-05-25 |
| Genre | : Medical |
| ISBN | : 1592597726 |
Download Handbook of Neurocritical Care Book in PDF, ePub and Kindle
Neurocritical care as a subspecialty has grown rapidly over the last 20 years with the advent of newer monitoring and diagnostic techniques and therapeutic modalities in a variety of brain and spinal cord injury paradigms. This handbook will serve as a quick reference guide to all health care providers in a neurocritical care setting. Since time is of the essence in the rapid diagnosis and timely therapeutic interventions for these patients, this book provides an algorithmic approach to making a clinical diagnosis using ancillary investigations to confirm the diagnosis and provide appropriate management of acute neurologic diseases. Tables and illustrations help provide a quick and easy bedside reference and give a practical approach to the management of these patients.
| Author | : Pan-Dong Ryu |
| Publisher | : Springer Nature |
| Total Pages | : 431 |
| Release | : 2019-12-31 |
| Genre | : Medical |
| ISBN | : 3030344614 |
Download Oxygen Transport to Tissue XLI Book in PDF, ePub and Kindle
This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 46th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2018) held in Seoul, Republic of Korea, from July 1 to July 5, 2018. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.
| Author | : Matthew E. Cross |
| Publisher | : Cambridge University Press |
| Total Pages | : 439 |
| Release | : 2014-03-06 |
| Genre | : Medical |
| ISBN | : 1107615887 |
Download Physics, Pharmacology and Physiology for Anaesthetists Book in PDF, ePub and Kindle
A quick reference to basic science for anaesthetists, containing all the key information needed for FRCA exams.
| Author | : A. Hartmann |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 631 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642700543 |
Download Cerebral Blood Flow and Metabolism Measurement Book in PDF, ePub and Kindle
At the present time several techniques are available for studying quantitatively global and regional blood flow and metabolism of the human brain. How ever, many scientists working in the clinical and research field who would like to use these tools for their investigations may be less familiar with the indi cations and limitations of the individual methods. The rapid development of both modern imaging techniques and new tracers may have led to some con fusion in answering the question as to which method is appropriate to solve the diagnostic problem of an individuum with brain disease. Scepticism and ignorance as to the methods to be used as tools in differential diagnosis of brain disorders may have prevented their widespread introduction into clinical practice. Thus, the significance of circulatory and metabolic parameters involved in the majority of diseases of the central nervous system may have been overlooked. The contributions compiled in this book describe in detail the individual techniques, outline their indications and limitations and deal in particular with newer methods such as the atraumatic 133Xe technique, stable xenon tomogra phy, three-dimensional techniques such as 133Xe single photon emission tomog raphy and N-isopropyl-P23-iodoamphetamine. Positron emission tomography studies provide information on function and metabolism, particularly that of oxygen and glucose, in regional brain areas of interest. Nuclear magnetic reso nance may be a promising method for studying metabolic parameters; however, accurate circulation measurements can not be performed at present.
